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US5028440A
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Method of raising meat producing animals to increase lean tissue development
Assignee: Iowa State University Research Foundation Inc
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Filing: 1990-01-30
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Granted: 1991-07-02
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Expires: 2010-01-30
Abstract
Abstract A method is provided for raising meat producing domestic animals to increase lean tissue development. beta -hydroxcy- beta -methylbutyric acid or an edible salt thereof (HMB) is administered to the animals in an effective amount for a sufficient length of time to obtain a substantial increase in lean tissue weight. Feed compositions for use in practicing the method are also provided. The method and feed compositions are particularly adapted for use with ruminants, including beef cattle and lambs, since HMB is not subject to appreciable rumen destruction. The method can also be practiced with other domestic animals, including chickens, and turkeys.
Inventors
- 👤 Steven L. Nissen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 18:11
CPC Classifications
A; A23; A23K; A23K50/00; A23K50/70; A23K50/75; A23K20/00; A23K20/10; A23K20/105; A23K50/10; Y; Y10; Y10S; Y10S426/00; Y10S426/807
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
104 words
The method of raising meat producing domestic animals to increase lean tissue development as shown by muscle growth, said animals being selected from the group consisting of beef cattle, lambs, and poultry, comprising orally administering to said animals an effective amount of β-hydroxy-β-methylbutyric acid or an edible salt thereof (HMB) to promote lean tissue development as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said administration being continued for a sufficient length of time to obtain a substantial increase in lean tissue.
Claim 2
Independent Claim
104 words
The method of raising meat producing domestic animals to increase lean tissue development as shown by muscle growth, said animals being selected from the group consisting of beef cattle, lambs, and poultry, comprising orally administering to said animals an effective amount of β-hydroxy-β-methylbutyric acid or an edible salt thereof (HMB) to promote lean tissue development as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said administration being continued for a sufficient length of time to obtain a substantial increase in lean tissue.
Claim 3
Dependent Claim
25 words
The method of claim 1 in which the amount of said HMB on the same basis is within the range from 0.5 to 100 mg.
Claim 4
Dependent Claim
48 words
The method of claim 1 or claim 2 in which said HMB is administered by admixing with feed for said animals, and the admixed feed is fed to the animals on a regular repeated basis for an extended number of days while the animals are increasing in weight.
Claim 5
Independent Claim
99 words
The method of feeding beef cattle to increase lean tissue development as shown by muscle growth, comprising feeding to said beef cattle in admixture with a protein-containing feed an effective amount of an edible salt of β-hydroxy-β-methylbutyric acid (HMB) to promote lean tissue development of said beef cattle as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said feeding being continued on a daily basis for at least 30 days while said beef cattle are gaining weight.
Claim 6
Independent Claim
99 words
The method of feeding beef cattle to increase lean tissue development as shown by muscle growth, comprising feeding to said beef cattle in admixture with a protein-containing feed an effective amount of an edible salt of β-hydroxy-β-methylbutyric acid (HMB) to promote lean tissue development of said beef cattle as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said feeding being continued on a daily basis for at least 30 days while said beef cattle are gaining weight.
Claim 7
Dependent Claim
29 words
The method of claim 4 in which the amount of said HMB salt is Ca-HMB and on said basis is fed within the range from 0.5 to 100 mg.
Claim 8
Independent Claim
92 words
The method of feeding lambs to increase lean tissue development as evidenced by muscle growth, comprising feeding to said lambs in admixture with a protein-containing feed an effective amount of an edible salt of β-hydroxy-β-methylbutyric acid (HMB) to promote lean tissue development as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said feeding being continued on a daily basis for at least 15 days while said lambs are gaining weight.
Claim 9
Independent Claim
92 words
The method of feeding lambs to increase lean tissue development as evidenced by muscle growth, comprising feeding to said lambs in admixture with a protein-containing feed an effective amount of an edible salt of β-hydroxy-β-methylbutyric acid (HMB) to promote lean tissue development as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said feeding being continued on a daily basis for at least 15 days while said lambs are gaining weight.
Claim 10
Dependent Claim
33 words
The method of claim 6 in which said HMB is in the form of its calcium salt (Ca-HMB) and said effective amount of Ca-HMB is within the range from 0.5 to 100 mg.
Claim 11
Independent Claim
103 words
The method of raising poultry for meat production to increase the development of lean tissue as shown by muscle growth, said poultry being selected from the group consisting of chickens and turkeys, comprising feeding said poultry an effective amount of an edible salt of β-hydroxy-β-methylbutyric acid (HMB) to promote lean tissue development as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said feeding being continued on a daily basis for at least 10 days while said poultry are increasing in weight.
Claim 12
Independent Claim
103 words
The method of raising poultry for meat production to increase the development of lean tissue as shown by muscle growth, said poultry being selected from the group consisting of chickens and turkeys, comprising feeding said poultry an effective amount of an edible salt of β-hydroxy-β-methylbutyric acid (HMB) to promote lean tissue development as shown by muscle growth, said effective amount being within the range from 0.05 to 500 milligrams (mg) HMB (Ca-HMB basis) per kilogram (kg) of body weight per 24 hours, and said feeding being continued on a daily basis for at least 10 days while said poultry are increasing in weight.
Claim 13
Dependent Claim
34 words
The method of claim 8 in which said HMB is in the form of its calcium salt (Ca-HMB) and said HMB is fed in an amount from 0.5 to 100 mg on said basis.
Claim 14
Independent Claim
13 words
The method of claims 8 or 9 in which said poultry are chickens.
Claim 15
Independent Claim
13 words
The method of claims 8 or 9 in which said poultry are turkeys.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-07-01 | 1994-12-31 | 1995-07-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-07-01 | 1998-12-31 | 1999-07-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-07-01 | 2002-12-31 | 2003-07-02 | $7700.00 | Window Closed / Lapsed |