US5503869A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for forming medicament carrier for dry powder inhalator
Assignee: SmithKline Beecham Corp
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Filing: 1994-10-21
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Granted: 1996-04-02
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Expires: 2014-10-21
Abstract
Abstract A process for forming a medicament carrier for use in a dry powder inhalator device wherein the medicament carrier has at least one carrier screen portion. The carrier screen portion defines a plurality of interstices therein and carries a powdered medicament, applied in a suspension and the suspending agent then evaporated off, which is substantially loaded onto the screen portion surface such that the interstices of the carrier screen portion are at least partially open and free of the dry powdered medicament.
Inventors
- 👤 Michiel M. Van Oort
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 08:02
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0028; A61M15/0045; A61M15/0046; A61M15/0048; A61M15/005; A61M15/0051; A61M2202/00; A61M2202/06; A61M2202/064
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
106 words
A process for forming a medicament carrier to use in a dry powder inhalator device comprising the steps of: (a) providing a carrier having a plurality of carrier surfaces defining a plurality of interstices therebetween; (b) applying a suspension comprising a suspending agent and at least one dose of a powdered medicament to the carrier surfaces of the carrier so that the interstices are at least partially open and free of the suspension; and (c) evaporating off the suspending agent from the carrier surfaces so as to leave the powdered medicament deposited primarily upon the carrier surfaces of the carrier and not within the interstices thereof.
Claim 2
Dependent Claim
106 words
A process for forming a medicament carrier to use in a dry powder inhalator device comprising the steps of: (a) providing a carrier having a plurality of carrier surfaces defining a plurality of interstices therebetween; (b) applying a suspension comprising a suspending agent and at least one dose of a powdered medicament to the carrier surfaces of the carrier so that the interstices are at least partially open and free of the suspension; and (c) evaporating off the suspending agent from the carrier surfaces so as to leave the powdered medicament deposited primarily upon the carrier surfaces of the carrier and not within the interstices thereof.
Claim 3
Dependent Claim
15 words
The process according to claim 1 wherein said carrier surfaces comprise a carrier screen portion.
Claim 4
Dependent Claim
17 words
The process according to claim 1 wherein said carrier surfaces comprise a plurality of spherical substrate elements.
Claim 5
Dependent Claim
30 words
The process according to claim 1 wherein said medicament is selected from the group consisting of albuterol, terbutaline, isoproterenol, metaprotaranol, pirbuterol, salmeterol hydroxynapthoate, fluticasone propionate, budesonide, beclomethasone dipropionate, and triacetonide.
Claim 6
Dependent Claim
23 words
The process according to claim 1 wherein the suspending agent is selected from the group consisting of fluorinated hydrocarbons, hydrocarbons, and mixtures thereof.
Claim 7
Dependent Claim
24 words
The process according to claim 5 wherein the fluorinated hydrocarbon suspending agent is selected from the group consisting of perfluoropentane, perfluorohexane, perfluoromethylcyclohexane, and perfluorocyclohexane.
Claim 8
Dependent Claim
114 words
A process for forming a medicament carrier to use in a dry powder inhalator device comprising the steps of: (a) providing a carrier having at least one carrier screen portion including a plurality of carrier surfaces defining a plurality of interstices therebetween; (b) applying a suspension comprising a suspending agent and at least one dose of a powdered medicament to the surfaces of the carrier screen portion so that the interstices are at least partially open and free of the suspension; and (c) evaporating off the suspending agent from the carrier screen portion so as to leave the powdered medicament deposited primarily upon the surfaces of the carrier and not within the interstices thereof.
Claim 9
Dependent Claim
114 words
A process for forming a medicament carrier to use in a dry powder inhalator device comprising the steps of: (a) providing a carrier having at least one carrier screen portion including a plurality of carrier surfaces defining a plurality of interstices therebetween; (b) applying a suspension comprising a suspending agent and at least one dose of a powdered medicament to the surfaces of the carrier screen portion so that the interstices are at least partially open and free of the suspension; and (c) evaporating off the suspending agent from the carrier screen portion so as to leave the powdered medicament deposited primarily upon the surfaces of the carrier and not within the interstices thereof.
Claim 10
Dependent Claim
30 words
The process according to claim 7 wherein said medicament is selected from the group consisting of albuterol, terbutaline, isoproterenol, metaprotaranol, pirbuterol, salmeterol hydroxynapthoate, fluticasone propionate, budesonide, beclomethasone dipropionate, and triacetonide.
Claim 11
Dependent Claim
23 words
The process according to claim 7 wherein the suspending agent is selected from the group consisting of fluorinated hydrocarbons, hydrocarbons, and mixtures thereof.
Claim 12
Dependent Claim
24 words
The process according to claim 9 wherein the fluorinated hydrocarbon suspending agent is selected from the group consisting of perfluoropentane, perfluorohexane, perfluoromethylcyclohexane, and perfluorocyclohexane.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-04-02 | 1999-10-02 | 2000-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-04-02 | 2003-10-02 | 2004-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-04-02 | 2007-10-02 | 2008-04-02 | $7700.00 | Window Closed / Lapsed |