Abstract A flexible, organic bone matrix which is adapted for use during the in vivo repair, replacement or reformation of preselected portions of a mammalian or animal skeletal system comprising a continuous sheet of completely or partially demineralized natural bone, wherein the thickness of said sheet is such that the sheet has sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The matrix is ultimately resorbed by the body thereby eliminating the need for supplemental surgery to remove the matrix, as is presently necessary when other exogenous, membrane materials are used. A method f or the in vivo repair or replacement of a preselected section of a mammalian or animal skeletal system utilizing said matrix is also disclosed.
A flexible organic bone sheet for use during the in vivo replacement or reformation of preselected portions of an animal skeletal system consisting of a continuous sheet of demineralized natural bone, wherein the thickness of said sheet is less than about 1.5 millimeters, the sheet being capable of being bent from its original shape to conform to the configuration of a skeletal region to be repaired without damage to the sheet, said sheet being capable of inducing osteogenesis throughout its thickness.
Claim 2
Dependent Claim
81 words
A flexible organic bone sheet for use during the in vivo replacement or reformation of preselected portions of an animal skeletal system consisting of a continuous sheet of demineralized natural bone, wherein the thickness of said sheet is less than about 1.5 millimeters, the sheet being capable of being bent from its original shape to conform to the configuration of a skeletal region to be repaired without damage to the sheet, said sheet being capable of inducing osteogenesis throughout its thickness.
Claim 3
Dependent Claim
21 words
The organic bone matrix of claim 1, wherein the thickness of said sheet ranges from about 0.05 to about 1.5 millimeters.
Claim 4
Dependent Claim
21 words
The organic bone matrix of claim 1, wherein the thickness of said sheet ranges from about 0.7 to about 1.2 millimeters.