Mixing and delivering system

Claim 1

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a first container having a fluid reservoir for containing the second component and an outlet assembly having a fluid outlet in fluid communication with said fluid reservoir and first flow control means for normally closing said fluid outlet, said first flow control means being movable into a fluid outlet opening position; (b) adding means for presenting the first component to the second component for intermixing therewith, comprising: (i) a support upon which the first component is removably affixed; (ii) a second container for containing said support, said second container having a plug receiving chamber; and (iii) connector means for directly connecting said second container to said outlet assembly of said first container so that said support can be exposed to fluid flowing out of said fluid outlet of said container; and (c) second flow control means for controlling the flow of fluid into said second container, said second flow control means comprising a closure plug engageable by said first flow control means as said second container is connected to said outlet assembly, to move said closure plug into said plug receiving chamber and simultaneously to move said first flow control means into said fluid outlet opening position whereby fluid can flow toward said adding means.

Claim 2

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a first container having a fluid reservoir for containing the second component and an outlet assembly having a fluid outlet in fluid communication with said fluid reservoir and first flow control means for normally closing said fluid outlet, said first flow control means being movable into a fluid outlet opening position; (b) adding means for presenting the first component to the second component for intermixing therewith, comprising: (i) a support upon which the first component is removably affixed; (ii) a second container for containing said support, said second container having a plug receiving chamber; and (iii) connector means for directly connecting said second container to said outlet assembly of said first container so that said support can be exposed to fluid flowing out of said fluid outlet of said container; and (c) second flow control means for controlling the flow of fluid into said second container, said second flow control means comprising a closure plug engageable by said first flow control means as said second container is connected to said outlet assembly, to move said closure plug into said plug receiving chamber and simultaneously to move said first flow control means into said fluid outlet opening position whereby fluid can flow toward said adding means.

Claim 9

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a flexible container having a fluid reservoir for containing the second liquid component and a fluid outlet assembly having a fluid outlet having first threads said fluid outlet being in fluid communication with said fluid reservoir and first flow control means for controlling fluid flow through said fluid outlet, said first flow control means comprising a closure assembly having a closure cap for closing said fluid outlet and a pintle connected to said closure cap, said closure cap being movable from a first fluid outlet closing position to a second fluid outlet opening position; (b) adding means for presenting the first component to the second component for intermixing therewith, comprising: (i) a support upon which the first component is removably affixed; (ii) a vial for containing said support said vial having second threads mateable with said first threads and a plug receiving chamber; and (iii) connector means for directly connecting said vial to said fluid outlet assembly of said flexible container so that said support is exposed to fluid flowing through said fluid outlet, said connector means comprising threads provided on said vial for threadable interconnection with threads provided proximate said fluid outlet of said flexible container; (c) second flow control means for controlling the flow of fluid into said vial, said second flow control means comprising a closure plug engageable by said pintle as said vial is connected to said fluid outlet assembly to move said closure plug from a first inlet closing position into an inlet opening position wherein said plug is moved into said plug receiving chamber and simultaneously to move said closure cap toward said second open position whereby the liquid contained within said flexible container can flow from said fluid reservoir into said vial containing said support.

Claim 10

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a flexible container having a fluid reservoir for containing the second liquid component and a fluid outlet assembly having a fluid outlet having first threads said fluid outlet being in fluid communication with said fluid reservoir and first flow control means for controlling fluid flow through said fluid outlet, said first flow control means comprising a closure assembly having a closure cap for closing said fluid outlet and a pintle connected to said closure cap, said closure cap being movable from a first fluid outlet closing position to a second fluid outlet opening position; (b) adding means for presenting the first component to the second component for intermixing therewith, comprising: (i) a support upon which the first component is removably affixed; (ii) a vial for containing said support said vial having second threads mateable with said first threads and a plug receiving chamber; and (iii) connector means for directly connecting said vial to said fluid outlet assembly of said flexible container so that said support is exposed to fluid flowing through said fluid outlet, said connector means comprising threads provided on said vial for threadable interconnection with threads provided proximate said fluid outlet of said flexible container; (c) second flow control means for controlling the flow of fluid into said vial, said second flow control means comprising a closure plug engageable by said pintle as said vial is connected to said fluid outlet assembly to move said closure plug from a first inlet closing position into an inlet opening position wherein said plug is moved into said plug receiving chamber and simultaneously to move said closure cap toward said second open position whereby the liquid contained within said flexible container can flow from said fluid reservoir into said vial containing said support.

Claim 14

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a flexible container having top, bottom and side portions and including a fluid reservoir for containing the second component and a fluid outlet assembly connected to said bottom portion having a fluid outlet in fluid communication with said fluid reservoir, said fluid outlet assembly having internal threads and first flow control means for controlling fluid flow through said fluid outlet; (b) adding means for presenting the first component to the second liquid component for intermixing therewith, comprising: (i) a vial including an internal chamber having a fluid inlet and being provided with external threads mateable with said internal threads of said fluid outlet assembly, said vial having second flow control means for controlling the flow of liquid into said internal chamber, said second flow control means being operable by said first flow control means of said fluid outlet assembly; and (ii) adding means contained within said internal chamber said adding means comprising said first component and a presentation means for presenting said first component to said second component as said second component flows through said internal chamber, said presentation means comprising a porous support said first component being immobilized on said porous support and is removable therefrom using affinity chromotography techniques.

Claim 15

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a flexible container having top, bottom and side portions and including a fluid reservoir for containing the second component and a fluid outlet assembly connected to said bottom portion having a fluid outlet in fluid communication with said fluid reservoir, said fluid outlet assembly having internal threads and first flow control means for controlling fluid flow through said fluid outlet; (b) adding means for presenting the first component to the second liquid component for intermixing therewith, comprising: (i) a vial including an internal chamber having a fluid inlet and being provided with external threads mateable with said internal threads of said fluid outlet assembly, said vial having second flow control means for controlling the flow of liquid into said internal chamber, said second flow control means being operable by said first flow control means of said fluid outlet assembly; and (ii) adding means contained within said internal chamber said adding means comprising said first component and a presentation means for presenting said first component to said second component as said second component flows through said internal chamber, said presentation means comprising a porous support said first component being immobilized on said porous support and is removable therefrom using affinity chromotography techniques.

Claim 25

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a container having a fluid reservoir for containing the second liquid component and a fluid outlet assembly having a fluid outlet in fluid communication with said fluid reservoir and first flow control means for controlling fluid flow through said fluid outlet, said first flow control means comprising closure means for normally closing said fluid outlet, said closure means being movable from a first fluid outlet closing position to a second fluid outlet opening position; (b) adding means for presenting the first component to the second component for intermixing therewith, comprising: (i) a support upon which the first component is removably affixed; (ii) a vial for containing said support, said vial having a plug receiving chamber and being mateable with said fluid outlet assembly for moving said first flow control means toward said second fluid outlet opening position; and (iii) connector means for directly connecting said vial to said fluid outlet assembly of said flexible container so that said support can be exposed to fluid flowing through said fluid outlet; and (c) second flow control means for controlling the flow of fluid into said vial, said second flow control means comprising a closure plug and cooperating with said first flow control means to move said closure plug from a first inlet closing position into an inlet opening position wherein said plug is moved into said plug receiving chamber of said vial as said first flow control means is moved toward said second fluid outlet opening position, whereby the liquid contained within said container can flow from said fluid reservoir into said vial container said support.

Claim 26

An apparatus for controllably intermixing a first component and a second liquid component comprising: (a) a container having a fluid reservoir for containing the second liquid component and a fluid outlet assembly having a fluid outlet in fluid communication with said fluid reservoir and first flow control means for controlling fluid flow through said fluid outlet, said first flow control means comprising closure means for normally closing said fluid outlet, said closure means being movable from a first fluid outlet closing position to a second fluid outlet opening position; (b) adding means for presenting the first component to the second component for intermixing therewith, comprising: (i) a support upon which the first component is removably affixed; (ii) a vial for containing said support, said vial having a plug receiving chamber and being mateable with said fluid outlet assembly for moving said first flow control means toward said second fluid outlet opening position; and (iii) connector means for directly connecting said vial to said fluid outlet assembly of said flexible container so that said support can be exposed to fluid flowing through said fluid outlet; and (c) second flow control means for controlling the flow of fluid into said vial, said second flow control means comprising a closure plug and cooperating with said first flow control means to move said closure plug from a first inlet closing position into an inlet opening position wherein said plug is moved into said plug receiving chamber of said vial as said first flow control means is moved toward said second fluid outlet opening position, whereby the liquid contained within said container can flow from said fluid reservoir into said vial container said support.