US5158955A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cosmetic composition comprising an ester of pyroglutamic acid
Assignee: Chesebrough Ponds USA Inc
•
Filing: 1991-12-10
•
Granted: 1992-10-27
•
Expires: 2011-12-10
Abstract
Abstract A preserved composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a special ester of pyroglutamic acid; and (ii) a cosmetically acceptable vehicle for the ester.
Inventors
- 👤 Walter T. Gibson
- 👤 Ian R. Scott
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 11:21
CPC Classifications
A; A61; A61Q; A61Q7/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/4906; A61K8/4913
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
143 words
A preserved composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth, which comprises: i. an effective amount of from 0.000i to 99% by weight of an ester of pyroglutamic acid having the structure (1): ##STR7## where R is an aryl group, or a C 1 to C 30 alkyl, branched alkyl or alkenyl group, or a mixture of said esters; and ii. from 1 to 99.999% by weight of a cosmetically acceptable vehicle for the ester; said effective amount of said ester being sufficient to increase hair growth in a rat, in accordance with the Rat Hair Growth Test, when said composition is applied topically thereto over a period of no more than three months, by at least 10% more than that obtainable using a control composition from which the said ester has been omitted.
Claim 2
Dependent Claim
143 words
A preserved composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth, which comprises: i. an effective amount of from 0.000i to 99% by weight of an ester of pyroglutamic acid having the structure (1): ##STR7## where R is an aryl group, or a C 1 to C 30 alkyl, branched alkyl or alkenyl group, or a mixture of said esters; and ii. from 1 to 99.999% by weight of a cosmetically acceptable vehicle for the ester; said effective amount of said ester being sufficient to increase hair growth in a rat, in accordance with the Rat Hair Growth Test, when said composition is applied topically thereto over a period of no more than three months, by at least 10% more than that obtainable using a control composition from which the said ester has been omitted.
Claim 3
Dependent Claim
29 words
The composition of claim 1, wherein the ester of pyroglutamic acid is chosen from those in structure (1) where R is a C 1 to C 20 alkyl group.
Claim 4
Dependent Claim
42 words
The composition of claim 2, wherein the ester is chosen from: pyroglutamic acid n-propyl ester pyroglutamic acid n-butyl ester pyroglutamic acid n-hexyl ester pyroglutamic acid n-heptyl ester pyroglutamic acid n-octyl ester pyroglutamic acid n-nonyl ester pyroglutamic acid n-decyl ester, and mixtures thereof.
Claim 5
Dependent Claim
13 words
The composition of claim 2, wherein the ester is: pyroglutamic acid n-hexyl ester.
Claim 6
Dependent Claim
13 words
The composition of claim 2, wherein the ester is: pyroglutamic acid n-octyl ester.
Claim 7
Dependent Claim
21 words
The composition of claim 1, wherein the ester of pyroglutamic acid forms from 0.01 to 20% by weight of the composition.
Claim 8
Dependent Claim
12 words
The composition of claim 1, wherein the vehicle acts as a preservative.
Claim 9
Dependent Claim
11 words
The composition of claim 1, which further comprises an activity enhancer.
Claim 10
Dependent Claim
14 words
The composition of claim 8, wherein the activity enhancer is another hair growth stimulant.
Claim 11
Dependent Claim
13 words
The composition of claim 9, wherein the other hair growth stimulant is minoxidil.
Claim 12
Dependent Claim
12 words
The composition of claim 1, which is a shampoo or hair conditioner.
References Cited (Backward Citations)
FR2122495A1
Cited
US3836665A
Cited
GB1377304A
Cited
GB1567496A
Cited
JPS57185209A
Cited
JPS60214744A
Cited
EP0277428A2
Cited
EP0295092A2
Cited
EP0342054A2
Cited
EP0342056A2
Cited
EP0342055A2
Cited
US4986982A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-10-27 | 1996-04-27 | 1996-10-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-10-27 | 2000-04-27 | 2000-10-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-10-27 | 2004-04-27 | 2004-10-27 | $7700.00 | Window Closed / Lapsed |