Patent US5276032A successfully refreshed from Google Patents.
US5276032A
Expired / Lapsed
US
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Vision aid and anesthetic composition
Assignee: Individual
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Filing: 1991-11-07
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Granted: 1994-01-04
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Expires: 2011-11-07
Abstract
Abstract A new visualizing and anesthetic composition and the process for the preparation thereof. The composition, generally as a gel, contains an effective amount of a topical anesthetic, an effective amount of a visualizing agent and a pharmaceutically acceptable gelling reservoir as a heat exchanger and/or a light transmitter. The composition is useful for topical application to a region of mammalian skin to supply visualization to a lesion therein and to anesthetize the region for a subsequent destructive therapy.
Inventors
- 👤 O. Newton King
- 👤 Henry W. Buck
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 18:24
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0014; A61K31/00; A61K31/185; A61K31/19; A61K31/21; A61K31/215; A61K31/235; A61K31/24; A61K31/245; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/535; A61K47/00; A61K47/30; A61K47/36; A61K47/38
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
167 words
A composition for topical application to a region of mammalian skin to supply visualization to a lesion therein and to anesthetize said region for a subsequent destructive therapy, said lesion being characterized as human papillomavirus related, said composition comprising: (a) from about 1% to about 20% by weight, based on total weight of said composition, of a topical anesthetic selected from the group consisting of lidocaine HCL, dyclonine HCL, pramoxine HCL, tetracaine HCL, dibucaine HCL, and cocaine HCL to impart local anesthesia around said region; (b) from about 0.1% to about 15% by weight, based upon total weight of said composition, of a visualizing agent selected from the group consisting of acetic acid and hydrochloric acid to visualize and recognize said lesion; (c) a pharmaceutical gelling reservoir comprising hydroxypropyl methylcellulose, glycerin, and water in an amount of about 0.5% to 10% by weight, based upon the total weight of said composition; and (d) said compositions having a pH in the range of about 2 to about 5.
Claim 2
Dependent Claim
167 words
A composition for topical application to a region of mammalian skin to supply visualization to a lesion therein and to anesthetize said region for a subsequent destructive therapy, said lesion being characterized as human papillomavirus related, said composition comprising: (a) from about 1% to about 20% by weight, based on total weight of said composition, of a topical anesthetic selected from the group consisting of lidocaine HCL, dyclonine HCL, pramoxine HCL, tetracaine HCL, dibucaine HCL, and cocaine HCL to impart local anesthesia around said region; (b) from about 0.1% to about 15% by weight, based upon total weight of said composition, of a visualizing agent selected from the group consisting of acetic acid and hydrochloric acid to visualize and recognize said lesion; (c) a pharmaceutical gelling reservoir comprising hydroxypropyl methylcellulose, glycerin, and water in an amount of about 0.5% to 10% by weight, based upon the total weight of said composition; and (d) said compositions having a pH in the range of about 2 to about 5.
Claim 3
Dependent Claim
44 words
The composition of claim 1 wherein said topical anesthetic is 1% by weight dyclonine HCL, said visualizing agent is 5% by weight of glacial acetic acid, said gelling reservoir is 1.5% by weight of hydroxypropyl methycellulose and 10% by weight of glycerin and water.
Claim 4
Dependent Claim
28 words
The composition of claim 2 wherein said glacial acetic acid is replaced with a sufficient amount of 0.1% of hydrochloric acid to reach a pH of about 3.
Claim 5
Dependent Claim
17 words
The composition of claim 2 wherein said topical anesthetic is about 5% by weight of lidocaine HCL.
Claim 6
Dependent Claim
17 words
The composition of claim 2 wherein said topical anesthetic is about 1% by weight of pramoxine HCL.
Claim 7
Dependent Claim
17 words
The composition of claim 2 wherein said topical anesthetic is about 2% by weight of tetracaine HCL.
Claim 8
Dependent Claim
17 words
The composition of claim 2 wherein said topical anesthetic is about 1% by weight of dibucaine HCL.
Claim 9
Dependent Claim
17 words
The composition of claim 2 wherein said topical anesthetic is about 10% by weight of cocaine HCL.
Claim 10
Dependent Claim
13 words
The composition of claim 4 wherein said hydroxypropyl methylcellulose is replaced with carboxymethylcellulose.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-01-03 | 1997-07-05 | 1998-01-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-01-03 | 2001-07-05 | 2002-01-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-01-03 | 2005-07-05 | 2006-01-04 | $7700.00 | Window Closed / Lapsed |