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US5023554A Expired / Lapsed US ⏱️ 0.0 years remaining

Fringe field MRI

Assignee: CALIFORNIA A CORP OF CA, University of, Regents of
•
Filing: 1989-05-22
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Granted: 1991-06-11
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Expires: 2009-05-22
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Abstract

Abstract Extremely non-homogenous high but extremely intense high fringe magnetic fields are purposefully (and even advantageously) utilized for magnetic resonance imaging (including localization and spectroscopy) so as to better obtain advantages typically associated with ultra high field MRI. Static magnetic field gradients inherently included in such fringe fields are actively utilized in conjunction with suitable NMR RF nutation pulses so as to achieve volume-selective NMR data acquisition. Special arrangements of static electromagnets, magnetic gradient coils and/or RF coils may be used in conjunction with novel RF/gradient pulse sequences so as to elicit and acquire suitable MRI data.

Inventors

  • 👤 Zang-Hee Cho
  • 👤 Edward K. Wong, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 21:45
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/28; G01R33/38; G01R33/3806; G01R33/3808

Claims Analysis

Total Claims: 67
Claim 1
Independent Claim 71 words
A magnetic resonance imaging method comprising: generating a static, non-homogenous, magnetic fringe field having an intensity greater than 2 Tesla with a static magnetic gradient in excess of 2 Gauss/cm along a predetermined z-axis through an MRI image volume; and using said static magnetic gradient in conjunction with an NMR RF pulse during an MRI data acquisition pulse sequence to achieve volume-selective NMR nutation of nuclei within said MRI image volume.
Claim 2
Dependent Claim 71 words
A magnetic resonance imaging method comprising: generating a static, non-homogenous, magnetic fringe field having an intensity greater than 2 Tesla with a static magnetic gradient in excess of 2 Gauss/cm along a predetermined z-axis through an MRI image volume; and using said static magnetic gradient in conjunction with an NMR RF pulse during an MRI data acquisition pulse sequence to achieve volume-selective NMR nutation of nuclei within said MRI image volume.
Claim 3
Dependent Claim 48 words
A magnetic resonance imaging method as in claim 1 wherein said magnetic fringe field is generated by at least one solenoidal electromagnet and said fringe field and image volume are located at a position substantially removed from the central center region of the bore of said solenoidal electromagnet.
Claim 4
Dependent Claim 24 words
A magnetic resonance imaging method as in claim 2 wherein said position is within the bore but offset toward an end of the electromagnet.
Claim 5
Dependent Claim 23 words
A magnetic resonance imaging method as in claim 2 wherein said position is outside the bore and proximate an end of the electromagnet.
Claim 6
Dependent Claim 31 words
A magnetic resonance imaging method as in claim 1 wherein said magnetic fringe field and image volume is located at a position between the spaced-apart ends of a pair of electromagnets.
Claim 7
Dependent Claim 20 words
A magnetic resonance imaging method as in claim 1 wherein said fringe field has an intensity greater than 3 Tesla.
Claim 8
Dependent Claim 26 words
A magnetic resonance imaging method as in claim 1 wherein said fringe field has a static magnetic gradient in excess of 10 gauss/cm along said z-axis.
Claim 9
Dependent Claim 25 words
A magnetic resonance imaging method as in claim 1 wherein single quantum NMR responses are elicited from said image volume for said MRI data acquisition.
Claim 10
Dependent Claim 19 words
A magnetic resonance imaging method as in claim 1 wherein said using step utilizes at frequency modulated RF pulses.
Claim 11
Dependent Claim 29 words
A magnetic resonance imaging method as in claim 1 wherein said generating step utilizes at least one solenoidal, electromagnet having a bore of less than 60 centimeters in diameter.
Claim 12
Dependent Claim 35 words
A magnetic resonance imaging method as in claim 1 wherein said generating step utilizes at least one solenoidal electromagnet having a maximum bore diameter which is less than the minimum dimension of said image volume.
Claim 13
Dependent Claim 30 words
A magnetic resonance imaging method as in claim 1 wherein said MRI data acquisition pulse sequence utilizes pulsed magnetic gradient fields which are asymmetric with respect to said image volume.
Claim 14
Dependent Claim 161 words
A magnetic resonance imaging method for acquiring MRI image data from an image volume located within a non-homogeneous static magnetic field having a substantial static gradient with respect to a predetermined z-axis, said method comprising the steps of: (a) transmitting into said volume at least one RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective first NMR nutation of NMR nuclei within a selected sub-volume of said image volume; (b) generating at least one phase-encoding magnetic gradient pulse to phase-encode NMR nuclei within said sub-volume with respect to at least one further axis orthogonal to said z-axis; (c) transmitting into said volume at least one further RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective second NMR nutation of NMR nuclei within said selected sub-volume; and (d) thereafter recording NMR RF responses from said sub-volume to provide acquired MRI image data.
Claim 15
Dependent Claim 161 words
A magnetic resonance imaging method for acquiring MRI image data from an image volume located within a non-homogeneous static magnetic field having a substantial static gradient with respect to a predetermined z-axis, said method comprising the steps of: (a) transmitting into said volume at least one RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective first NMR nutation of NMR nuclei within a selected sub-volume of said image volume; (b) generating at least one phase-encoding magnetic gradient pulse to phase-encode NMR nuclei within said sub-volume with respect to at least one further axis orthogonal to said z-axis; (c) transmitting into said volume at least one further RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective second NMR nutation of NMR nuclei within said selected sub-volume; and (d) thereafter recording NMR RF responses from said sub-volume to provide acquired MRI image data.
Claim 16
Dependent Claim 32 words
A magnetic resonance imaging method as in claim 13 wherein during said transmitting steps (a) and (c) there is substantially no magnetic gradient present in said sub-volume except said static magnetic gradients.
Claim 17
Dependent Claim 31 words
A magnetic resonance imaging method as in claim 13 wherein, during at least step (b), a magnetic gradient field is utilized which is asymmetrically and non-homogeneously distributed within said image volume.
Claim 18
Dependent Claim 74 words
Magnetic resonance imaging apparatus comprising: means for generating a static, non-homogenous, magnetic fringe field having an intensity greater than 2 Tesla with a static magnetic gradient in excess of 2 Gauss/cm along a predetermined z-axis through an MRI image volume; and means for using said static magnetic gradient in conjunction with an NMR RF pulse during an MRI data acquisition pulse sequence to achieve volume-selective NMR nutation of nuclei within said MRI image volume.
Claim 19
Dependent Claim 74 words
Magnetic resonance imaging apparatus comprising: means for generating a static, non-homogenous, magnetic fringe field having an intensity greater than 2 Tesla with a static magnetic gradient in excess of 2 Gauss/cm along a predetermined z-axis through an MRI image volume; and means for using said static magnetic gradient in conjunction with an NMR RF pulse during an MRI data acquisition pulse sequence to achieve volume-selective NMR nutation of nuclei within said MRI image volume.
Claim 20
Dependent Claim 45 words
Magnetic resonance imaging apparatus as in claim 16 wherein said means for generating includes at least one solenoidal electromagnet and said fringe field and image volume are located at a position substantially removed from the central center region of the bore of said solenoidal electromagnet.
Claim 21
Dependent Claim 23 words
Magnetic resonance imaging apparatus as in claim 17 wherein said position is within the bore but offset toward an end of the electromagnet.
Claim 22
Dependent Claim 22 words
Magnetic resonance imaging apparatus as in claim 17 wherein said position is outside the bore and proximate an end of the electromagnet.
Claim 23
Dependent Claim 30 words
Magnetic resonance imaging apparatus as in claim 16 wherein said magnetic fringe field and image volume is located at a position between the spaced-apart ends of a pair of electromagnets.
Claim 24
Dependent Claim 19 words
Magnetic resonance imaging apparatus as in claim 16 wherein said fringe field has an intensity greater than 10 Tesla.
Claim 25
Dependent Claim 25 words
Magnetic resonance imaging apparatus as in claim 16 wherein said fringe field has a static magnetic gradient in excess of 10 gauss/cm along said z-axis.
Claim 26
Dependent Claim 31 words
Magnetic resonance imaging apparatus as in claim 16 wherein said means for using includes means for eliciting single quantum NMR responses are from said image volume for said MRI data acquisition.
Claim 27
Dependent Claim 21 words
Magnetic resonance imaging apparatus as in claim 16 wherein said means for using includes means for generating frequency modulated RF pulses.
Claim 28
Dependent Claim 29 words
Magnetic resonance imaging apparatus as in claim 16 wherein said means for generating includes at least one solenoidal, electromagnet having a bore of less than 50 centimeters in diameter.
Claim 29
Dependent Claim 35 words
Magnetic resonance imaging apparatus as in claim 16 wherein said means for generating includes at least one solenoidal electromagnet having a maximum bore diameter which is less than the minimum dimension of said image volume.
Claim 30
Dependent Claim 30 words
Magnetic resonance imaging apparatus as in claim 16 wherein said means for using includes means for generating pulsed magnetic gradient fields which are asymmetric with respect to said image volume.
Claim 31
Dependent Claim 165 words
Magnetic resonance imaging apparatus for acquiring MRI image data from an image volume located within a non-homogeneous static magnetic field having a substantial static gradient with respect to a predetermined z-axis, said apparatus comprising: (a) means for transmitting into said volume at least one RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective first NMR nutation of NMR nuclei within a selected sub-volume of said image volume; (b) means for generating at least one phase-encoding magnetic gradient pulse to phase-encode NMR nuclei within said sub-volume with respect to at least one further axis orthogonal to said z-axis; (c) means for transmitting into said volume at least one further RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective second NMR nutation of NMR nuclei within said selected sub-volume; and (d) means for thereafter recording NMR RF responses from said sub-volume to provide acquired MRI image data.
Claim 32
Dependent Claim 165 words
Magnetic resonance imaging apparatus for acquiring MRI image data from an image volume located within a non-homogeneous static magnetic field having a substantial static gradient with respect to a predetermined z-axis, said apparatus comprising: (a) means for transmitting into said volume at least one RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective first NMR nutation of NMR nuclei within a selected sub-volume of said image volume; (b) means for generating at least one phase-encoding magnetic gradient pulse to phase-encode NMR nuclei within said sub-volume with respect to at least one further axis orthogonal to said z-axis; (c) means for transmitting into said volume at least one further RF nutation pulse including a predetermined range of frequencies which, in conjunction with said substantial static gradient, produces volume-selective second NMR nutation of NMR nuclei within said selected sub-volume; and (d) means for thereafter recording NMR RF responses from said sub-volume to provide acquired MRI image data.
Claim 33
Dependent Claim 31 words
Magnetic resonance imaging apparatus as in claim 28 wherein during operation of said means for transmitting there is substantially no magnetic gradient present in said sub-volume except said static magnetic gradients.
Claim 34
Dependent Claim 52 words
Magnetic resonance imaging apparatus as in claim 28 further comprising: means for generating at least one compensating magnetic gradient pulse within said sub-volume with respect to said z-axis at times other than during operation of said means for transmitting to thereby provide some compensation for the inhomogeneity of said static magnetic fields.
Claim 35
Dependent Claim 41 words
Magnetic resonance imaging apparatus as in claim 28 further comprising: means for generating a further phase-encoding magnetic gradient pulse during said recording step to phase-encode nuclei within said sub-volume with respect to a still further axis also orthogonal to said z-axis.
Claim 36
Dependent Claim 40 words
Magnetic resonance imaging apparatus as in claim 28 wherein, during operation of at least said means for transmitting (b) means for generating a magnetic gradient field is utilized which gradient field is asymmetrically and non-homogeneously distributed within said image volume.
Claim 37
Dependent Claim 74 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations.
Claim 38
Dependent Claim 74 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations.
Claim 39
Dependent Claim 63 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRI image volume disposed within said non-homogenous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume.
Claim 40
Dependent Claim 63 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRI image volume disposed within said non-homogenous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume.
Claim 41
Dependent Claim 25 words
Magnetic resonance imaging apparatus as in claim 33 or 34 wherein the bore of each said electromagnet is substantially less than 1 meter in diameter.
Claim 42
Dependent Claim 24 words
Magnetic resonance imaging apparatus as in claim 33 or 34 wherein the bore of each said electromagnet is less than 50 centimeters in diameter.
Claim 43
Dependent Claim 28 words
Magnetic resonance imaging apparatus as in claim 33 wherein the bore of each said electromagnet is less in maximum diameter than the minimum dimension of said image volume.
Claim 44
Dependent Claim 84 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field is in excess of 4 Tesla.
Claim 45
Dependent Claim 84 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field is in excess of 4 Tesla.
Claim 46
Dependent Claim 84 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field is in excess of 10 Tesla.
Claim 47
Dependent Claim 84 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field is in excess of 10 Tesla.
Claim 48
Dependent Claim 87 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field has a static gradient in excess of 2 Gauss/cm.
Claim 49
Dependent Claim 87 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field has a static gradient in excess of 2 Gauss/cm.
Claim 50
Dependent Claim 87 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field has a static gradient in excess of 10 Gauss/cm.
Claim 51
Dependent Claim 87 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said fringe field has a static gradient in excess of 10 Gauss/cm.
Claim 52
Dependent Claim 127 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said driving means includes means for generating frequency modulated RF pulses and transmitting them into said image volume to volume-selectively effect NMR nutation of NMR nuclei within a selected sub-volume defined by the range of frequencies included in said RF pulse and a static magnetic field gradient included in said fringe field.
Claim 53
Dependent Claim 127 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said driving means includes means for generating frequency modulated RF pulses and transmitting them into said image volume to volume-selectively effect NMR nutation of NMR nuclei within a selected sub-volume defined by the range of frequencies included in said RF pulse and a static magnetic field gradient included in said fringe field.
Claim 54
Dependent Claim 116 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said magnetic gradient coils include magnetic gradient coil means asymmetrically located with respect to said image volume for producing an asymmetric gradient field along a predetermined axis within said image volume during predetermined portions of an MRI data acquisition pulse sequence.
Claim 55
Dependent Claim 116 words
Magnetic resonance imaging apparatus comprising: a pair of spaced-apart solenoidal electromagnets having an MRI image volume located between their respective bores within a non-homogeneous static magnetic fringe field; magnetic gradient coils and RF coils disposed about said image volume; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume while utilizing, at least in part, said non-homogeneous static field to effect volume-selective NMR nutations; wherein said magnetic gradient coils include magnetic gradient coil means asymmetrically located with respect to said image volume for producing an asymmetric gradient field along a predetermined axis within said image volume during predetermined portions of an MRI data acquisition pulse sequence.
Claim 56
Dependent Claim 73 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field is in excess of 4 Tesla.
Claim 57
Dependent Claim 73 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field is in excess of 4 Tesla.
Claim 58
Dependent Claim 73 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field is in excess of 10 Tesla.
Claim 59
Dependent Claim 73 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field is in excess of 10 Tesla.
Claim 60
Dependent Claim 76 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field has a static gradient in excess of 2 Gauss/cm.
Claim 61
Dependent Claim 76 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field has a static gradient in excess of 2 Gauss/cm.
Claim 62
Dependent Claim 76 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field has a static gradient in excess of 10 Gauss/cm.
Claim 63
Dependent Claim 76 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said fringe field has a static gradient in excess of 10 Gauss/cm.
Claim 64
Dependent Claim 116 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said driving means includes means for generating frequency modulated RF pulses and transmitting them into said image volume to volume-selectively effect NMR nutation of NMR nuclei within a selected sub-volume defined by the range of frequencies included in said RF pulse and a static magnetic field gradient included in said fringe field.
Claim 65
Dependent Claim 116 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRi image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said driving means includes means for generating frequency modulated RF pulses and transmitting them into said image volume to volume-selectively effect NMR nutation of NMR nuclei within a selected sub-volume defined by the range of frequencies included in said RF pulse and a static magnetic field gradient included in said fringe field.
Claim 66
Dependent Claim 105 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRI image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said magnetic gradient coils include magnetic gradient coil means asymmetrically located with respect to said image volume for producing an asymmetric gradient field along a predetermined axis within said image volume during predetermined portions of an MRI data acquisition pulse sequence.
Claim 67
Dependent Claim 105 words
Magnetic resonance imaging apparatus comprising: a solenoidal electromagnet producing a non-homogeneous static magnetic fringe field located off-center within its bore proximate one end thereof; magnetic gradient and RF coils disposed about an MRI image volume disposed within said non-homogeneous fringe static magnetic field; and driving and receiving means connected to said gradient and RF coils for acquiring MRI data from said image volume wherein said magnetic gradient coils include magnetic gradient coil means asymmetrically located with respect to said image volume for producing an asymmetric gradient field along a predetermined axis within said image volume during predetermined portions of an MRI data acquisition pulse sequence.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1994-06-10 1994-12-10 1995-06-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1998-06-10 1998-12-10 1999-06-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2002-06-10 2002-12-10 2003-06-11 $7700.00 Window Closed / Lapsed

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