US5084006A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Iontopheretic delivery device
Assignee: Alza Corp
•
Filing: 1990-03-30
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Granted: 1992-01-28
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Expires: 2010-03-30
Abstract
Abstract An iontophoretic agent delivery device having donor and counter electrodes comprised of either metal or a hydrophobic polymer loaded with a conductive filler is provided. The agent reservoir in the donor electrode assembly contains about 10 to 60 wt % hydrophobic polymer, about 10 to 60 wt % hydrophilic polymer, and up to 50% agent. Similarly, the electrolyte reservoir contains about 10 to 60 wt % hydrophobic polymer, about 10 to 60 wt % hydrophilic polymer, and up to 50% electrolyte. The agent reservoir, the electrolyte reservoir and the electrodes are preferably in the form of films which are laminated to one another. The hydrophobic polymer component in the agent/electrolyte reservoir prevents the reservoir from delaminating from the metal/hydrophobic polymer based electrode, even after hydration of the reservoirs.
Inventors
- 👤 Patrick J. Lew
- 👤 J. Richard Gyory
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 02:18
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/0404; A61N1/0408; A61N1/0428; A61N1/0448; A61N1/18; A61N1/20; A61N1/30; A61N1/0432; A61N1/0436
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
129 words
An electrically powered iontophoretic agent delivery device including a donor electrode assembly, a counter electrode assembly and a source of electrical power electrically connected to the donor electrode assembly and the counter electrode assembly, the donor electrode assembly comprising: a) an agent reservoir containing an agent, the agent reservoir adapted to be placed in agent transmitting relation with a body surface; and b) a donor electrode electrically connected to the source of electrical power, the donor electrode having a surface which is in contact with the agent reservoir; wherein the agent reservoir is comprised of about 10 to 60 wt. % of a hydrophilic polymer, about 10 to about 60 wt. % of a solid hydrophobic polymer which is heat fusible and up to about 50% of the agent.
Claim 2
Dependent Claim
129 words
An electrically powered iontophoretic agent delivery device including a donor electrode assembly, a counter electrode assembly and a source of electrical power electrically connected to the donor electrode assembly and the counter electrode assembly, the donor electrode assembly comprising: a) an agent reservoir containing an agent, the agent reservoir adapted to be placed in agent transmitting relation with a body surface; and b) a donor electrode electrically connected to the source of electrical power, the donor electrode having a surface which is in contact with the agent reservoir; wherein the agent reservoir is comprised of about 10 to 60 wt. % of a hydrophilic polymer, about 10 to about 60 wt. % of a solid hydrophobic polymer which is heat fusible and up to about 50% of the agent.
Claim 3
Dependent Claim
14 words
The device of claim 1, wherein the donor electrode is comprised of a metal.
Claim 4
Dependent Claim
18 words
The device of claim 2, wherein the metal is selected from the group consisting of silver and zinc.
Claim 5
Dependent Claim
18 words
The device of claim 1, wherein the donor electrode comprises a hydrophobic polymer matrix containing a conductive filler.
Claim 6
Dependent Claim
12 words
The device of claim 4, wherein the conductive filler comprises metal particles.
Claim 7
Dependent Claim
12 words
The device of claim 4, wherein the conductive filler comprises carbon fibers.
Claim 8
Dependent Claim
21 words
The device of claim 4, wherein the agent reservoir and the donor electrode are each in the form of a film.
Claim 9
Dependent Claim
18 words
The device of claim 7, wherein the donor electrode and the agent reservoir are laminated to one another.
Claim 10
Dependent Claim
18 words
The device of claim 7, wherein the films are adhered to one another with an ionically conductive adhesive.
Claim 11
Dependent Claim
15 words
The device of claim 1, wherein the hydrophobic polymer comprises an ethylene vinyl acetate copolymer.
Claim 12
Dependent Claim
11 words
The device of claim 1, wherein the hydrophilic polymer comprises polyvinylpyrrolidone.
Claim 13
Dependent Claim
95 words
The device of claim 1, wherein the counter electrode assembly includes a counter electrode electrically connected to the source of electrical power and an electrolyte reservoir adapted to be placed in electrolyte transmitting relation with the body surface, the counter electrode having a surface which is in contact with the electrolyte reservoir; wherein the electrolyte reservoir is comprised of about 10 to 60 wt. % of a hydrophilic polymer, about 10 to about 60 wt. % of a solid hydrophobic polymer which is heat fusible and up to about 50 wt. % of the electrolyte.
Claim 14
Dependent Claim
14 words
The device of claim 12, wherein the counter electrode is comprised of a metal.
Claim 15
Dependent Claim
18 words
The device of claim 13, wherein the metal is selected from the group consisting of silver and zinc.
Claim 16
Dependent Claim
19 words
The device of claim 12, wherein the counter electrode is comprised of a hydrophobic polymer containing a conductive filler.
Claim 17
Dependent Claim
12 words
The device of claim 15, wherein the conductive filler comprises metal particles.
Claim 18
Dependent Claim
12 words
The device of claim 15, wherein the conductive filler comprises carbon fibers.
Claim 19
Dependent Claim
21 words
The device of claim 15, wherein the counter electrode and the electrolyte reservoir are each in the form of a film.
Claim 20
Dependent Claim
18 words
The device of claim 18, wherein the counter electrode and the electrolyte reservoir are laminated to one another.
Claim 21
Dependent Claim
18 words
The device of claim 18, wherein the films are adhered to one another with an ionically conductive adhesive.
Claim 22
Dependent Claim
19 words
The device of claim 12, wherein the hydrophobic polymer in the electrolyte reservoir comprises an ethylene vinyl acetate copolymer.
Claim 23
Dependent Claim
15 words
The device of claim 12, wherein the hydrophilic polymer in the electrolyte reservoir comprises polyvinyl-pyrrolidone.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1995-01-27 | 1995-07-29 | 1996-01-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1999-01-27 | 1999-07-29 | 2000-01-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2003-01-27 | 2003-07-29 | 2004-01-28 | $7700.00 | Window Closed / Lapsed |