Patent US5540680A successfully refreshed from Google Patents.
US5540680A
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Endovascular electrolytically detachable wire and tip for the formation of thrombus in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas
Assignee: University of California, San Diego
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Filing: 1994-09-23
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Granted: 1996-07-30
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Expires: 2014-09-23
Abstract
Abstract An artery, vein, aneurysm, vascular malformation or arterial fistula is occluded through endovascular occlusion by the endovascular insertion of a platinum wire and/or tip into the vascular cavity. The vascular cavity is packed with the tip to obstruct blood flow or access of blood in the cavity such that the blood clots in the cavity and an occlusion if formed. The tip may be elongate and flexible so that it packs the cavity by being folded upon itself a multiple number of times, or may pack the cavity by virtue of a filamentary or fuzzy structure of the tip. The tip is then separated from the wire mechanically or by electrolytic separation of the tip from the wire. The wire and the microcatheter are thereafter removed leaving the tip embedded in the thrombus formed within the vascular cavity. Movement of wire in the microcatheter is more easily tracked by providing a radioopaque proximal marker on the microcatheter and a corresponding indicator marker on the wire. Electrothrombosis is facilitate by placing the ground electrode on the distal end of the microcatheter and flowing current between the microcatheter electrode and the tip.
Inventors
- 👤 Guido Guglielmi
- 👤 Ivan Sepetka
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 01:06
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/09; A61B; A61B17/00; A61B17/12; A61B17/12022; A61B17/12099; A61B17/12109; A61B17/12113; A61B17/12131; A61B17/1214; A61B17/12145; A61B17/1215; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B17/00234; A61B2017/00292; A61B2017/1205; A61B2017/12054; A61B2017/12063; A61B2017/12095; A61B17/22; A61B2017/22038; A61B2018/00636; A61B2018/00666; A61B2018/00678; A61B2018/00696; A61B2018/00761; A61B2018/00773; A61B2018/00875; A61B2018/00886; A61B18/1206; A61B2018/1226; A61B2018/1246; A61B2018/1253; A61B2018/126; A61B2018/1266; A61B2018/1405; A61B2018/1435; A61B2018/1495; A61B90/00; A61B90/39; A61B2090/3966; A61M2025/09175
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
94 words
A method for forming an occlusion within a vascular cavity having blood disposed therein comprising the steps of: endovascularly disposing a guidewire near an endovascular opening into said vascular cavity; disposing a distal tip of said guidewire into said vascular cavity to pack said cavity to mechanically form said occlusion within said vascular cavity about said distal tip, and detaching said distal tip from said guidewire to leave said distal tip within said vascular cavity, whereby said vascular cavity is occluded by said distal tip, and any thrombus formed by use of said tip.
Claim 2
Independent Claim
94 words
A method for forming an occlusion within a vascular cavity having blood disposed therein comprising the steps of: endovascularly disposing a guidewire near an endovascular opening into said vascular cavity; disposing a distal tip of said guidewire into said vascular cavity to pack said cavity to mechanically form said occlusion within said vascular cavity about said distal tip, and detaching said distal tip from said guidewire to leave said distal tip within said vascular cavity, whereby said vascular cavity is occluded by said distal tip, and any thrombus formed by use of said tip.
Claim 3
Dependent Claim
28 words
The method of claim 1 wherein said step of detaching said distal tip from said wire comprises the step of mechanically detaching said distal tip from said wire.
Claim 4
Dependent Claim
83 words
The method of claim 1 where said wire and tip are used within a microcatheter and where in said step of detaching said distal tip from said wire, said wire and tip are longitudinally displaced within said microcatheter, said microcatheter having a radio-opaque proximal marker, said wire and tip having collectively a single radio-opaque marker, said displacement of said wire and tip moving said single radio-opaque marker to the proximity of said proximal marker on said microcatheter when said tip is fully deployed.
Claim 5
Dependent Claim
41 words
The method of claim 1 wherein said step of disposing said tip into said vascular cavity to pack said cavity comprises the step of disposing a long flexible tip folded upon itself a multiple number of times to pack said cavity.
Claim 6
Independent Claim
127 words
A method for forming an occlusion within a vascular cavity having blood disposed therein comprising the steps of: endovascularly disposing a wire near an endovascular opening into said vascular cavity; disposing a distal tip of said wire into said vascular cavity to pack said cavity to mechanically form said occlusion within said vascular cavity about said distal tip: and detaching said distal tip from said wire to leave said distal tip within said vascular cavity, wherein said step of disposing said tip into said vascular cavity to pack said cavity comprises the step of disposing a tip having a plurality of filaments extending therefrom to pack said cavity, whereby said vascular cavity is occluded by said distal tip, and any thrombus formed by use of said tip.
Claim 7
Independent Claim
127 words
A method for forming an occlusion within a vascular cavity having blood disposed therein comprising the steps of: endovascularly disposing a wire near an endovascular opening into said vascular cavity; disposing a distal tip of said wire into said vascular cavity to pack said cavity to mechanically form said occlusion within said vascular cavity about said distal tip: and detaching said distal tip from said wire to leave said distal tip within said vascular cavity, wherein said step of disposing said tip into said vascular cavity to pack said cavity comprises the step of disposing a tip having a plurality of filaments extending therefrom to pack said cavity, whereby said vascular cavity is occluded by said distal tip, and any thrombus formed by use of said tip.
Claim 8
Dependent Claim
84 words
A wire for use in formation of an occlusion within a vascular cavity used in combination with a microcatheter comprising: a core wire having a distal end; and a detachable elongate tip portion extending said core wire for a predetermined lineal extent adapted to being packed into said vascular cavity to form said occlusion in said vascular cavity, said detachable elongate tip portion being temporarily coupled to said distal end of said core wire, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 9
Dependent Claim
84 words
A wire for use in formation of an occlusion within a vascular cavity used in combination with a microcatheter comprising: a core wire having a distal end; and a detachable elongate tip portion extending said core wire for a predetermined lineal extent adapted to being packed into said vascular cavity to form said occlusion in said vascular cavity, said detachable elongate tip portion being temporarily coupled to said distal end of said core wire, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 10
Dependent Claim
30 words
The wire of claim 6 wherein said elongate tip portion is a long and substantially pliable segment adapted to be multiply folded upon itself to substantially pack said vascular cavity.
Claim 11
Dependent Claim
67 words
The wire of claim 6 wherein said microcatheter has a pair of radioopaque markers disposed thereon and wherein said core wire has a radioopaque marker disposed thereon, said marker on said core wire being positioned in the proximity of one of said pair of markers on said microcatheter when said core wire is deployed, said other marker on said microcatheter indicating the distal end of said microcatheter.
Claim 12
Dependent Claim
15 words
The wire of claim 6 where said core wire and tip are coupled by polyester.
Claim 13
Dependent Claim
117 words
A wire for use in formation of an occlusion within a vascular cavity used in combination with a microcatheter comprising: a core wire having a distal end; and a detachable elongate tip portion extending said core wire for a predetermined lineal extent adapted to being packed into said vascular cavity to form said occlusion in said vascular cavity, said detachable elongate tip portion being temporarily coupled to said distal end of said core wire, wherein said elongate tip portion is a segment adapted to be disposed in said vascular cavity and having a plurality of filaments extending therefrom to substantially pack said vascular cavity when disposed therein, whereby endovascular occlusion of said vascular cavity can be performed.
Claim 14
Dependent Claim
117 words
A wire for use in formation of an occlusion within a vascular cavity used in combination with a microcatheter comprising: a core wire having a distal end; and a detachable elongate tip portion extending said core wire for a predetermined lineal extent adapted to being packed into said vascular cavity to form said occlusion in said vascular cavity, said detachable elongate tip portion being temporarily coupled to said distal end of said core wire, wherein said elongate tip portion is a segment adapted to be disposed in said vascular cavity and having a plurality of filaments extending therefrom to substantially pack said vascular cavity when disposed therein, whereby endovascular occlusion of said vascular cavity can be performed.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-07-30 | 2000-01-29 | 2000-07-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-07-30 | 2004-01-29 | 2004-07-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-07-30 | 2008-01-29 | 2008-07-30 | $7700.00 | Window Closed / Lapsed |