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Patent US5340579A successfully refreshed from Google Patents.
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US5340579A Expired / Lapsed US ⏱️ 0.0 years remaining

Method of treating dermatological conditions

Assignee: Farmaka Srl
•
Filing: 1990-06-20
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Granted: 1994-08-23
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Expires: 2010-06-20
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Abstract

Abstract A method is provided for treating dermatological conditions by binding and blocking 5-a-dihydrotestosterone receptors comprising applying to the skin an effective amount of composition comprising: (a) from about 0.1% to about 2.0% by weight of mucopolysaccharides free of proteins and having a pH ranging from about 5 to 7.5 in aqueous solution, a rotary power between about to +15, and a sulfur content greater than 6%; (b) from about 1% to about 3% by weight of an aqueous extract of human umbilical cord free from sulfur and having a DH of from about 5 to about 7, a viscosity of 30° C. of from 10 to 25 centistokes, a hyaluronic acid titre of from about 500 to about 700 mg/dl, and an ash content of less than about 0.5%; (c) from about 0.05 to about 0.08% by weight of tetrahydrofurfuryl nicotinate; and (d) pharmaceutically and cosmetically acceptable vehicles and excipients. This method is particularly useful in treating dermatological conditions such as acne, wrinkles, lipodiystrophies, dermosclorosis, androgenic alopecia, hypertrichosis, and the like.

Inventors

  • 👤 Riccardo Casero, deceased

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 16:26
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/72; A61K8/73; A61K8/735; A61K8/96; A61K8/98; A61K8/981; A61K8/982; A61Q; A61Q7/00

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 176 words
A method for hydrating skin in a host in need thereof comprising administering to the skin of said host an effective amount of a composition comprising: (a) from about 0.1% to about 2.0% by weight of the total composition of mucopolysaccharides free of proteins and having a pH ranging from about 5 to about 7.5 in aqueous solution, a rotary power between about 0° and +15°, and a sulfur content about 6%; (b) from about 1% to about 3% by weight of the total composition of an aqueous extract of human umbilical cord wherein said extract produces a residue of about 2 to 3% at evaporation and is free from sulfur and having a pH of from about 5 to about 7, a viscosity at 30° C. of from 10 to 25 centistokes, a hyaluronic acid titre of from about 500 to about 700 mg/dl, and an ash content of about 0.1 to about 0.5%. (c) from about 0.05 to about 0.08% by weight of the total composition of tetrahydrofurfuryl nicotinate; and (d) pharmaceutically acceptable vehicles.
Claim 2
Independent Claim 176 words
A method for hydrating skin in a host in need thereof comprising administering to the skin of said host an effective amount of a composition comprising: (a) from about 0.1% to about 2.0% by weight of the total composition of mucopolysaccharides free of proteins and having a pH ranging from about 5 to about 7.5 in aqueous solution, a rotary power between about 0° and +15°, and a sulfur content about 6%; (b) from about 1% to about 3% by weight of the total composition of an aqueous extract of human umbilical cord wherein said extract produces a residue of about 2 to 3% at evaporation and is free from sulfur and having a pH of from about 5 to about 7, a viscosity at 30° C. of from 10 to 25 centistokes, a hyaluronic acid titre of from about 500 to about 700 mg/dl, and an ash content of about 0.1 to about 0.5%. (c) from about 0.05 to about 0.08% by weight of the total composition of tetrahydrofurfuryl nicotinate; and (d) pharmaceutically acceptable vehicles.
Claim 3
Dependent Claim 24 words
The method according to claim 1, wherein said mucopolysaccharides include hyaluronic acid which has a molecular weight between 2.5 million and 3 million daltons.
Claim 4
Dependent Claim 31 words
The method according to claim 1, wherein the composition has a weight ratio of said aqueous extract of human umbilical cord t said mucopolysaccharides ranges from about 1:1 to about 15:1.
Claim 5
Dependent Claim 33 words
The method according to claim 1, wherein the host is afflicted with a condition selected from the group consisting of acne, wrinkles, lipodystrophies, dermosclerosis, androgenetic alopecia, skin dystrophy, unaesthetisms, seborrheic alopecia, and hypertrichosis.
Claim 6
Dependent Claim 24 words
The method according to claim 4, wherein the host is afflicted with androgenetic and serborrheic alopecia and said composition is applied to the scalp.
Claim 7
Dependent Claim 16 words
The method according to claim 4, wherein the host is afflicted with skin dystrophy and unaesthetisms.

References Cited (Backward Citations)

GB200232A Cited
GB1198005A Cited
US3887703A Cited
GB1283892A Cited
US4303676A Cited
JPS56158706A Cited
US4504494A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-08-22 1998-02-21 1998-08-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-08-22 2002-02-21 2002-08-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-08-22 2006-02-21 2006-08-23 $7700.00 Window Closed / Lapsed

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