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US4601897A Expired / Lapsed US ⏱️ 0.0 years remaining

Prazosin-pirbuterol combination for bronchodilation

Assignee: Pfizer Inc
•
Filing: 1985-11-06
•
Granted: 1986-07-22
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Expires: 2005-11-06
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Abstract

Abstract A method for relaxing bronchial tissue in mammals, including humans, by use of a combination of prazosin and pirbuterol or their pharmaceutically acceptable acid addition salts.

Inventors

  • 👤 Craig A. P. D. Saxton

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 21:55
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/495; A61K31/505; A61P; A61P11/00; A61P11/08

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 59 words
A method for relaxing bronchial tissue in a mammalian subject which comprises contacting said tissue with a bronchodilating effective amount of a mixture of from 10 to 90 parts by weight of prazosin or a pharmaceutically acceptable acid addition salt thereof and from 90 to 10 parts by weight of pirbuterol or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Independent Claim 59 words
A method for relaxing bronchial tissue in a mammalian subject which comprises contacting said tissue with a bronchodilating effective amount of a mixture of from 10 to 90 parts by weight of prazosin or a pharmaceutically acceptable acid addition salt thereof and from 90 to 10 parts by weight of pirbuterol or a pharmaceutically acceptable acid addition salt thereof.
Claim 3
Dependent Claim 29 words
A method according to claim 1 wherein said mixture contains from 20 to 50 parts by weight of prazosin and from 80 to 50 parts by weight of pirbuterol.
Claim 4
Dependent Claim 14 words
A method according to claim 1 wherein prazosin hydrochloride and pirbuterol dihydrochloride are employed.
Claim 5
Dependent Claim 17 words
A method according to claim 1 wherein said contacting is effected by means of an aerosol syray.
Claim 6
Dependent Claim 56 words
A pharmaceutical composition for aerosol syraying which comprises a pharmaceutically acceptable carrier and a bronchodilating effective amount of a mixture of from 10 to 90 parts by weight of prazosin or a pharmaceutically acceptable acid addition salt thereof and from 90 to 10 parts by weight of pirbuterol or a pharmaceutically acceptable acid addition salt thereof.
Claim 7
Dependent Claim 56 words
A pharmaceutical composition for aerosol syraying which comprises a pharmaceutically acceptable carrier and a bronchodilating effective amount of a mixture of from 10 to 90 parts by weight of prazosin or a pharmaceutically acceptable acid addition salt thereof and from 90 to 10 parts by weight of pirbuterol or a pharmaceutically acceptable acid addition salt thereof.
Claim 8
Dependent Claim 30 words
A pharmaceutical composition according to claim 5 wherein said mixture contains from 20 to 50 parts by weight of prazosin and from 80 to 50 parts by weight of pirbuterol.
Claim 9
Dependent Claim 15 words
A pharmaceutical composition according to claim 6 wherein prazosin hydrochloride and pirbuterol dihydrochloride are employed.

References Cited (Backward Citations)

US3511836A Cited
US3700681A Cited
US3786160A Cited
US4092315A Cited
US4175128A Cited
US4271300A Cited
US4539323A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-07-21 1990-01-20 1990-07-22 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-07-21 1994-01-20 1994-07-22 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-07-21 1998-01-20 1998-07-22 $7700.00 Window Closed / Lapsed

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