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US5606019A Expired / Lapsed US ⏱️ 0.0 years remaining

Synthetic protein as implantables

Assignee: Protein Polymer Technologies Inc
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Filing: 1994-03-11
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Granted: 1997-02-25
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Expires: 2014-03-11
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Abstract

Abstract Copolymers are provided having varying ratios of elastin and fibroin repeating units. By varying the length of segments of the elastin and fibroin repeating units, the absorption can be greatly varied. Tensile strengths remain relatively constant regardless of the composition within the prescribed ranges. The copolymer compositions and recombinant fibroin can be used for the production of a wide variety of formed objects and amorphous masses for use as implants.

Inventors

  • 👤 Joseph Cappello

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 08:46
CPC Classifications
D; D01; D01F; D01F4/00; A; A61; A61L; A61L17/00; A61L17/06; A61L17/10; A61L27/00; A61L27/14; A61L27/22; A61L27/227; A61L31/00; A61L31/04; A61L31/043; A61L31/047; C; C07; C07K; C07K14/00; C07K14/435; C07K14/78; C08; C08J; C08J5/00; C08J5/18; C12; C12N; C12N15/00; C12N15/09; C12N15/11; A61K; A61K38/00; C07K2319/00; C07K2319/01; C07K2319/02; C07K2319/61; C08J2389/00

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 50 words
A protein polymer of at least 15 kD and comprising alternating blocks of two units each of VPGVG (SEQ ID NO: 02) and GAGAGS (SEG ID NO: 01), wherein at least 15 to 80% of amino acids of said alternating blocks of said protein polymer are present as GAGAGS units.
Claim 2
Dependent Claim 50 words
A protein polymer of at least 15 kD and comprising alternating blocks of two units each of VPGVG (SEQ ID NO: 02) and GAGAGS (SEG ID NO: 01), wherein at least 15 to 80% of amino acids of said alternating blocks of said protein polymer are present as GAGAGS units.
Claim 3
Dependent Claim 33 words
A protein polymer according to claim 1, wherein blocks of VPGVG (SEQ ID NO:02) have from two to thirty-two units and blocks of GAGAGS (SEQ ID NO:02) have from two to twelve units.
Claim 4
Dependent Claim 21 words
A protein polymer according to claim 2, wherein said blocks of VPGVG (SEQ ID NO:02) have from eight to twenty units.
Claim 5
Dependent Claim 34 words
A protein polymer according to claim 1, wherein said protein polymer has blocks of VPGVG (SEQ ID NO:02) and GAGAGS (SEQ ID NO:01) with unit ratios of: 8:2; 8:4; 8:6; 12:8; 16:8; and 32:8.

References Cited (Backward Citations)

US4215200A Cited
US4589882A Cited
US5243038A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2000-02-25 2000-08-26 2001-02-25 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2004-02-25 2004-08-26 2005-02-25 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2008-02-25 2008-08-26 2009-02-25 $7700.00 Window Closed / Lapsed

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