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US4239729A Expired / Lapsed US ⏱️ 0.0 years remaining

Oxygenator

Assignee: Terumo Corp
•
Filing: 1979-06-01
•
Granted: 1980-12-16
•
Expires: 1999-06-01
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Abstract

Abstract An oxygenator comprises a cylindrical housing provided with inlet and outlet ports for oxygen, and a bundle of hollow fibers disposed within the housing. The porous hollow fibers are made of polyolefin resin, sized at 100 to 300μ in inner diameter and 10 to 50μ in wall thickness, and have an average pore size of 200 to 1,000A and porosity of 20 to 80%. The blood is allowed to flow through the hollow fibers and O 2 --CO 2 exchange is effected through the porous walls of the hollow fibers.

Inventors

  • 👤 Hiroshi Hasegawa
  • 👤 Hiromichi Fukasawa

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 00:30
CPC Classifications
B; B01; B01D; B01D63/00; B01D63/02; B01D63/021; B01D63/022; B01D63/0222; B01D63/0233; Y; Y10; Y10S; Y10S128/00; Y10S128/03

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 178 words
An oxygenator, comprising: an elongated hollow housing having a longitudinally extending axis; a bundle of porous hollow fibers made of polyolefin resin arranged within the housing in the axial direction thereof, each fiber having an inner diameter of 100 to 300μ, a wall thickness of 10 to 50μ, an average pore size of 200 to 1,000A and a porosity of 20 to 80%; an oxygen chamber formed between the outer surface of the fiber bundle and the inner surface of the housing; inlet and outlet oxygen ports extending through the wall of the housing so as to communicate with the oxygen chamber; partition walls supporting the end portions of the hollow fibers, separating the open ends of the hollow fibers from the oxygen chamber and defining the length of the oxygen chamber; and inlet and outlet blood ports communicating with the interior space of each of the hollow fibers; the hollow fibers having polar radicals introduced into at least the outer surfaces of the polyolefin resin of the hollow fiber at the portions supported by the partition walls.
Claim 2
Dependent Claim 178 words
An oxygenator, comprising: an elongated hollow housing having a longitudinally extending axis; a bundle of porous hollow fibers made of polyolefin resin arranged within the housing in the axial direction thereof, each fiber having an inner diameter of 100 to 300μ, a wall thickness of 10 to 50μ, an average pore size of 200 to 1,000A and a porosity of 20 to 80%; an oxygen chamber formed between the outer surface of the fiber bundle and the inner surface of the housing; inlet and outlet oxygen ports extending through the wall of the housing so as to communicate with the oxygen chamber; partition walls supporting the end portions of the hollow fibers, separating the open ends of the hollow fibers from the oxygen chamber and defining the length of the oxygen chamber; and inlet and outlet blood ports communicating with the interior space of each of the hollow fibers; the hollow fibers having polar radicals introduced into at least the outer surfaces of the polyolefin resin of the hollow fiber at the portions supported by the partition walls.
Claim 3
Dependent Claim 16 words
The oxygenator according to claim 1 wherein said elongated hollow housing is an elongated round-cylindrical housing.
Claim 4
Dependent Claim 20 words
The oxygenator according to claim 1, wherein the polyolefin resin is selected from the group consisting of polyethylene and polypropylene.
Claim 5
Dependent Claim 34 words
The oxygenator according to claim 1 or 3, wherein the housing is provided with a radially inwardly directed projection serving to fasten a central portion, in the lengthwise direction, of the hollow fiber bundle.
Claim 6
Dependent Claim 58 words
The oxygenator according to claim 4, wherein the loading density of the hollow fiber is 50 to 80% at the fastened portion, 30 to 60% at the outer faces of the partition walls and the loading density at the central portion of the housing is at least 1.1 times larger than those at the ends of the housing.
Claim 7
Dependent Claim 31 words
The oxygenator according to claim 1 or 3, wherein the hollow fibers have open ends, the inner surfaces and open ends of the hollow fibers being coated with a thrombus-preventing material.
Claim 8
Dependent Claim 28 words
The oxygenator according to claim 6, wherein the housing is provided with a radially inwardly directed projection serving to fasten a central portion of the hollow fiber bundle.
Claim 9
Dependent Claim 58 words
The oxygenator according to claim 7, wherein the loading density of the hollow fiber is 50 to 80% at the fastened portion, 30 to 60% at the outer faces of the partition walls and the loading density at the central portion of the housing is at least 1.1 times larger than those at the ends of the housing.
Claim 10
Dependent Claim 180 words
An oxygenator, comprising: an elongated hollow housing having a longitudinally extending axis; a bundle of porous hollow fibers made of polyolefin resin arranged within the housing in the axial direction thereof, each fiber having an inner diameter of 100 to 300μ, a wall thickness of 10 to 50μ, an average pore size of 200 to 1,000A and a porosity of 20 to 80%; an oxygen chamber formed between the outer surface of the fiber bundle and the inner surface of the housing; inlet and outlet oxygen ports extending through the wall of the housing so as to communicate with the oxygen chamber; partition walls supporting the end portions of the hollow fibers, separating the open ends of the hollow fibers from the oxygen chamber and defining the length of the oxygen chamber; inlet and outlet blood ports communicating with the interior space of each of the hollow fibers; and a radially inwardly directed projection provided on an inner wall of the housing for fastening a central portion, in the lengthwise direction, of the hollow fiber bundle relative to the housing.
Claim 11
Dependent Claim 180 words
An oxygenator, comprising: an elongated hollow housing having a longitudinally extending axis; a bundle of porous hollow fibers made of polyolefin resin arranged within the housing in the axial direction thereof, each fiber having an inner diameter of 100 to 300μ, a wall thickness of 10 to 50μ, an average pore size of 200 to 1,000A and a porosity of 20 to 80%; an oxygen chamber formed between the outer surface of the fiber bundle and the inner surface of the housing; inlet and outlet oxygen ports extending through the wall of the housing so as to communicate with the oxygen chamber; partition walls supporting the end portions of the hollow fibers, separating the open ends of the hollow fibers from the oxygen chamber and defining the length of the oxygen chamber; inlet and outlet blood ports communicating with the interior space of each of the hollow fibers; and a radially inwardly directed projection provided on an inner wall of the housing for fastening a central portion, in the lengthwise direction, of the hollow fiber bundle relative to the housing.
Claim 12
Dependent Claim 16 words
The oxygenator according to claim 9 wherein said elongated hollow housing is an elongated round-cylindrical housing.
Claim 13
Dependent Claim 58 words
The oxygenator according to claim 9, wherein the loading density of the hollow fiber is 50 to 80% at the fastened portion, 30 to 60% at the outer faces of the partition walls and the loading density at the central portion of the housing is at least 1.1 times larger than those at the ends of the housing.
Claim 14
Dependent Claim 20 words
The oxygenator according to claim 9, wherein the polyolefin resin is selected from the group consisting of polyethylene and polypropylene.
Claim 15
Dependent Claim 31 words
The oxygenator according to claim 9 or 12, wherein the hollow fibers have open ends, the inner surfaces and open ends of the hollow fibers being coated with a thrombus-preventing material.

References Cited (Backward Citations)

FR1568130A Cited
US3579810A Cited
US3673612A Cited
US3855475A Cited
US3794468A Cited
US3934982A Cited
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SU577037A1 Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1983-12-16 1984-06-16 1984-12-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1987-12-16 1988-06-16 1988-12-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1991-12-16 1992-06-16 1992-12-16 $7700.00 Window Closed / Lapsed

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