US5034059A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Composition comprising octacalcium phosphate crystals and polypeptide
Assignee: Norian Corp
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Filing: 1989-02-17
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Granted: 1991-07-23
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Expires: 2009-02-17
Abstract
Abstract Octacalcium phosphate and hydroxyapatite are provided, where octacalcium phosphate is produced as novel single crystals and organized polycrystalline structures that are non-dense. The crystals serve as fibers, which find application in a wide variety of applications as well as coatings of prosthetic devices or other materials which may have physiological application.
Inventors
- 👤 Brent R. Constantz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 15:46
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/30; A61L27/32; A61L27/02; A61L27/12; C; C01; C01B; C01B25/00; C01B25/16; C01B25/26; C01B25/32; C01B25/325; C01B25/327; A61F; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; A61F2310/00389; A61F2310/00592; A61F2310/00796; Y; Y10; Y10S; Y10S128/00; Y10S128/08
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
102 words
A composition comprising octacalcium phosphate crystals and a polypeptide, said octacalcium phosphate crystals being substantially uniform single crystals and non-dense assemblages of polycrystalline structures in the form of spherulites, ropes (spaghetti) or fabrics, said crystals being produced by a method comprising: combining at a temperature in the range of about 60°-90° C. in stoichiometric amount by simultaneous addition, aqueous solutions of calcium cation and phosphate anion to an aqueous medium maintained at a pH in the range of about 4 to 7 until addition is complete to produce a dispersion containing octacalcium phosphate; and cooling said dispersion, whereby octacalcium phosphate crystals form.
Claim 2
Dependent Claim
102 words
A composition comprising octacalcium phosphate crystals and a polypeptide, said octacalcium phosphate crystals being substantially uniform single crystals and non-dense assemblages of polycrystalline structures in the form of spherulites, ropes (spaghetti) or fabrics, said crystals being produced by a method comprising: combining at a temperature in the range of about 60°-90° C. in stoichiometric amount by simultaneous addition, aqueous solutions of calcium cation and phosphate anion to an aqueous medium maintained at a pH in the range of about 4 to 7 until addition is complete to produce a dispersion containing octacalcium phosphate; and cooling said dispersion, whereby octacalcium phosphate crystals form.
Claim 3
Dependent Claim
11 words
A composition according to claim 1, wherein said polypeptide is collagen.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-07-22 | 1995-01-21 | 1995-07-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-07-22 | 1999-01-21 | 1999-07-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-07-22 | 2003-01-21 | 2003-07-23 | $7700.00 | Window Closed / Lapsed |