US5041580A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Novel binuclear platinum complex and antitumor agent comprising this complex as active ingredient
Assignee: Tsumura and Co
•
Filing: 1989-12-28
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Granted: 1991-08-20
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Expires: 2009-12-28
Abstract
Abstract Disclosed are a binuclear platinum complex including di-μ-sulfoacetato-bis[1,2-diaminocyclohexane-platinum (II)] and isomers thereof, and an antitumor agent comprising this complex as an effective ingredient. This complex has a high antitumor activity and lower adverse side effects such as nephrotoxicity.
Inventors
- 👤 Ken Miyamoto
- 👤 Yuichi Fujii
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 19:32
CPC Classifications
C; C07; C07F; C07F15/00; C07F15/0006; C07F15/0086; C07F15/0093; A; A61; A61P; A61P35/00
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
11 words
A binuclear platinum complex represented by the following formula I: ##STR2##
Claim 2
Dependent Claim
11 words
A binuclear platinum complex represented by the following formula I: ##STR2##
Claim 3
Dependent Claim
11 words
A binuclear platinum complex represented by the following formula II. ##STR3##
Claim 4
Dependent Claim
11 words
A binuclear platinum complex represented by the following formula II. ##STR3##
Claim 5
Dependent Claim
11 words
A binuclear platinum complex represented by the following formula III: ##STR4##
Claim 6
Dependent Claim
11 words
A binuclear platinum complex represented by the following formula III: ##STR4##
Claim 7
Dependent Claim
2 words
Di-μ-sulfoacetato-bis[(cis-diaminocyclohexane)platinum (II)].
Claim 8
Dependent Claim
2 words
Di-μ-sulfoacetato-bis[(cis-diaminocyclohexane)platinum (II)].
Claim 9
Dependent Claim
18 words
An antitumor agent comprising as an effective ingredient a binuclear platinum complex represented by the following formula: ##STR5##
Claim 10
Dependent Claim
18 words
An antitumor agent comprising as an effective ingredient a binuclear platinum complex represented by the following formula: ##STR5##
Claim 11
Dependent Claim
18 words
An antitumor agent comprising as an effective ingredient a binuclear platinum complex represented by the following formula: ##STR6##
Claim 12
Dependent Claim
18 words
An antitumor agent comprising as an effective ingredient a binuclear platinum complex represented by the following formula: ##STR6##
Claim 13
Dependent Claim
18 words
An antitumor agent comprising as an effective ingredient a binuclear platinum complex represented by the following formula: ##STR7##
Claim 14
Dependent Claim
18 words
An antitumor agent comprising as an effective ingredient a binuclear platinum complex represented by the following formula: ##STR7##
Claim 15
Dependent Claim
10 words
An antitumor agent comprising di-μ-sulfoacetato-bis-[(cis-diaminocyclohexane)platinum (II)] as an effective ingredient.
Claim 16
Dependent Claim
10 words
An antitumor agent comprising di-μ-sulfoacetato-bis-[(cis-diaminocyclohexane)platinum (II)] as an effective ingredient.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-08-19 | 1995-02-18 | 1995-08-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-08-19 | 1999-02-18 | 1999-08-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-08-19 | 2003-02-18 | 2003-08-20 | $7700.00 | Window Closed / Lapsed |