US4992533A
Expired / Lapsed
US
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Sulfated oligosaccharides and derivatives thereof
Assignee: Mect Corp
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Filing: 1989-09-27
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Granted: 1991-02-12
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Expires: 2009-09-27
Abstract
Abstract The present invention relates to sulfated oligosaccharides or their derivatives such as the following compound and being useful for diagnosing or treating diseases such as immunity-related diseases and mucopolysaccharide diseases. ##STR1## (M is an alkali metal).
Inventors
- 👤 Masanori Kobayashi
- 👤 Mamoru Sugimoto
- 👤 Kenkichi Tomita
- 👤 Yukishige Ito
- 👤 Tomoya Ogawa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 23:48
CPC Classifications
C; C07; C07H; C07H5/00; C07H5/08; C07H5/10; C07H13/00; C07H13/02; C07H13/04; C07H11/00; C07H15/00; C07H15/02; C07H15/04; C07H15/10; C07H15/18
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
210 words
Sulfated oligosaccharides or their derivatives having the following formula: ##STR62## wherein ○ R 1 =R 2 =C 6 H 5 CH 2 (Bn), ##STR63## (wherein X=a halogen atom) or ##STR64## ○ R 1 =R 2 =Bn, R 3 =NHAc (Ac=an acetyl group), R 4 =H, MP or SO 3 M (wherein M=an alkali metal) and ##STR65## ○ ##STR66## (wherein R 6 =Ac, Bn or H), R 2 =Bn, R 3 =NPhth, R 4 =MP and R 5 = ##STR67## ○ ##STR68## R 2 =Bn, R 3 =NPhth, R 4 =MP and R 5 =OH. ○ ##STR69## R 2 =Bn, R 3 =NPhth, R 4 =MP and R 5 =OAc, OH, ##STR70## (X is a halogen atom) or ##STR71## ○ ##STR72## [wherein R 7 =H or t-Bu(C 6 H 5 ) s Si-(TBDPS)] R 2 =Bn, R 3 =NPhth, R 4 =MP and ##STR73## ○ ##STR74## R 2 =Bn, R 3 =NPhth or NHAc, R 4 =MP and ##STR75## ○ ##STR76## (wherein R 8 =H or TBDPS), R 2 =Bn, R 3 =NHAc, R 4 =H and ##STR77## ○ ##STR78## (wherein M=an alkali metal), R 2 =Bn, R 3 =NHAc, R 4 =SO 3 M and ##STR79## and ○1 ##STR80## R 2 =Bn, R 3 =NPhth, R 4 =MP and ##STR81##
Claim 2
Dependent Claim
210 words
Sulfated oligosaccharides or their derivatives having the following formula: ##STR62## wherein ○ R 1 =R 2 =C 6 H 5 CH 2 (Bn), ##STR63## (wherein X=a halogen atom) or ##STR64## ○ R 1 =R 2 =Bn, R 3 =NHAc (Ac=an acetyl group), R 4 =H, MP or SO 3 M (wherein M=an alkali metal) and ##STR65## ○ ##STR66## (wherein R 6 =Ac, Bn or H), R 2 =Bn, R 3 =NPhth, R 4 =MP and R 5 = ##STR67## ○ ##STR68## R 2 =Bn, R 3 =NPhth, R 4 =MP and R 5 =OH. ○ ##STR69## R 2 =Bn, R 3 =NPhth, R 4 =MP and R 5 =OAc, OH, ##STR70## (X is a halogen atom) or ##STR71## ○ ##STR72## [wherein R 7 =H or t-Bu(C 6 H 5 ) s Si-(TBDPS)] R 2 =Bn, R 3 =NPhth, R 4 =MP and ##STR73## ○ ##STR74## R 2 =Bn, R 3 =NPhth or NHAc, R 4 =MP and ##STR75## ○ ##STR76## (wherein R 8 =H or TBDPS), R 2 =Bn, R 3 =NHAc, R 4 =H and ##STR77## ○ ##STR78## (wherein M=an alkali metal), R 2 =Bn, R 3 =NHAc, R 4 =SO 3 M and ##STR79## and ○1 ##STR80## R 2 =Bn, R 3 =NPhth, R 4 =MP and ##STR81##
Claim 3
Dependent Claim
24 words
A pure form of a sulfated oligosaccharide having the following formula: ##STR82## wherein M is an alkali metal and Ac is an acetyl group.
Claim 4
Dependent Claim
24 words
A pure form of a sulfated oligosaccharide having the following formula: ##STR82## wherein M is an alkali metal and Ac is an acetyl group.
References Cited (Backward Citations)
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