US4988947A
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Amplitude and frequency/phase modulated pulses to achieve plane rotations of nuclear spin magnetization vectors with inhomogeneous B1
Assignee: University of Minnesota System
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Filing: 1989-09-13
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Granted: 1991-01-29
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Expires: 2009-09-13
Abstract
Abstract Two amplitude/frequency/phase modulated pulses that can achieve 90° plane rotations over large B 1 field inhomogeneities are described. The pulses achieve this by use of a "flip" in the direction of the effective B 1 field half-way through the pulse, and by use of a discontinuous phase jump in addition to continuous frequency of phase modulation. These pulse can be used for rotation of magnetization vectors between any plane that is perpendicular to the transverse plane and the transverse plane of the rotating reference frame. Consequently, then can be used for interchanging amplitude and phase information and converting amplitude modulated rotating frame experiments into phase modulated experiments.
Inventors
- 👤 Kamil Ugurbil
- 👤 Michael Garwood
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 11:25
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/446
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
154 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field, wherein with the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field Δω to create said effective field B 1 e desired as (B 1 2 +Δω 2 ) 1/2 , said pulse generated to cause a flip in the effective field B 1 e in said matter so that said magnetic spins undergo a plane rotation.
Claim 2
Independent Claim
154 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field, wherein with the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field Δω to create said effective field B 1 e desired as (B 1 2 +Δω 2 ) 1/2 , said pulse generated to cause a flip in the effective field B 1 e in said matter so that said magnetic spins undergo a plane rotation.
Claim 3
Independent Claim
159 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said adiabatic pulse generated to cause said B 1 e field to invert its direction, or flip, during the pulse so that said magnetic spins undergo a plane rotation.
Claim 4
Independent Claim
159 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said adiabatic pulse generated to cause said B 1 e field to invert its direction, or flip, during the pulse so that said magnetic spins undergo a plane rotation.
Claim 5
Dependent Claim
32 words
The method according to claim 1 or 2 wherein the amplitude and frequency of said pulse is modulated to control the range in said matter over which said plane rotation is achieved.
Claim 6
Dependent Claim
39 words
The method of claim 3 wherein said amplitude and frequency of said pulse are described by independent time dependent functions F 1 (η(t)) and F 2 (η(t)) respectively, wherein the time argument η(t) is a non-linear function of time.
Claim 7
Independent Claim
181 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; and (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field, wherein when the frequency of said pulse deviates from ω 0 , said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said pulse generated to include a substantially 180° phase shift in said B 1 field at a time when B 1 substantially equals said effective field B 1 e to flip said effective field B 1 e in said matter to cause said magnetic spins to undergo a plane rotation.
Claim 8
Independent Claim
181 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; and (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field, wherein when the frequency of said pulse deviates from ω 0 , said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said pulse generated to include a substantially 180° phase shift in said B 1 field at a time when B 1 substantially equals said effective field B 1 e to flip said effective field B 1 e in said matter to cause said magnetic spins to undergo a plane rotation.
Claim 9
Dependent Claim
31 words
A method according to claim 5 wherein said B 1 is shifted in phase and said effective field B 1 e is correspondingly flipped by changing the frequency of said pulse.
Claim 10
Dependent Claim
35 words
A method according to claim 5 wherein said B 1 is shifted in phase and said effective field B 1 e correspondingly is flipped by changing the time derivative of the phase of said pulse.
Claim 11
Dependent Claim
30 words
A method according to claim 5 wherein the amplitude and frequency of said pulse are modulated to control the range in said matter over which said plane rotation is achieved.
Claim 12
Dependent Claim
28 words
A method according to claim 5 wherein the frequency of said pulse is modulated to control the range in said matter over which said plane rotation is achieved.
Claim 13
Dependent Claim
40 words
A method of claim 8 wherein the amplitude and frequency of said pulse are described by independent time dependent functions F 1 (η(t)) and F 2 (η(t)) respectively, and further wherein the argument (η(t)) is a non-linear function of time.
Claim 14
Independent Claim
175 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by the said coil has components transverse to said B 0 field; (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined (B 1 2 +Δω 2 ) 1/2 , said adiabatic pulse generated to cause said Δω field to invert its direction at a time when B 1 e substantially equals Δω to cause said B 1 e field to flip during said pulse to cause said magnetic spins to undergo a plane rotation.
Claim 15
Independent Claim
175 words
A method for executing a plane rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by the said coil has components transverse to said B 0 field; (c) energizing said coil to generate an RF adiabatic pulse providing said B 1 field wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined (B 1 2 +Δω 2 ) 1/2 , said adiabatic pulse generated to cause said Δω field to invert its direction at a time when B 1 e substantially equals Δω to cause said B 1 e field to flip during said pulse to cause said magnetic spins to undergo a plane rotation.
Claim 16
Dependent Claim
24 words
A method according to claim 11 wherein said Δω and effective field B 1 e is inverted by changing the frequency of said pulse.
Claim 17
Dependent Claim
31 words
A method according to claim 11 wherein said Δω and effective field B 1 e is inverted by changing the sign of the time derivative of the plane of said pulse.
Claim 18
Dependent Claim
30 words
A method according to claim 11 wherein the amplitude and frequency of said pulse are modulated to control the range in said matter over which said plane rotation is achieved.
Claim 19
Dependent Claim
28 words
A method according to claim 11 wherein the frequency of said pulse is modulated to control the range in said matter over which said plane rotation is achieved.
Claim 20
Dependent Claim
40 words
A method of claim 14 wherein the amplitude and frequency of said pulse are described by independent time dependent functions F 1 (η(t)) and F 2 (η(t)) respectively, and further wherein the argument (η(t)) is a non-linear function of time.
Claim 21
Independent Claim
311 words
A method for executing a plate rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to provide an RF adiabatic pulse providing said B 1 field, wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said pulse generated to have at least two contiguous segments described by the equations: ##EQU7## ##EQU8## wherein: F 1 and F 2 (t) are functions of time; Δω is defined as (|ω 0 |-|ω(t)|) with ω 0 designating the Larmor frequency of said set of magnetic spins and ω(t) designating the frequency of said adiabatic pulse; v is a parameter which takes into account variations in B 1 magnitude through space and is the ratio of peak B 1 amplitude to the peak frequency modulation amplitude A so that if B 1 changes in space so does v; A is a parameter designating the maximum amplitude of the B 1 field; Δω(t) for segment 2 is a negative relative to Δω(t) for segment 1 at time t 1 to provide for a flip in the B 1 e direction at the time t 1 ; B 1 e =B 1 at the beginning and end of said pulse and B 1 e =Δω when said flip in the B 1 e field is accomplished; and so that said pulse is generated to cause said magnetic spins to undergo a plane rotation.
Claim 22
Independent Claim
311 words
A method for executing a plate rotation of magnetic spins in matter under the influence of a spin aligning magnetic field B 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to provide an RF adiabatic pulse providing said B 1 field, wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said pulse generated to have at least two contiguous segments described by the equations: ##EQU7## ##EQU8## wherein: F 1 and F 2 (t) are functions of time; Δω is defined as (|ω 0 |-|ω(t)|) with ω 0 designating the Larmor frequency of said set of magnetic spins and ω(t) designating the frequency of said adiabatic pulse; v is a parameter which takes into account variations in B 1 magnitude through space and is the ratio of peak B 1 amplitude to the peak frequency modulation amplitude A so that if B 1 changes in space so does v; A is a parameter designating the maximum amplitude of the B 1 field; Δω(t) for segment 2 is a negative relative to Δω(t) for segment 1 at time t 1 to provide for a flip in the B 1 e direction at the time t 1 ; B 1 e =B 1 at the beginning and end of said pulse and B 1 e =Δω when said flip in the B 1 e field is accomplished; and so that said pulse is generated to cause said magnetic spins to undergo a plane rotation.
Claim 23
Independent Claim
321 words
A method for executing a plane rotation of magnetic spins in matter under the influence of spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to provide an RF adiabatic pulse providing said B 1 field, wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said pulse having at least two contiguous segments described by the equations: ##EQU9## ##EQU10## wherein: F 1 (t) and F 2 (t) are functions of time; Δω is defined as (|ω 0 |-|ω(t)|) with ω 0 designating the Larmor frequency of said set of magnetic spins and ω(t) designating the frequency of said adiabatic pulse; v is a parameter which takes into account variations in B 1 magnitude through space and is the ratio of peak B 1 amplitude to the peak frequency modulation amplitude A so that if B 1 changes in space so does v; A is a parameter designating the maximum amplitude of the B 1 field; B 1 e =B 1 at time t 1 ; B 1 (t) for segment 2 is negative or in other words 180° out of phase relative to B 1 (t) for segment 1 at time t 1 to provide a flip in the B 1 e direction at time t 1 ; B 1 e =Δω at the beginning and end of said pulse; and so that said pulse is generated to cause said magnetic spins to undergo a plane rotation.
Claim 24
Independent Claim
321 words
A method for executing a plane rotation of magnetic spins in matter under the influence of spin aligning magnetic field B 0 , said magnetic spins having a Larmor frequency ω 0 , said method comprising the steps of: (a) providing a coil responsive to electrical energization to generate a B 1 field; (b) orienting said coil so that the B 1 field generated by said coil has components transverse to said B 0 field; (c) energizing said coil to provide an RF adiabatic pulse providing said B 1 field, wherein when the frequency of said pulse deviates from ω 0 said spins encounter an additional magnetic field of magnitude Δω to create an effective field B 1 e defined as (B 1 2 +Δω 2 ) 1/2 , said pulse having at least two contiguous segments described by the equations: ##EQU9## ##EQU10## wherein: F 1 (t) and F 2 (t) are functions of time; Δω is defined as (|ω 0 |-|ω(t)|) with ω 0 designating the Larmor frequency of said set of magnetic spins and ω(t) designating the frequency of said adiabatic pulse; v is a parameter which takes into account variations in B 1 magnitude through space and is the ratio of peak B 1 amplitude to the peak frequency modulation amplitude A so that if B 1 changes in space so does v; A is a parameter designating the maximum amplitude of the B 1 field; B 1 e =B 1 at time t 1 ; B 1 (t) for segment 2 is negative or in other words 180° out of phase relative to B 1 (t) for segment 1 at time t 1 to provide a flip in the B 1 e direction at time t 1 ; B 1 e =Δω at the beginning and end of said pulse; and so that said pulse is generated to cause said magnetic spins to undergo a plane rotation.
Claim 25
Dependent Claim
110 words
A method according to claim 1 wherein said adiabatic pulse induces a well-defined rotation about a well-defined axis in a first rotating frame of reference, said first rotating frame of reference rotating at the instantaneous frequency of said pulse, and further wherein for all B 1 magnitudes through said matter the net β is zero at the end of said pulse, wherein β is the angle through which magnetization vectors in said matter rotate about B 1 e in a second rotating frame of reference rotating with B 1 e such that the axis along which B 1 e is aligned is stationary in said second rotating frame of reference.
Claim 26
Dependent Claim
110 words
A method according to claim 2 wherein said adiabatic pulse induces a well-defined rotation about a well-defined axis in a first rotating frame of reference, said first rotating frame of reference rotating at the instantaneous frequency of said pulse, and further wherein for all B 1 magnitudes through said matter the net β is zero at the end of said pulse, wherein β is the angle through which magnetization vectors in said matter rotate about B 1 e in a second rotating frame of reference rotating with B 1 e such that the axis along which B 1 e is aligned is stationary in said second rotating frame of reference.
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