Patent US5167961A successfully refreshed from Google Patents.
US5167961A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for preparing high purity bone mineral
Assignee: Ed Geistlich Soehne AG fuer Chemische Industrie
•
Filing: 1989-06-02
•
Granted: 1992-12-01
•
Expires: 2009-06-02
Abstract
Abstract The invention provides a process for the preparation of high purity bone mineral wherein the organic matter is degraded by heating with ammonia or a primary amine, characterized in that the solubilized degradation products are extracted by washing with flowing water at temperature below 60° C., such heating with primary amine and washing steps optionally being repeated, whereby substantially all organic matter removable by these steps is removed, the bone mineral so treated being heated in air at temperatures between 250° C. and 600° C.
Inventors
- 👤 Heinz Lussi
- 👤 Peter Geistlich
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 11:39
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61L27/3604; A61L27/3608; A61L27/3641; A61L27/3645; A61L27/365; A61L27/3683; A61L27/3695; A61L27/50; A61L27/54; A61L2300/00; A61L2300/20; A61L2300/252; A61L2300/40; A61L2300/404; A61L2300/406; A61L2300/412; A61L2300/414; A61L2300/45; A61L2430/00; A61L2430/02; A61L2430/40; Y; Y10; Y10S; Y10S530/00; Y10S530/827; Y10S530/84
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
114 words
A process for the preparation of high purity bone mineral wherein the organic matter in degreased bone is degraded and solubilized by heating with ammonia or a primary amine, characterized in that the solubilized degradation products are extracted by washing with flowing water at temperatures below 60° C., such heating with primary amine and washing steps optionally being repeated, whereby substantially all organic matter removable by these steps is removed so as to provide bone mineral having an organic impurity content less than 150 parts per million and a protein content less than 135 parts per million, the bone mineral so treated being heated in air at temperatures between 250° C. and 600° C.
Claim 2
Dependent Claim
114 words
A process for the preparation of high purity bone mineral wherein the organic matter in degreased bone is degraded and solubilized by heating with ammonia or a primary amine, characterized in that the solubilized degradation products are extracted by washing with flowing water at temperatures below 60° C., such heating with primary amine and washing steps optionally being repeated, whereby substantially all organic matter removable by these steps is removed so as to provide bone mineral having an organic impurity content less than 150 parts per million and a protein content less than 135 parts per million, the bone mineral so treated being heated in air at temperatures between 250° C. and 600° C.
Claim 3
Dependent Claim
25 words
A process as claimed in claim 1 in which the primary amine is an aliphatic or alicyclic amine having one or more primary amino groups.
Claim 4
Dependent Claim
32 words
A process as claimed in claim 1 or claim 2 in which the bone is heated with the primary amine or ammonia at a temperature in the range 100° to 150° C.
Claim 5
Dependent Claim
23 words
A process as claimed in claim 1 or claim 2 in which said flowing water flows at 1 to 50 cm per hour.
Claim 6
Dependent Claim
23 words
A process as claimed in claim 1 or claim 2 in which the final heating is in the range 350° to 500° C.
References Cited (Backward Citations)
US2968593A
Cited
US4587268A
Cited
US4314380A
Cited
US4455256A
Cited
US4434094A
Cited
EP0147021A1
Cited
US4654464A
Cited
WO1986007265A1
Cited
WO1989001347A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-12-01 | 1996-06-01 | 1996-12-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-12-01 | 2000-06-01 | 2000-12-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-12-01 | 2004-06-01 | 2004-12-01 | $7700.00 | Window Closed / Lapsed |