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US4868501A Expired / Lapsed US ⏱️ 0.0 years remaining

Method and means for magnetic resonance spin-echo imaging using an adiabatic three pi pulse sequence

Assignee: Leland Stanford Junior University
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Filing: 1988-06-10
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Granted: 1989-09-19
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Expires: 2008-06-10
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Abstract

Abstract An adiabatic pulse suitable for generating selective spin echoes for both MR imaging and spectroscopy is described. The pulse requires no gradient reversal to achieve phase compensation. Like adiabatic inversion pulses the new pulse performs a pi rotation for any amplitude exceeding a threshold. Unlike inversion pulses, this pulse leaves no phase variation across the slice. The pulse is actually a composite consisting of a 2 pi and a pi pulse. The 2 pi pulse merely compensates for the phase of the pi phase; it performs no net rotation. This compensation is immune to RF inhomogeneity and nonlinearity.

Inventors

  • 👤 Steven M. Conolly

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 12:35
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/446

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 73 words
In spin-echo magnetic resonance imaging and spectroscopy, a method of refocusing dephased nuclei spins in an inhomogeneous RF magnetic field comprising the steps of applying a first selective adiabatic pulse for rotating nuclei spins 360 degrees (2π), and applying a second selective adiabatic pulse for rotating nuclei spins 180 degrees (π) for creating a spin echo, said first pulse producing no net nuclei rotation and compensating for phase variations of said second pulse.
Claim 2
Dependent Claim 73 words
In spin-echo magnetic resonance imaging and spectroscopy, a method of refocusing dephased nuclei spins in an inhomogeneous RF magnetic field comprising the steps of applying a first selective adiabatic pulse for rotating nuclei spins 360 degrees (2π), and applying a second selective adiabatic pulse for rotating nuclei spins 180 degrees (π) for creating a spin echo, said first pulse producing no net nuclei rotation and compensating for phase variations of said second pulse.
Claim 3
Dependent Claim 15 words
The method as defined by claim 1 wherein said first pulse precedes said second pulse.
Claim 4
Dependent Claim 15 words
The method as defined by claim 1 wherein said second pulse precedes said first pulse
Claim 5
Dependent Claim 23 words
The method as defined by claim 1 wherein the duration of said second pulse is equal to the duration of said first pulse.
Claim 6
Dependent Claim 60 words
The method as defined by claim 4 wherein said first and second pulses are hyperbolic secants, B 1 (t) i0 (t) and defined by the following table: ______________________________________ Duration B.sub.1 (t) φ (t) ______________________________________ 2π T/4 μβ sech (βt) -μ ln sech (βt) T/4 -μβ sech (βt) μ ln sech (βt) π T/2 -μβ sech(βt/2) 2μ ln sech (βt/2) ______________________________________
Claim 7
Dependent Claim 70 words
The method as defined by claim 5 wherein the sampling schedule of said first and second pulses is given by the following table: ______________________________________ Pulse Interval i t [i] ______________________________________ 2π 0 ≦ i < n t.sub.0 + i/n n ≦ i < 2n t.sub.0 + (i - n)/n π 2n ≦ i < 4n t.sub.1 + (i - 2n)/n ______________________________________ where t o =-1/2+1/(2n) and t 1 =-1 +1/(2n).
Claim 8
Independent Claim 119 words
A method of spin-echo imaging using magnet resonance techniques comprising the steps of (a) positioning an object to be imaged in a static magnet field with a gradient magnet field superimposed thereon, the composite field being inhomogeneous, (b) applying a 90-degree RF pulse to said object at the Larmor frequency for a selected slice to be imaged, (c) thereafter applying a 3π adiabatic pulse to refocus dephased nuclei spins in said selected slice, said 3π adiabatic pulse including a 2π pulse and a π pulse where said 2π pulse produces no net nuclei rotation and compensates for phase variations introduced by said π pulse, and (d) detecting a spin echo of the refocused nuclei spins in said selected slice.
Claim 9
Independent Claim 119 words
A method of spin-echo imaging using magnet resonance techniques comprising the steps of (a) positioning an object to be imaged in a static magnet field with a gradient magnet field superimposed thereon, the composite field being inhomogeneous, (b) applying a 90-degree RF pulse to said object at the Larmor frequency for a selected slice to be imaged, (c) thereafter applying a 3π adiabatic pulse to refocus dephased nuclei spins in said selected slice, said 3π adiabatic pulse including a 2π pulse and a π pulse where said 2π pulse produces no net nuclei rotation and compensates for phase variations introduced by said π pulse, and (d) detecting a spin echo of the refocused nuclei spins in said selected slice.
Claim 10
Dependent Claim 23 words
The method as defined by claim 7 where the duration of said π pulse is equal to the duration of said 2π pulse.
Claim 11
Dependent Claim 59 words
The method as defined by claim 8 wherein said first and second pulses are hyperbolic secants, B 1 (t) i φ(t) and defined by the following table: ______________________________________ Duration B.sub.1 (t) φ(t) ______________________________________ 2π T/4 μβ sech (βt) -μ ln sech(βt) T/4 -μβ sech (βt) μ ln sech (βt) π T/2 -μβ sech (βt/2) 2μ ln sech (βt/2) ______________________________________
Claim 12
Dependent Claim 71 words
The method as defined by claim 9 wherein the sampling schedule of said first and second pulses is given by the following table: ______________________________________ Pulse Interval i t [i] ______________________________________ 2π 0 ≦ i < n t.sub.0 + i/n n ≦ i < 2n t.sub.0 + (i - n)/n π 2n ≦ i < 4n t.sub.1 + (i - 2n)/n ______________________________________ where t o =-1/2+1 (2n) and t 1 =-1 +1(2N).
Claim 13
Dependent Claim 121 words
Apparatus for magnetic resonant imaging a slice through an object using spin-echo techniques, comprising (a) means for establishing a static magnetic field said object, (b) means for superimposing a gradient magnetic field said static magnetic field, (c) means for applying a 90-degree RF pulse to said object at the Larmor frequency for a selected slice to be imaged, (d) means for applying a 3π adiabatic pulse to refocus dephased nuclei spins in selected slice, said 3π adiabatic pulse including a 2π pulse and a π pulse where said 2π pulse produces no net nuclei rotation and compensates for phase variations introduced by said π pulse, and (d) means for detecting a spin echo of the refocused spins in said selected slice.
Claim 14
Dependent Claim 121 words
Apparatus for magnetic resonant imaging a slice through an object using spin-echo techniques, comprising (a) means for establishing a static magnetic field said object, (b) means for superimposing a gradient magnetic field said static magnetic field, (c) means for applying a 90-degree RF pulse to said object at the Larmor frequency for a selected slice to be imaged, (d) means for applying a 3π adiabatic pulse to refocus dephased nuclei spins in selected slice, said 3π adiabatic pulse including a 2π pulse and a π pulse where said 2π pulse produces no net nuclei rotation and compensates for phase variations introduced by said π pulse, and (d) means for detecting a spin echo of the refocused spins in said selected slice.
Claim 15
Dependent Claim 22 words
Apparatus as defined by claim 11 wherein the duration of said π pulse is equal to the duration of said 2π pulse.
Claim 16
Dependent Claim 60 words
Apparatus as defined by claim 12 wherein said first and second pulses are hyperbolic secants, B 1 (t) i φ(t) and defined by the following table: ______________________________________ Duration B.sub.1 (t) φ (t) ______________________________________ 2π T/4 μβ sech (βt) -μ ln sech (βt) T/4 -μβ sech (βt) μ ln sech (βt) π T/2 -μβ sech (βt/2) 2μ ln sech (βt/2) ______________________________________
Claim 17
Dependent Claim 68 words
Apparatus as defined by claim 10 wherein the sampling schedule of said first and second pulses is given by the following table: ______________________________________ Pulse Interval i t [i] ______________________________________ 2π 0 ≦ i < n t.sub.0 + i/n n ≦ i < 2n t.sub.0 + (i - n)/n π 2n ≦ i < 4n t.sub.1 + (i - 2n)/n ______________________________________ where t 0 =-1/2+1/(2n) and t 1 =-1+1/(2n).

References Cited (Backward Citations)

US4442404A Cited
US4528509A Cited
US4486709A Cited
US4581581A Cited
US4727324A Cited
US4661775A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-09-18 1993-03-20 1993-09-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-09-18 1997-03-20 1997-09-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-09-18 2001-03-20 2001-09-19 $7700.00 Window Closed / Lapsed

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