US4748022A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Topical composition
Assignee: Individual
•
Filing: 1986-12-09
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Granted: 1988-05-31
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Expires: 2006-12-09
Abstract
Abstract A composition and method of use for the treatment of pain and inflammation associated with lesions of the skin or mucus membrane, such as herpes simplex, herpes labialis, herpes progenitalis, chickenpox lesions, herpes genitalis, sensitivity of gingival tissue due to procedures for etching teeth with HCl, swollen gums, cheilosis, oral traumatic injuries, aphthous ulcer, by applying to the lesion an effective amount of a topical composition comprising diphenhydramine HCl, lidocaine HCl, aloe vera gel, propolis and sufficient base to raise the pH to 8-9.
Inventors
- 👤 John A. Busciglio
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 22:52
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/56; A61K35/63; A61K35/64; A61K35/644; A61K31/00; A61K31/16; A61K31/165; A61K31/167; A61K36/00; A61K36/18; A61K36/88; A61K36/886; A61K9/00; A61K9/0012; A61K9/0014; A61K9/0034; A61K9/0053; A61K9/0056; A61K9/06
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
71 words
A composition for the treatment of pain and inflammation associated with lesions of skin or mucous membrane comprising: lidocaine HCl: about 0.5 to 0.7 percent by weight; diphenhydramine HCl: about 0.06 to 0.09 percent by weight; aloe vera gel (100% pure): about 20 to 35 percent by weight; propolis 1-2 percent by weight and sufficient base to raise the pH of the final composition to 8-9 plus a suitable pharmaceutical excipient(s).
Claim 2
Dependent Claim
71 words
A composition for the treatment of pain and inflammation associated with lesions of skin or mucous membrane comprising: lidocaine HCl: about 0.5 to 0.7 percent by weight; diphenhydramine HCl: about 0.06 to 0.09 percent by weight; aloe vera gel (100% pure): about 20 to 35 percent by weight; propolis 1-2 percent by weight and sufficient base to raise the pH of the final composition to 8-9 plus a suitable pharmaceutical excipient(s).
Claim 3
Dependent Claim
13 words
The composition of claim 1 wherein the pharmaceutical excipient is a flavoring agent.
Claim 4
Dependent Claim
12 words
The composition of claim 1 wherein the pharmaceutical excipient is a preservative.
Claim 5
Dependent Claim
13 words
The composition of claim 1 wherein the pharmaceutical excipient is a sweetening agent.
Claim 6
Dependent Claim
12 words
The composition of claim 1 wherein the base is aluminum hydroxide gel.
Claim 7
Independent Claim
85 words
A method for the treatment of pain and inflammation associated with lesions of the skin or mucous membrane comprising applying to the lesion an effective amount of a composition comprising: lidocaine HCl: about 0.5 to 0.7 percent by weight; diphenhydramine HCl: about 0.06 to 0.09 percent by weight; aloe vera gel (about 99-100% pure): about 20 to 35 percent by weight; propolis: about 1-2 percent by weight; and sufficient base to raise the pH of the final composition to 8-9, plus a suitable pharmaceutical excipient(s).
Claim 8
Independent Claim
85 words
A method for the treatment of pain and inflammation associated with lesions of the skin or mucous membrane comprising applying to the lesion an effective amount of a composition comprising: lidocaine HCl: about 0.5 to 0.7 percent by weight; diphenhydramine HCl: about 0.06 to 0.09 percent by weight; aloe vera gel (about 99-100% pure): about 20 to 35 percent by weight; propolis: about 1-2 percent by weight; and sufficient base to raise the pH of the final composition to 8-9, plus a suitable pharmaceutical excipient(s).
Claim 9
Dependent Claim
88 words
The method of claim 6 for the treatment of pain and inflammation associated with oral lesions of the mucous membrane comprising applying to the oral lesion an effective amount of a composition comprising: lidocaine HCl: about 0.5 to 0.7 percent by weight; diphenhydramine HCl: about 0.06 to 0.09 percent by weight; aloe vera gel (about 99-100% pure): about 20 to 35 percent by weight; propolis: about 1-2 percent by weight; and sufficient base to raise the pH of the final composition to 8-9, plus a suitable pharmaceutical excipient(s).
Claim 10
Dependent Claim
40 words
The method of claim 7 wherein the composition is applied to lesions in the oral cavity by taking an effective amount of the composition into the mouth, swishing around the oral cavity, holding for about two minutes and then expectorating.
Claim 11
Dependent Claim
23 words
The method of claim 6 wherein an effective amount of the composition is topically applied to lesions of the skin associated with chickenpox.
Claim 12
Dependent Claim
24 words
The method of claim 6 wherein an effective amount of the composition is typically applied to lesions of the skin associated with herpes genitalis.
References Cited (Backward Citations)
US3892853A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-05-31 | 1991-11-30 | 1992-05-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-05-31 | 1995-11-30 | 1996-05-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-05-31 | 1999-11-30 | 2000-05-31 | $7700.00 | Window Closed / Lapsed |