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US5656591A Expired / Lapsed US ⏱️ 0.0 years remaining

Antimicrobial agents and method for treating products therewith

Assignee: Morinaga Milk Industry Co Ltd
•
Filing: 1992-11-30
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Granted: 1997-08-12
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Expires: 2012-11-30
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Abstract

Abstract There is disclosed an antimicrobial agent comprising one or more of antimicrobial peptides derived from lactoferrins, and one or more of specific compounds and/or at least an antibiotic, and a method for treating matters with said antimicrobial agent. The antimicrobial agent has a potent antimicrobial activity against wide variety of microorganisms, thus it is useful not only as a medication, but also useful for making antimicrobial treatment of matters such as foods, non-medical products, and the like with safety and great efficiency.

Inventors

  • 👤 Mamoru Tomita
  • 👤 Seiichi Shimamura
  • 👤 Kozo Kawase
  • 👤 Yasuo Fukuwatari
  • 👤 Mitsunori Takase
  • 👤 Wayne Robert Bellamy
  • 👤 Koji Yamauchi
  • 👤 Hiroyuki Wakabayashi
  • 👤 Yukiko Tokita

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 13:20
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/79; A; A01; A01N; A01N63/00; A01N63/50; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/425; A61K31/429; A61K31/43; A61K38/00; A61K38/04; A61K38/12; A61K45/00; A61K45/06; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/833

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 76 words
An antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodextrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid, wherein component (B) is present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 2
Dependent Claim 76 words
An antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodextrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid, wherein component (B) is present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 3
Dependent Claim 69 words
An antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 1-32 and (C) at least an antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs, wherein component (C) is present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 4
Dependent Claim 69 words
An antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 1-32 and (C) at least an antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs, wherein component (C) is present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 5
Dependent Claim 96 words
An antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodexrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid and (C) at least an antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs, wherein components (B) and (C) are present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 6
Dependent Claim 96 words
An antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodexrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid and (C) at least an antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs, wherein components (B) and (C) are present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 7
Independent Claim 84 words
A method for treatment of a matter with at antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodextrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid, wherein component (B) is present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 8
Independent Claim 84 words
A method for treatment of a matter with at antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodextrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid, wherein component (B) is present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 9
Independent Claim 61 words
A method for treatment of a matter with an antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (C) at least one antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs.
Claim 10
Independent Claim 61 words
A method for treatment of a matter with an antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (C) at least one antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs.
Claim 11
Independent Claim 104 words
A method of treatment of a matter with an antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodextrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid, and (C) at least one antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs wherein components (B) and (C) are present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).
Claim 12
Independent Claim 104 words
A method of treatment of a matter with an antimicrobial agent consisting essentially of (A) one or more of substantially purified and isolated antimicrobial peptides consisting of an amino acid sequence selected from the group consisting of SEQ ID Nos. 10-30 and 32 and (B) one or more compounds selected from the group consisting of tocopherol, cyclodextrin, glycerin-fatty acid ester, alcohol, chitosan, cysteine, and cholic acid, and (C) at least one antibiotic selected from the group consisting of tetracycline antibiotics, penicillin, and antituberculosis drugs wherein components (B) and (C) are present in amounts sufficient to increase the antimicrobial effects of the antimicrobial peptide (A).

References Cited (Backward Citations)

JPS59141507A Cited
JPS62129202A Cited
JPH02191205A Cited
US4980163A Cited
JPH03504864A Cited
JPH03193708A Cited
US5198419A Cited
US5214028A Cited
US5389611A Cited
JPH03220130A Cited
US5317084A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2000-08-11 2001-02-10 2001-08-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2004-08-11 2005-02-10 2005-08-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2008-08-11 2009-02-10 2009-08-12 $7700.00 Window Closed / Lapsed

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