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US5571784A Expired / Lapsed US ⏱️ 0.0 years remaining

Use of VWF-containing concentrates as a therapy which is employed in combination with antithrombotic and fibrinolytic therapy

Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1995-10-18
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Granted: 1996-11-05
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Expires: 2015-10-18
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Abstract

Abstract The invention relates to the administration of von Willebrand factor (vWF)-containing drugs in association with the therapeutic use of blood anticoagulants, either on their own or together with fibrinolytics. The administration, which is for the purpose of reducing the risk of hemorrhages in patients, can take place either at the same time or following the anticoagulant and lytic treatment. A therapy principle is described which separates, during therapy, the desirable effect of anticoagulation and/or fibrinolysis from the undesirable side effect of hemorrhagic tendency.

Inventors

  • 👤 Martin Reers
  • 👤 Gerhard Dickneite

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 23:25
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/36; A61K38/37; A61P; A61P7/00; A61P7/02; A61P7/04

Claims Analysis

Total Claims: 3
Claim 1
Independent Claim 39 words
A method for decreasing the bleeding side effect in a patient caused by administering anticoagulant and/or fibrinolytic agents comprising administering to said patient a therapeutically active amount of von Willibrand Factor, or a fragment having von Willibrand Factor activity.
Claim 2
Independent Claim 39 words
A method for decreasing the bleeding side effect in a patient caused by administering anticoagulant and/or fibrinolytic agents comprising administering to said patient a therapeutically active amount of von Willibrand Factor, or a fragment having von Willibrand Factor activity.
Claim 3
Dependent Claim 30 words
The method according to claim 1, wherein in addition to said von Willibrand Factor, or a fragment having von Willibrand Factor activity, an antithrombotic agent and/or fibrinolytic agent is administered.

References Cited (Backward Citations)

US5198349A Cited
US5200510A Cited
US4774323A Cited
US5112950A Cited
EP0367713B1 Cited
US5204323A Cited
US5204323B1 Cited
US5408039A Cited
WO1992020361A1 Cited
US5366869A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-11-05 2000-05-06 2000-11-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-11-05 2004-05-06 2004-11-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-11-05 2008-05-06 2008-11-05 $7700.00 Window Closed / Lapsed

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