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US4675392A Expired / Lapsed US ⏱️ 0.0 years remaining

Glycosides

Assignee: CARBOHYDRATES INTERNATIONAL A JOINT STOCK Co SWEDEN AB
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Filing: 1984-11-21
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Granted: 1987-06-23
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Expires: 2004-11-21
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Abstract

Abstract An O-glycoside having the general formula: (sugar)n-O-(CH2)m-Hal wherein Hal is chlorine, bromine or iodine, m is an integer of 2-20 inclusive and n is an integer of 1 to 10, inclusive, with the proviso that when n=1 and m=2, the aldose is different from glucose; An O-glycoside having the general formula: (sugar)n-O-(CH2)m-S-R-R' wherein n is an integer of from 1-10, inclusive, m is an integer of from 2-20, inclusive, R is selected from the group consisting of alkyl having at most 25 carbon atoms and aryl and R' is selected from the group consisting of H, CHO, CH(OR')2, NO2, NH2, OH, SH, COOH, COOCH3, COOCH2CH3, CONHNH2 and CON3, wherein R'' is C1-4-alkyl; A glycoconjugate having the general formula: (sugar)n-O-(CH2)m-S-R-R'' wherein n is an integer of from 1-10, inclusive, m is an integer of from 2-20, inclusive, R is selected from the group consisting of alkyl having at most 25 carbon atoms and aryl and R'' constitutes a carrier; A bi-dentate O-glycoside having the general formula: [(sugar)n-O-(CH2)m-S-2R wherein m, n and R have the above meaning; and processes for their preparation.

Inventors

  • 👤 Jan Dahmen
  • 👤 Torbjorn Frejd
  • 👤 Goran Magnusson
  • 👤 Ghazi Noori

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 05:26
CPC Classifications
C; C07; C07H; C07H3/00; C07H3/06; A; A61; A61K; A61K39/00; A61K39/385; A61K2039/60; A61K2039/6031; A61K2039/6087

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 112 words
An O-glycoside having the general formula: (sugar).sub.n --O--(CH.sub.2).sub.m --S--R--R' wherein n is an integer of from 1-10, inclusive, m is 2, R is selected from the group consisting of alkyl having 1-25 carbon atoms and aryl and R' is selected from the group consisting of H, CHO, CH(OR") 2 , NO 2 , NH 2 , OH, SH, COOH, COOCH 3 , COOCH 2 CH 3 , CONHNH 2 and CON 3 , wherein R" is C 1-4 -alkyl, and wherein the sugar is an aldose selected from the group consisting of D-glucose, D-galactose, D-mannose, D-xylose, L-fucose, 2-acetamido-2-deoxy-D-glucose, 2-deoxy-2-phthalimido-glucose, 2-acetamido-2-deoxy-D-galactose, 2-azido-2-deoxy-D-glucose, 2-azido-2-deoxy-D-galactose, D-glucuronic acid and D-galacturonic acid, 2-deoxy-2-phthalimido glucose and 2-deoxy-2-phthalimido galactose.
Claim 2
Dependent Claim 112 words
An O-glycoside having the general formula: (sugar).sub.n --O--(CH.sub.2).sub.m --S--R--R' wherein n is an integer of from 1-10, inclusive, m is 2, R is selected from the group consisting of alkyl having 1-25 carbon atoms and aryl and R' is selected from the group consisting of H, CHO, CH(OR") 2 , NO 2 , NH 2 , OH, SH, COOH, COOCH 3 , COOCH 2 CH 3 , CONHNH 2 and CON 3 , wherein R" is C 1-4 -alkyl, and wherein the sugar is an aldose selected from the group consisting of D-glucose, D-galactose, D-mannose, D-xylose, L-fucose, 2-acetamido-2-deoxy-D-glucose, 2-deoxy-2-phthalimido-glucose, 2-acetamido-2-deoxy-D-galactose, 2-azido-2-deoxy-D-glucose, 2-azido-2-deoxy-D-galactose, D-glucuronic acid and D-galacturonic acid, 2-deoxy-2-phthalimido glucose and 2-deoxy-2-phthalimido galactose.

References Cited (Backward Citations)

US3547828A Cited
US4215213A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-06-22 1990-12-22 1991-06-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-06-22 1994-12-22 1995-06-23 $3760.00 Window Closed / Lapsed
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