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US5401847A Expired / Lapsed US ⏱️ 0.0 years remaining

DNA complexes with dyes designed for energy transfer as fluorescent markers

Assignee: University of California, San Diego
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Filing: 1993-01-27
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Granted: 1995-03-28
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Expires: 2013-01-27
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Abstract

Abstract Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.

Inventors

  • 👤 Alexander N. Glazer
  • 👤 Scott C. Benson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 15:26
CPC Classifications
C; C07; C07D; C07D417/00; C07D417/14; C07D221/00; C07D221/02; C07D221/04; C07D221/06; C07D221/10; C07D221/12; C07D405/00; C07D405/02; C07D405/12; C07D417/02; C07D417/06; C09; C09B; C09B23/00; C09B23/02; C09B23/04; C12; C12Q; C12Q1/00; C12Q1/68; C12Q1/6813; C12Q1/6816; C12Q1/6818; G; G01; G01N; G01N27/00; G01N27/26; G01N27/416; G01N27/447; G01N27/44704; G01N27/44717; G01N27/44721; G01N27/44726; G01N27/44747

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 15 words
A fluorescent heteromultimer which is thiazole orange-thiazole blue dimer of formula 7 of FIG. 2.
Claim 2
Dependent Claim 15 words
A fluorescent heteromultimer which is thiazole orange-thiazole blue dimer of formula 7 of FIG. 2.
Claim 3
Dependent Claim 14 words
A fluorescent heteromultimer which is thiazole orange-ethidium dimer of formula 11 of FIG. 3.
Claim 4
Dependent Claim 14 words
A fluorescent heteromultimer which is thiazole orange-ethidium dimer of formula 11 of FIG. 3.

References Cited (Backward Citations)

US4737454A Cited
US4883867A Cited
US4957870A Cited
US5047321A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1998-03-27 1998-09-26 1999-03-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2002-03-27 2002-09-26 2003-03-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2006-03-27 2006-09-26 2007-03-28 $7700.00 Window Closed / Lapsed

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