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US5004546A
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Process for measuring stable-type glycated hemoglobin in a sample
Assignee: Tosoh Corp
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Filing: 1989-09-01
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Granted: 1991-04-02
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Expires: 2009-09-01
Abstract
Abstract A process for measuring the amount of stable-type glycated hemoglobin in a sample using high performance liquid chromatography, comprising heating a sample diluted with a hemolysis agent containing a reagent for the removal of unstable-type glycated hemoglobin to achieve the removal of the unstable-type glycated hemoglobin, and analyzing the sample by high performance liquid chromatography.
Inventors
- 👤 Hiroaki Takahashi
- 👤 Haruo Okada
- 👤 Katsuya Matsumoto
- 👤 Masuo Umino
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 04:18
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/04; G01N30/06; G01N30/12; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/721; G01N33/723; Y; Y10; Y10T; Y10T436/00; Y10T436/25; Y10T436/25125; Y10T436/25375; Y10T436/255
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
66 words
A process for measuring the amount of stable-type glycated hemoglobin in a sample using high performance liquid chromatography, comprising heating to a temperature of at least 45° C. a sample diluted with a hemolysis agent containing a reagent comprising potassium phthalate for the removal of unstable-type glycated hemoglobin to achieve the removal of the unstable-type glycated hemoglobin, and analyzing the sample by high performance liquid chromatography.
Claim 2
Dependent Claim
66 words
A process for measuring the amount of stable-type glycated hemoglobin in a sample using high performance liquid chromatography, comprising heating to a temperature of at least 45° C. a sample diluted with a hemolysis agent containing a reagent comprising potassium phthalate for the removal of unstable-type glycated hemoglobin to achieve the removal of the unstable-type glycated hemoglobin, and analyzing the sample by high performance liquid chromatography.
Claim 3
Dependent Claim
18 words
The process of claim 1, comprising heating said sample to a temperature between 45° C. and 70° C.
Claim 4
Dependent Claim
16 words
The process of claim 1, wherein said sample is a sample obtained from a human patient.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-04-01 | 1994-10-01 | 1995-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-04-01 | 1998-10-01 | 1999-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-04-01 | 2002-10-01 | 2003-04-02 | $7700.00 | Window Closed / Lapsed |