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US5106579A Expired / Lapsed US ⏱️ 0.0 years remaining

Membrane type artificial lung and method for manufacture thereof

Assignee: Terumo Corp
•
Filing: 1990-09-27
•
Granted: 1992-04-21
•
Expires: 2010-09-27
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Abstract

Abstract A membrane type artificial lung uses a gas-exchange membrane having at least the surface thereof for exposure to blood or the minute pores therein coated or blocked with a vinyl type copolymer having as one of the components thereof a vinyl monomer possessing a perfluoroalkyl side chain. The gas-exchange membrane of the artificial lung is manufactured by a method which comprises bringing at least the surface of the gas-exchange membrane for exposure to blood into contact with a solution of the vinyl type copolymer and subsequently vaporizing the solvent in the solution.

Inventors

  • 👤 Hiromichi Fukazawa
  • 👤 Kazuhiko Hagiwara

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 16:07
CPC Classifications
B; B01; B01D; B01D67/00; B01D67/0081; B01D67/0088; A; A61; A61L; A61L33/00; A61L33/06; A61L33/064; Y; Y10; Y10S; Y10S128/00; Y10S128/03; Y10S261/00; Y10S261/28

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 38 words
A gas-exchange membrane for an artificial lung, comprising a membrane having a surface coated with a vinyl type copolymer comprising a methacrylate type copolymer comprising a methacrylate monomer possessing a perfluoroalkyl side chain which is exposed to blood.
Claim 2
Dependent Claim 38 words
A gas-exchange membrane for an artificial lung, comprising a membrane having a surface coated with a vinyl type copolymer comprising a methacrylate type copolymer comprising a methacrylate monomer possessing a perfluoroalkyl side chain which is exposed to blood.
Claim 3
Dependent Claim 20 words
A gas-exchange membrane for an artificial lung according to claim 1, wherein said vinyl type copolymer is a block copolymer.
Claim 4
Dependent Claim 49 words
A gas-exchange membrane for an artificial lung according to claim 2, wherein the weight ratio of a polymer component formed of a vinyl monomer possessing a perfluoroalkyl side chain to a polymer component formed of another monomer of said block copolymer is in the range of 0.25 to 1.5.
Claim 5
Dependent Claim 28 words
A gas-exchange membrane for an artificial lung according to claim 1, wherein said perfluoroalkyl side chain is --Ch 2 CH 2 (CF 2 ) 7 CF 3 .
Claim 6
Dependent Claim 18 words
A gas-exchange membrane for an artificial lung according to claim 1, wherein said membrane is a porous membrane.
Claim 7
Dependent Claim 22 words
A gas-exchange membrane for an artificial lung according to claim 5, wherein said porous membrane is made of an olefin type resin.
Claim 8
Dependent Claim 18 words
A gas-exchange membrane for an artificial lung according to claim 6, wherein said membrane is made of polypropylene.
Claim 9
Dependent Claim 18 words
A gas-exchange membrane for an artificial lung according to claim 1, wherein said membrane is a homogeneous membrane.
Claim 10
Dependent Claim 20 words
A gas-exchange membrane for an artificial lung according to claim 8, wherein said homogeneous membrane is made of silicone rubber.
Claim 11
Dependent Claim 19 words
A gas-exchange membrane for an artificial lung according to claim 1, wherein said membrane is a hollow fiber membrane.
Claim 12
Dependent Claim 38 words
A gas-exchange membrane for an artificial lung according to claim 1, wherein said vinyl type copolymer comprises a vinyl monomer possessing a perfluoroalkyl side chain applied in a wall thickness in the range of 0.001 to 10 μm.
Claim 13
Dependent Claim 89 words
A gas-exchange membrane for an artificial lung comprising a porous membrane having a wall thickness in the range of 5 to 80 μm, a porosity in the range of 20 to 80%, and a pore diameter in the range of 0.01 to 5 μm, wherein said porous membrane comprises minute pores blocked with a vinyl type copolymer of a methacrylate type copolymer comprising a methacrylate monomer possessing a perfluoroalkyl side chain and said porous membrane is coated with said vinyl type copolymer on a side wall exposed to blood.
Claim 14
Dependent Claim 89 words
A gas-exchange membrane for an artificial lung comprising a porous membrane having a wall thickness in the range of 5 to 80 μm, a porosity in the range of 20 to 80%, and a pore diameter in the range of 0.01 to 5 μm, wherein said porous membrane comprises minute pores blocked with a vinyl type copolymer of a methacrylate type copolymer comprising a methacrylate monomer possessing a perfluoroalkyl side chain and said porous membrane is coated with said vinyl type copolymer on a side wall exposed to blood.
Claim 15
Dependent Claim 20 words
A gas-exchange membrane for an artificial lung according to claim 12, wherein said vinyl type copolymer is a block copolymer.
Claim 16
Dependent Claim 51 words
A gas-exchange membrane for an artificial lung according to claim 13, wherein the weight ratio of a polymer component formed of a vinyl monomer possessing a perfluoroalkyl side chain to a polymer component formed of another monomer of said vinyl type block copolymer is in the range of 0.25 to 1.5.
Claim 17
Dependent Claim 28 words
A gas-exchange membrane for an artificial lung according to claim 12, wherein said perfluoroalkyl side chain is --CH 2 CH 2 (CF 2 ) 7 CF 3 .
Claim 18
Dependent Claim 22 words
A gas-exchange membrane for an artificial lung according to claim 12, wherein said porous membrane is made of an olefin type resin.
Claim 19
Dependent Claim 18 words
A gas-exchange membrane for an artificial lung according to claim 16, wherein said membrane is made of polypropylene.
Claim 20
Dependent Claim 19 words
A gas-exchange membrane for an artificial lung according to claim 12, wherein said membrane is a hollow fiber membrane.
Claim 21
Dependent Claim 28 words
A gas-exchange membrane of an artificial lung according to claim 18, wherein said hollow fiber membrane has an inside diameter in the range of 100 to 1,000 μm.

References Cited (Backward Citations)

US4008047A Cited
US4210529A Cited
US4220543A Cited
US4239729A Cited
GB2072047A Cited
US4444662A Cited
US4374802A Cited
US4619897A Cited
GB2141752A Cited
EP0164025A2 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1995-04-21 1995-10-21 1996-04-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1999-04-21 1999-10-21 2000-04-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2003-04-21 2003-10-21 2004-04-21 $7700.00 Window Closed / Lapsed

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