US5160790A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Lubricious hydrogel coatings
Assignee: Medtronic Vascular Inc
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Filing: 1990-11-01
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Granted: 1992-11-03
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Expires: 2010-11-01
Abstract
Abstract A flexible, lubricious organic coating is formed by applying a mixture of an isocyanate, a polyol, polyvinylpyrrolidone (PVP), and carrier liquid to a surface to be coated. The carrier liquid is removed and the mixture reacted to form a lubricious, flexible coating, particularly suitable for use as a protective lubricious caoting on medical devices introduced into the body. The coating exhibits a significantly reduced coefficient of friction when exposed to water or aqueous solutions.
Inventors
- 👤 Richard K. Elton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:40
CPC Classifications
A; A61; A61L; A61L29/00; A61L29/08; A61L29/085; A61L29/14; C; C09; C09D; C09D139/00; C09D139/04; C09D139/06; C09D175/00; C09D175/04; A61L2400/00; A61L2400/10; C08; C08L; C08L75/00; C08L75/04; Y; Y10; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31507; Y10T428/31551; Y10T428/31554; Y10T428/31562; Y10T428/31565; Y10T428/31569; Y10T428/31573; Y10T428/31587
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
69 words
An article comprising a substrate on which is coated a hydrophilic, lubricious, organic coating comprising a crosslinked polyurethane and a polyvinylpyrrolidone, said crosslinked polyurethane formed from the reaction of an isocyanate and a polyol, said isocyanate containing at least two NCO groups per molecule and the polyol having at least two hydroxy groups per molecule, the sum of the average NCO functionality and the average hydroxy functionality exceeding 4.
Claim 2
Dependent Claim
69 words
An article comprising a substrate on which is coated a hydrophilic, lubricious, organic coating comprising a crosslinked polyurethane and a polyvinylpyrrolidone, said crosslinked polyurethane formed from the reaction of an isocyanate and a polyol, said isocyanate containing at least two NCO groups per molecule and the polyol having at least two hydroxy groups per molecule, the sum of the average NCO functionality and the average hydroxy functionality exceeding 4.
Claim 3
Dependent Claim
32 words
An article comprising a substrate on which is coated a coating in accordance with claim 1 wherein the polyvinylpyrrolidone has a number average molecular weight of from about 50,000 to 2.5 million.
Claim 4
Dependent Claim
28 words
An article comprising a substrate on which is coated a coating in accordance with claim 2 wherein the polyvinylpyrrolidone has a number average molecular weight of about 360,000.
Claim 5
Dependent Claim
32 words
An article comprising a substrate on which is coated a coating in accordance with claim 1 wherein the ratio by weight of the polyurethane to polyvinylpyrrolidone is from about 0.05 to 3.0.
Claim 6
Dependent Claim
27 words
An article comprising a substrate on which is coated a coating in accordance with claim 4 wherein the ratio by weight is from about 0.2 to 1.0.
Claim 7
Dependent Claim
27 words
An article comprising a substrate on which is coated a coating in accordance with claim 1 wherein the crosslinked polyurethane is formed in the presence of polyvinylpyrrolidone.
Claim 8
Dependent Claim
34 words
An article comprising a substrate on which is coated a coating in accordance with claim 1 wherein the stoichiometric ratio of total NCO groups to total hydroxy groups is from about 0.75 to 3.0.
Claim 9
Dependent Claim
34 words
An article comprising a substrate on which is coated a coating in accordance with claim 7 wherein the stoichiometric ratio of total NCO groups to total hydroxy groups is from about 1.1 to 1.3.
Claim 10
Dependent Claim
22 words
An organic substrate article having a hydrophilic coating comprising: an organic substrate, and the coating in accordance with claim 1 adhered thereto.
Claim 11
Dependent Claim
38 words
The article of claim 9 wherein the organic substrate is of a material selected from the group consisting of polyether block amides, polyurethanes, polyetherurethanes, polyester urethanes, natural rubber, synthetic rubber, latex rubber, polyester-polyether copolymers, polycarbonates and polyethylene terephthalates.
Claim 12
Dependent Claim
84 words
An article comprising an organic substrate and a hydrophilic, lubricious organic coating adhered thereto, said coating formed from the reaction on the surface of the substrate to be coated, of a mixture comprising an isocyanate, a polyol and polyvinylpyrrolidone in a carrier liquid to form a crosslinked polyurethane-polyvinylpyrrolidone coating, said isocyanate containing at least two NCO groups per molecule and the polyol having at least two hydroxy groups per molecule, the sum of the average NCO functionality and the average hydroxy functionality exceeding 4.
Claim 13
Dependent Claim
84 words
An article comprising an organic substrate and a hydrophilic, lubricious organic coating adhered thereto, said coating formed from the reaction on the surface of the substrate to be coated, of a mixture comprising an isocyanate, a polyol and polyvinylpyrrolidone in a carrier liquid to form a crosslinked polyurethane-polyvinylpyrrolidone coating, said isocyanate containing at least two NCO groups per molecule and the polyol having at least two hydroxy groups per molecule, the sum of the average NCO functionality and the average hydroxy functionality exceeding 4.
Claim 14
Dependent Claim
22 words
An article in accordance with claim 11 wherein the polyvinylpyrrolidone has a mean molecular weight of from about 50,000 to 2.5 million.
Claim 15
Dependent Claim
15 words
An article in accordance with claim 12 wherein the mixture contains a blend of polyvinylpyrrolidones.
Claim 16
Dependent Claim
55 words
An article in accordance with claim 11 wherein the isocyanate has at least two unreacted isocyanate groups per molecule and is selected from the group consisting of 2,4- and 2,6 Toluene Diisocyanate (TDI), 4,4'- diphenylmethonediisocyanate (MDI), other position isomers of MDI, polymeric versions of MDI, hexamethylene diisocyanate, and adducts and prepolymers prepared from the above.
Claim 17
Dependent Claim
33 words
An article in accordance with claim 11 wherein the polyol used is selected from the group consisting of castor oil and castor oil derivatives, modified polyether polyols, modified polyester polyols, and polyethylene glycols.
Claim 18
Dependent Claim
30 words
An article in accordance with claim 11 wherein the carrier liquid is a solvent selected from the group consisting of methylene chloride, dibromomethane, chloroform, dichloroethane, acetonitrile, dibromoethane and blends thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-11-03 | 1996-05-04 | 1996-11-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-11-03 | 2000-05-04 | 2000-11-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-11-03 | 2004-05-04 | 2004-11-03 | $7700.00 | Window Closed / Lapsed |