← Back to Patent Explorer
US5542410A Expired / Lapsed US ⏱️ 0.0 years remaining

Delivery of aeerosol medications for inspiration

Assignee: Aradigm Corp
•
Filing: 1994-12-09
•
Granted: 1996-08-06
•
Expires: 2014-12-09
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract Apparatus and methods for delivering an amount of aerosolized medicine for inspiration by a patient in response to the occurrence of appropriate delivery point or points in the patient's detected breath flow. The aerosol medication may be administered as one or more pulses having a pulse width, shape, and frequency that will maximize the respirable fraction of the aerosolized compound being administered. The delivery point or points may be predetermined or determined from a prior inspiratory flow for depositing the selected medication at one or more desired locations in the patient's airway. Determined delivery points are recursively lowered for each inspiratory flow that does not satisfy one of the predetermined and previously lowered threshold. Changes in the patient's breath flow patterns during the course of an aerosolized medication inspiration therapy program may be detected and used to adjust the controlled amount of medication to be delivered in a given administration and/or to inform the patient of the patient's condition or change in condition. The device also may contain a library of administration protocols or operating parameters for different medications and a means for identifying from the canister the medicinal contents of the canister for customizing operation of the apparatus.

Inventors

  • 👤 David E. Goodman
  • 👤 Reid M. Rubsamen

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 22:49
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0091; A61M15/0001; A61M15/0021; A61M15/0065; A61M15/0066; A61M15/0068; A61M15/008; A61M16/00; A61M16/20; A61M16/201; A61M16/202; B; B01; B01F; B01F23/00; B01F23/20; B01F23/21; B01F23/213; B01F23/2132; B01F35/00; B01F35/71; B01F35/711; B01F35/717; B01F35/7179; F; F16; F16H; F16H35/00; G; G01; G01F; G01F1/00; G01F1/05; G01F1/34; G01F1/36; G01F1/363; G01F1/40; G01F1/44; G01F1/50; G01F13/00; G01F13/006; G01F15/00; G01F15/001; G01F15/002; G01F25/00; G01F25/10; G01F7/00; G01F7/005; A61J; A61J7/00; A61J7/04; A61J7/0409; A61J7/0418; A61M11/00; A61M11/001; A61M11/002; A61M15/009; A61M16/08; A61M16/0816; A61M16/0841; A61M16/0858; A61M16/0003; A61M2016/0015; A61M2016/0018; A61M2016/0021; A61M2016/003; A61M2016/0033; A61M2016/0036; A61M2016/0039; A61M2205/00; A61M2205/50; A61M2205/60; A61M2205/6018; A61M2205/6027; A61M2205/6036; A61M2205/6045; A61M2205/82; A61M2205/8206; A61M2205/8212

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 148 words
A battery powered, portable, hand-held device for delivering an aerosolized medication to a patient for inspiration, comprising: a tube forming a flow path from an open end to a mouth end; a reservoir of a selected medication having an identification code thereon; a means for determining the medication in the reservoir based on the identification code; a nozzle for releasing and aerosolizing medication from the reservoir to the open end of the tube; a flow transducer for measuring the patient's breath flow through the tube; a microprocessor for calculating a medication delivery point based on information from the flow transducer; an actuating mechanism which initiates release of medication through the nozzle and into the tube upon receipt of a signal sent after the microprocessor has determined that the patient's breath flow is at the delivery point; and a motion detector for determining when the reservoir has been agitated.
Claim 2
Dependent Claim 148 words
A battery powered, portable, hand-held device for delivering an aerosolized medication to a patient for inspiration, comprising: a tube forming a flow path from an open end to a mouth end; a reservoir of a selected medication having an identification code thereon; a means for determining the medication in the reservoir based on the identification code; a nozzle for releasing and aerosolizing medication from the reservoir to the open end of the tube; a flow transducer for measuring the patient's breath flow through the tube; a microprocessor for calculating a medication delivery point based on information from the flow transducer; an actuating mechanism which initiates release of medication through the nozzle and into the tube upon receipt of a signal sent after the microprocessor has determined that the patient's breath flow is at the delivery point; and a motion detector for determining when the reservoir has been agitated.
Claim 3
Dependent Claim 18 words
The device off claim 1 wherein the delivery point is calculated to maximize the efficacy of the medication.
Claim 4
Dependent Claim 22 words
The device of claim 2, further comprising: a means for detecting breath parameters of the patient including inspiratory flow and expiratory flow.
Claim 5
Dependent Claim 18 words
The device of claim 3, further comprising: a visual indicator providing a visual display of detected breath parameters.
Claim 6
Dependent Claim 17 words
The device of claim 1 wherein the microprocessor includes a library of administration protocols for different medications.

References Cited (Backward Citations)

US29117A Cited
US3157179A Cited
US3187748A Cited
US3356088A Cited
US3211346A Cited
US3394851A Cited
GB1201918A Cited
US3456646A Cited
US3456644A Cited
US3456645A Cited
US3464596A Cited
US3658059A Cited
US3565070A Cited
GB1270272A Cited
US3636949A Cited
DE2039862A1 Cited
US3789843A Cited
US3826413A Cited
FR2147177A1 Cited
US3814297A Cited
GB1426583A Cited
US3830404A Cited
GB1484010A Cited
US3878973A Cited
US3940023A Cited
US3974941A Cited
US3952916A Cited
US3991304A Cited
US3968905A Cited
US4124149A Cited
US4117958A Cited
US4106503A Cited
DE2809255A1 Cited
GB2004526A Cited
US4361401A Cited
FR2437248A1 Cited
US4291688A Cited
US4256017A Cited
US4446862A Cited
US4558710A Cited
EP0045419A1 Cited
US4386553A Cited
US4366743A Cited
US4860740A Cited
US4427137A Cited
US4413755A Cited
US4524769A Cited
US4484577A Cited
GB2104393A Cited
US4469255A Cited
US4462398A Cited
EP0136383A1 Cited
US4576157A Cited
US4664107A Cited
US4702400A Cited
US4534343A Cited
US4662537A Cited
US4679555A Cited
US4624251A Cited
US4677975A Cited
US4648393A Cited
US4592348A Cited
US4942544A Cited
US4682713A Cited
SU1377106A1 Cited
US4803978A Cited
US5133343A Cited
GB2186949A Cited
EP0232235A2 Cited
US4934358A Cited
WO1987005813A1 Cited
US4932402A Cited
DE3617400A1 Cited
US4790305A Cited
US4926852A Cited
US4926852B1 Cited
US4745925A Cited
US4819629A Cited
US4832012A Cited
US4805609A Cited
EP0302958A1 Cited
US4896832A Cited
US4852582A Cited
US5293865A Cited
US4933873A Cited
US4922901A Cited
US4984158A Cited
DE3901963C1 Cited
US5069204A Cited
WO1992007599A1 Cited
US5404871A Cited
US5363842A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-08-06 2000-02-05 2000-08-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-08-06 2004-02-05 2004-08-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-08-06 2008-02-05 2008-08-06 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag