US5026554A
Expired / Lapsed
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Method of inhibiting fungal growth using squalene synthetase inhibitors
Assignee: Merck and Co Inc
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Filing: 1990-09-13
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Granted: 1991-06-25
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Expires: 2010-09-13
Abstract
Abstract This invention relates to a method of inhibiting fungal growth by employing an antifungal amount of a compound of formula (I): ##STR1##
Inventors
- 👤 Kenneth F. Bartizal
- 👤 Janet C. Onishi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 16:13
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/08; C12; C12P; C12P17/00; C12P17/16; C12P17/162
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
88 words
A method of inhibiting fungal growth comprising applying to the area where growth is to be controlled an antifungally effective amount of a compound of formula I:. ##STR6## wherein Z 1 , Z 2 , and Z 3 are each independently selected from (a) H; (b) C 1-5 alkyl; (c) C 1-5 alkyl substituted with a member of the group consisting of (i) phenyl, (ii) phenyl substituted with methyl, methoxy, halogen (Cl, Br, I, F) or hydroxy; or a pharmaceutically acceptable salt of a compound of formula (I).
Claim 2
Independent Claim
88 words
A method of inhibiting fungal growth comprising applying to the area where growth is to be controlled an antifungally effective amount of a compound of formula I:. ##STR6## wherein Z 1 , Z 2 , and Z 3 are each independently selected from (a) H; (b) C 1-5 alkyl; (c) C 1-5 alkyl substituted with a member of the group consisting of (i) phenyl, (ii) phenyl substituted with methyl, methoxy, halogen (Cl, Br, I, F) or hydroxy; or a pharmaceutically acceptable salt of a compound of formula (I).
Claim 3
Dependent Claim
33 words
A method for inhibiting fungal growth, in a living organism in need of such treatment comprising the oral, systemic, or parenteral administration of an antifungally effective amount of a compound of claim 1.
Claim 4
Dependent Claim
12 words
A method of claim 2 wherein the living organism is a mammal.
Claim 5
Dependent Claim
12 words
A method of claim 2 wherein the living organism is a bird.
Claim 6
Dependent Claim
12 words
A method of claim 2 wherein the living organism is a plant.
Claim 7
Dependent Claim
16 words
A method of claim 2 wherein the compound is selected from the group consisting of: ##STR7##
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-06-24 | 1994-12-24 | 1995-06-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-06-24 | 1998-12-24 | 1999-06-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-06-24 | 2002-12-24 | 2003-06-25 | $7700.00 | Window Closed / Lapsed |