US5104957A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
Assignee: AUTOGENESIS Inc
•
Filing: 1990-02-28
•
Granted: 1992-04-14
•
Expires: 2010-02-28
Abstract
Abstract The present invention provides a biologically compatible collagenous reaction product comprising ethylenically unsaturated or polymeric substituted collagen, the monomeric substituents being essentially free of nitrogen, e.g., methacrylate styrene, polyvinyl, ethylene. The collagenous reaction product can be polymerized, e.g., by exposure to UV irradiation, chemical agents or atmospheric oxygen, and molded to form useful medical implant articles. Methods of preparation are also provided.
Inventors
- 👤 Charles D. Kelman
- 👤 Dale P. DeVore
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 12:44
CPC Classifications
C; C08; C08F; C08F289/00; A; A61; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/24; A61L27/36; G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; A61F; A61F2310/00; A61F2310/00005; A61F2310/00365
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
54 words
A biologically compatible collagenous reaction product comprising collagen reacted with an acylating agent selected from the group consisting of glutaric anhydride, succinic anhydride, and maleic anhydride and at least one other acylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene/maleic anhydride copolymer, styrene/maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 2
Dependent Claim
54 words
A biologically compatible collagenous reaction product comprising collagen reacted with an acylating agent selected from the group consisting of glutaric anhydride, succinic anhydride, and maleic anhydride and at least one other acylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene/maleic anhydride copolymer, styrene/maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 3
Dependent Claim
41 words
A biologically compatible collagenous reaction product according to claim 1 comprising collagen reacted with glutaric anhydride and at least one member of the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene/maleic anhydride copolymer, styrene/maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 4
Dependent Claim
34 words
The collagenous reaction product according to claim 1, wherein said collagen is selected from the group consisting of purified Type I collagen, Type IV collagen, Type III collagen, intact collagen-rich tissue and combinations thereof.
Claim 5
Dependent Claim
15 words
The collagenous reaction product according to claim 3, wherein said collagen comprises Type I collagen.
Claim 6
Dependent Claim
18 words
The collagenous reaction product according to claim 4, wherein said Type I collagen is derived from bovine tissue.
Claim 7
Dependent Claim
18 words
The collagenous reaction product according to claim 4, wherein said Type I collagen is derived from human tissue.
Claim 8
Dependent Claim
34 words
A biologically compatible collagenous reaction product comprising collagen reacted with at least one member of the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene/maleic anhydride copolymer, styrene/maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 9
Dependent Claim
34 words
A biologically compatible collagenous reaction product comprising collagen reacted with at least one member of the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene/maleic anhydride copolymer, styrene/maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Claim 10
Dependent Claim
34 words
The collagenous reaction product according to claim 7, wherein said collagen is selected from the group consisting of purified Type I collagen, Type IV collagen, Type III collagen, intact collagen-rich tissue and combinations thereof.
Claim 11
Dependent Claim
15 words
The collagenous reaction product according to claim 8, wherein said collagen comprises Type I collagen.
Claim 12
Dependent Claim
18 words
The collagenous reaction product according to claim 9, wherein said Type I collagen is derived from bovine tissue.
Claim 13
Dependent Claim
18 words
The collagenous reaction product according to claim 9, wherein said Type I collagen is derived from human tissue.
Claim 14
Dependent Claim
21 words
A polymerized biologically compatible collagenous reaction product useful to form medical implant articles comprising the collagenous reaction product of claim 1.
Claim 15
Dependent Claim
34 words
The polymerized reaction product according to claim 12, wherein said collagen is selected from the group consisting of purified Type I collagen, Type IV collagen, Type III collagen, intact collagen-rich tissue and combinations thereof.
Claim 16
Dependent Claim
15 words
The polymerized reaction product according to claim 13, wherein said collagen comprises Type I collagen.
Claim 17
Dependent Claim
18 words
The polymerized reaction product according to claim 14, wherein said Type I collagen is derived from bovine tissue.
Claim 18
Dependent Claim
18 words
The polymerized reaction product according to claim 14, wherein said Type I collagen is derived from human tissue.
Claim 19
Dependent Claim
28 words
The polymerized reaction product according to claim 12, wherein said product has been polymerized by exposure to ultraviolet irradiation, chemical agents, atmospheric oxygen or combinations of the foregoing.
Claim 20
Dependent Claim
21 words
A polymerized biologically compatible collagenous reaction product useful to form medical implant articles comprising the collagenous reaction product of claim 7.
Claim 21
Dependent Claim
34 words
The polymerized reaction product according to claim 18, wherein said collagen is selected from the group consisting of purified Type I collagen, Type IV collagen, Type III collagen, intact collagen-rich tissue and combinations thereof.
Claim 22
Dependent Claim
15 words
The polymerized reaction product according to claim 19, wherein said collagen comprises Type I collagen.
Claim 23
Dependent Claim
18 words
The polymerized reaction product according to claim 20, wherein said Type I collagen is derived from bovine tissue.
Claim 24
Dependent Claim
18 words
The polymerized reaction product according to claim 20, wherein said Type I collagen is derived from human tissue.
Claim 25
Dependent Claim
28 words
The polymerized reaction product according to claim 19, wherein said product has been polymerized by exposure to ultraviolet irradiation, chemical agents, atmospheric oxygen or combinations of the foregoing.
References Cited (Backward Citations)
US2948706A
Cited
US3453222A
Cited
US4021245A
Cited
US3949073A
Cited
US4233360A
Cited
US4488911A
Cited
US4215200A
Cited
US4264493A
Cited
US4223984A
Cited
US4268131A
Cited
US4264155A
Cited
US4349470A
Cited
US4260228A
Cited
US4563490A
Cited
US4427808A
Cited
US4452925A
Cited
US4388428A
Cited
WO1983000339A1
Cited
US4424208A
Cited
US4581030A
Cited
US4572832A
Cited
US4650616A
Cited
WO1987000001A1
Cited
US4687518A
Cited
JPH01297484A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-04-14 | 1995-10-14 | 1996-04-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-04-14 | 1999-10-14 | 2000-04-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-04-14 | 2003-10-14 | 2004-04-14 | $7700.00 | Window Closed / Lapsed |