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US5496534A
Expired / Lapsed
US
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Squid magnetometry using ferri-and ferromagnetic particles
Assignee: GE Healthcare AS
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Filing: 1992-09-28
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Granted: 1996-03-05
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Expires: 2012-09-28
Abstract
Abstract The invention provides the use of a physiologically tolerable, particulate, free or matrix-borne, ferrimagnetic or ferromagnetic material for the manufacture of a diagnostic agent for administration into the gastrointestinal tract, the reproductive tract, the urinary tract, a closed body cavity (e.g. into the synovial fluid or the vasculature) or the musculature for magnetometric imaging of the human or non-human animal body.
Inventors
- 👤 Jo Klaveness
- 👤 Thorfinn Ege
- 👤 Scott M. Rocklage
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 23:13
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/06; A61K49/18; A61K49/1818; A61K49/1887; A61K49/1821; A61K49/1824; A61K49/1827; A61K49/1851; A61K49/1857; Y; Y10; Y10T; Y10T436/00; Y10T436/24
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
63 words
A method of generating a magnetometric image of the human or non-human animal body which method comprises administering into the gastrointestinal tract, the reproductive tract, the urinary tract, a closed body cavity or the musculature of said body a physiologically tolerable particulate-ferromagnetic or ferrimagnetic material and generating a magnetometric image of at least a part of said body into which said material distributes.
Claim 2
Independent Claim
63 words
A method of generating a magnetometric image of the human or non-human animal body which method comprises administering into the gastrointestinal tract, the reproductive tract, the urinary tract, a closed body cavity or the musculature of said body a physiologically tolerable particulate-ferromagnetic or ferrimagnetic material and generating a magnetometric image of at least a part of said body into which said material distributes.
Claim 3
Dependent Claim
30 words
A method as claimed in claim 1 comprising detecting magnetic field perturbations within said body using a SQUID-based magnetometer and generating a two or three dimensional image of said body.
Claim 4
Dependent Claim
21 words
A method as claimed in claim 1 wherein a magnetic resonance image of said body is generated as a reference image.
Claim 5
Dependent Claim
104 words
A process for detecting variations in magnetic susceptibility within a human or non-human animal body which process comprises administering into the gastrointestinal tract, the reproductive tract, the urinary tract, a closed body cavity or the musculature of said body a physiologically tolerable particulate ferromagnetic or ferrimagnetic material, and with a magnetometer continuously or repeatedly monitoring the magnetic susceptibility of at least a part of said body into which said material distributes whereby to generate magnetometric images of variations or abnormalities in blood flow, or to monitor the location and aggregation of these materials within regions of the body, and generate a magnetometric image thereof.
Claim 6
Dependent Claim
104 words
A process for detecting variations in magnetic susceptibility within a human or non-human animal body which process comprises administering into the gastrointestinal tract, the reproductive tract, the urinary tract, a closed body cavity or the musculature of said body a physiologically tolerable particulate ferromagnetic or ferrimagnetic material, and with a magnetometer continuously or repeatedly monitoring the magnetic susceptibility of at least a part of said body into which said material distributes whereby to generate magnetometric images of variations or abnormalities in blood flow, or to monitor the location and aggregation of these materials within regions of the body, and generate a magnetometric image thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1999-03-05 | 1999-09-04 | 2000-03-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2003-03-05 | 2003-09-04 | 2004-03-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2007-03-05 | 2007-09-04 | 2008-03-05 | $7700.00 | Window Closed / Lapsed |