Patent US5037637A successfully refreshed from Google Patents.
US5037637A
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Antibacterial antiplaque, anticalculus oral composition
Assignee: Colgate Palmolive Co
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Filing: 1989-12-08
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Granted: 1991-08-06
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Expires: 2009-12-08
Abstract
Abstract An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-tricholoro-21-hydroxydiphenyl ether (Triclosan).
Inventors
- 👤 Abaul Gaffar
- 👤 Nuran Nabi
- 👤 Brian S. Jannone
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 08:19
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/24; A61K8/30; A61K8/33; A61K8/34; A61K8/347; A61K8/40; A61K8/42; A61K8/72; A61K8/81; A61K8/8164
Claims Analysis
Total Claims: 28
Claim 1
Independent Claim
61 words
An oral composition comprising in an orally acceptable vehicle, an effective anticalculus amount of material comprising at least one wholly or partially neutralized alkali metal or ammonium tripolyphosphate or hexametaphosphate salt as anticalculus agent and an effective antiplaque amount of a substantially water insoluble noncationic antibacterial agent selected from the group consisting of halogenated diphenyl ethers, phenolic compounds and halogenated carbanilides.
Claim 2
Dependent Claim
61 words
An oral composition comprising in an orally acceptable vehicle, an effective anticalculus amount of material comprising at least one wholly or partially neutralized alkali metal or ammonium tripolyphosphate or hexametaphosphate salt as anticalculus agent and an effective antiplaque amount of a substantially water insoluble noncationic antibacterial agent selected from the group consisting of halogenated diphenyl ethers, phenolic compounds and halogenated carbanilides.
Claim 3
Dependent Claim
15 words
The oral composition claimed in claim 1 wherein sodium tripolyphosphate is present as anticalculus agent.
Claim 4
Dependent Claim
40 words
The oral composition claimed in claim 1 wherein said at least one salt is present in amount of about 0.1-7% by weight and said substantially water insoluble nonocationic antibacterial agent is present in an amount of about 0.01-5% by weight.
Claim 5
Dependent Claim
16 words
The oral composition claimed in claim 3 wherein said antibacterial agent is a halogenated diphenyl ether.
Claim 6
Dependent Claim
15 words
The oral composition claimed in claim 4 wherein said halogenated diphenyl ether is 2,4,4'-trichloro-2-hydroxy-diphenyl ether.
Claim 7
Dependent Claim
15 words
The oral composition claimed in claim 3 wherein said antibacterial agent is a phenolic compound.
Claim 8
Dependent Claim
17 words
The oral composition claimed in claim 6 wherein said phenolic compound is resorcinol or a derivative thereof.
Claim 9
Dependent Claim
14 words
The oral composition claimed in claim 7 wherein said phenolic compound is hexyl resorcinol.
Claim 10
Dependent Claim
85 words
The oral composition claimed in claim 3 wherein there is present for the purpose of inhibiting hydrolysis of P--O--P bonds in said polyphosphate salts by phosphatase enzymes in saliva to orthophosphates which are relatively ineffective as inhibitors of hydroxyapatite formation, an amount of a fluoride ion source sufficient to supply 25 ppm. to 2,000 ppm. of fluoride ions and 0.05% to 3% of a water-soluble alkali metal or ammonium synthetic anionic linear polymeric polycarboxylate salt having a molecular weight of about 1,000 to about 1,000,000.
Claim 11
Dependent Claim
68 words
The oral composition claimed in claim 9 wherein said fluoride ion source is sodium fluoride and amount sufficient to supply 300 ppm. to 2,000 ppm. of fluoride ions and said polycarboxylate salt is about 0.1 to 2% of a water soluble alkali metal or ammonium salt of a copolymer of vinyl methyl ether and maleic acid or anhydride having a molecular weight of about 30,000 to about 500,000.
Claim 12
Dependent Claim
15 words
The oral composition claimed in claim 3 wherein sodium tripolyphosphate is present as anticalculus agent.
Claim 13
Dependent Claim
14 words
The oral composition claimed in claim 11 wherein said antibacterial agent comprises 2,4,4'-trichloro-2-hydroxydiphenyl ether.
Claim 14
Dependent Claim
15 words
The oral composition claimed in claim 3 wherein sodium hexametaphosphate is present as anticalculus agent.
Claim 15
Dependent Claim
14 words
The oral composition claimed in claim 13 wherein said antibacterial agent comprises 2,4,4'-trichloro-2-hydroxydiphenyl ether.
Claim 16
Dependent Claim
30 words
The oral composition claimed in claim 1 wherein said oral composition contains a dentally acceptable water-insoluble polishing agent and said oral compositions is a toothpowder, dental tablet, toothpaste or dentifrice.
Claim 17
Dependent Claim
50 words
The oral composition claimed in claim 15 wherein said oral composition contains about 10-80% by weight of a liquid phase comprising water and humectant, about 0.1-10% by weight a gelling agent and about 10-75% by weight of said polishing agent and said oral composition is a toothpaste or gel dentifrice.
Claim 18
Dependent Claim
16 words
The oral composition claimed in claim 16 wherein said polishing material is a silica polishing material.
Claim 19
Dependent Claim
27 words
The oral composition claimed in claim 15 wherein said oral composition contains about 70-99% by weight of said polishing material and said oral composition is a toothpowder.
Claim 20
Dependent Claim
41 words
The oral composition claimed in claim 1 wherein said oral composition contains about 90-99.9% by weight of a mixture of water and alcohol in a weight ratio of from about 1:1 to about 20:1 and said oral compositions is a mouthrinse.
Claim 21
Dependent Claim
12 words
The oral composition claimed in claim 19 wherein said alcohol is ethanol.
Claim 22
Dependent Claim
14 words
The oral composition claimed in claim 1 wherein said oral composition is a lozenge.
Claim 23
Dependent Claim
15 words
The oral composition claimed in claim 1 wherein said oral composition is a chewing gum.
Claim 24
Dependent Claim
15 words
The oral composition claimed in claim 1 wherein sodium hexametaphosphate is present as anticalculus agent.
Claim 25
Dependent Claim
71 words
The oral composition comprising about 10-75% by weight of a dentally acceptable water-insoluble polishing agent and an orally acceptable vehicle containing about 10-80% by weight of a liquid phase comprising water and humectant and about 0.1-10% by weight of a gelling agent, said oral composition being a dentifrice and there being present in said orally acceptable vehicle sodium tripolyphosphate anticalculus agent and an effective antiplaque amount of 2,4,4'-trichloro-2-hydroxy-diphenyl ether antibacterial agent.
Claim 26
Dependent Claim
71 words
The oral composition comprising about 10-75% by weight of a dentally acceptable water-insoluble polishing agent and an orally acceptable vehicle containing about 10-80% by weight of a liquid phase comprising water and humectant and about 0.1-10% by weight of a gelling agent, said oral composition being a dentifrice and there being present in said orally acceptable vehicle sodium tripolyphosphate anticalculus agent and an effective antiplaque amount of 2,4,4'-trichloro-2-hydroxy-diphenyl ether antibacterial agent.
Claim 27
Dependent Claim
35 words
The oral composition claimed in claim 24 wherein said sodium tripolypohosphate is present in amount of at least about 0.1-7% by weight and said antibacterial agent is present in amount of about 0.01-5% by weight.
Claim 28
Dependent Claim
87 words
The oral composition claimed in claim 25 wherein there is present for the purpose of inhibiting hydrolysis of P--O--P bonds in said polyphosphate salts by phosphatase enzymes in saliva to polyphosphates which are relatively ineffective as inhibitors of hydroxyapatite formation, an amount of a fluoride ion source sufficient to supply 25 ppm. to 2,000 ppm. of fluoride ions and 0.05% to 3% of a water-soluble alakli metal or ammonium salt of a copolymer of vinyl methyl ether and maleic anhydride having a molecular weight of about 70,000.
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1994-08-05 | 1995-02-04 | 1995-08-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-08-05 | 1999-02-04 | 1999-08-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-08-05 | 2003-02-04 | 2003-08-06 | $7700.00 | Window Closed / Lapsed |