Patent US5116623A successfully refreshed from Google Patents.
US5116623A
Expired / Lapsed
US
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Periodate iodophor composition with increased stability
Assignee: Becton Dickinson and Co
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Filing: 1991-01-22
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Granted: 1992-05-26
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Expires: 2011-01-22
Abstract
Abstract A germicidal iodophor composition is disclosed having improved long term stability, by controlling the pH of the composition and supplementing the elemental iodine with a source of periodate. The present invention comprises an iodophor composition comprising periodate and having a pH of about 4.5 or below. Processes for making the iodophors, as well as methods for killing bacteria on a substrate using these germicidal iodophor compositions are also disclosed.
Inventors
- 👤 Mohammad A. Khan
- 👤 John F. Moellmer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:31
CPC Classifications
A; A61; A61K; A61K33/00; A61K33/18; A61K33/40
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
82 words
An aqueous iodophor composition comprising: elemental iodine in a germicidally effective amount of about 0.5-1.25%; about 0.01-0.3% of periodate which maintains the level of elemental iodine by oxidation; said composition having a pH of below about 4.5; wherein said elemental iodine is maintained at a level of about 0.5%-1.25% by weight and wherein the percentage of iodine in the composition aged for 20 weeks at 52° C. and irradiated at 2.5 Mrads is higher than in the same composition not containing periodate.
Claim 2
Dependent Claim
82 words
An aqueous iodophor composition comprising: elemental iodine in a germicidally effective amount of about 0.5-1.25%; about 0.01-0.3% of periodate which maintains the level of elemental iodine by oxidation; said composition having a pH of below about 4.5; wherein said elemental iodine is maintained at a level of about 0.5%-1.25% by weight and wherein the percentage of iodine in the composition aged for 20 weeks at 52° C. and irradiated at 2.5 Mrads is higher than in the same composition not containing periodate.
Claim 3
Dependent Claim
13 words
An iodophor composition according to claim 1 wherein said pH is about 3-4.
Claim 4
Dependent Claim
14 words
An iodophor composition according to claim 1 wherein said composition comprises about 0.1-0.3% periodate.
Claim 5
Dependent Claim
23 words
An iodophor composition according to claim 1 comprising at least 1.1% elemental iodine, about 0.15-0.25% periodate, and a pH of up to 4.0.
Claim 6
Dependent Claim
14 words
An iodophor composition according to claim 4 further comprising a detergent and a surfactant.
Claim 7
Dependent Claim
93 words
A process for preparing an aqueous iodophor comprising the steps of: mixing water with a source of elemental iodine sufficient to establish a level of elemental iodine of about 0.5-1.25%; adding about 0.01-0.3% periodate to said mixture; adjusting the pH of said composition to about 4.5 or below; wherein said elemental iodine is maintained at a level of about 0.5%-1.25% by weight and wherein the percentage of iodine in the composition aged for 20 weeks at 52° C. and irradiated at 2.5 Mrads is higher than in the same composition not containing periodate.
Claim 8
Dependent Claim
93 words
A process for preparing an aqueous iodophor comprising the steps of: mixing water with a source of elemental iodine sufficient to establish a level of elemental iodine of about 0.5-1.25%; adding about 0.01-0.3% periodate to said mixture; adjusting the pH of said composition to about 4.5 or below; wherein said elemental iodine is maintained at a level of about 0.5%-1.25% by weight and wherein the percentage of iodine in the composition aged for 20 weeks at 52° C. and irradiated at 2.5 Mrads is higher than in the same composition not containing periodate.
Claim 9
Dependent Claim
27 words
A process according to claim 6 wherein said periodate is added in the amount of about 0.15-0.25% by weight and said pH is adjusted to about 3-4.
Claim 10
Dependent Claim
17 words
A process according to claim 6 further comprising the step of irradiating said iodophor with gamma radiation.
Claim 11
Dependent Claim
17 words
A process according to claim 8 wherein said iodophor is irradiated with 1.5-4.0 Mrads of gamma radiation.
Claim 12
Dependent Claim
28 words
A process according to claim 8 further comprising the steps of adding at least one detergent, adding at least one surfactant, and adding hydrogen peroxide to said iodophor.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-05-26 | 1995-11-25 | 1996-05-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-05-26 | 1999-11-25 | 2000-05-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-05-26 | 2003-11-25 | 2004-05-26 | $7700.00 | Window Closed / Lapsed |