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Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation

Assignee: Alcon Research LLC
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Filing: 1990-05-31
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Granted: 1992-06-23
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Expires: 2010-05-31
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Abstract

Abstract Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.

Inventors

  • 👤 Stella M. Robertson
  • 👤 Herman M. Kunkle, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 12:31
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/557; A61K31/5575; A61K31/558; A61K31/56; A61K31/57; A61K38/00; A61K38/04; A61K38/12; A61K9/00; A61K9/0012; A61K9/0048

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 32 words
A method for treating corneal haze as an artifact of incident laser irradiation and resulting photoablation of corneal tissue comprising: applying to the affected eye, a therapeutically effective amount of a steroid.
Claim 2
Independent Claim 32 words
A method for treating corneal haze as an artifact of incident laser irradiation and resulting photoablation of corneal tissue comprising: applying to the affected eye, a therapeutically effective amount of a steroid.
Claim 3
Dependent Claim 10 words
The method of claim 1 wherein the steroid is dexamethasone.
Claim 4
Dependent Claim 20 words
The method of claim 1 wherein the steroid is present at a concentration of about 0.1 to 4.0 wt. %.
Claim 5
Dependent Claim 10 words
The method of claim 1 wherein the steroid is prednisolone.
Claim 6
Dependent Claim 10 words
The method of claim 1 wherein the steroid is fluoromethlone.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-06-23 1995-12-23 1996-06-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-06-23 1999-12-23 2000-06-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-06-23 2003-12-23 2004-06-23 $7700.00 Window Closed / Lapsed

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