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US4985252A
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Medication, dietetic product and hygienic product in the form of a powered composition obtained by adsorption of active ingredients on a rapidly dissolving sugar and process for obtaining said composition
Assignee: RIPH RECHERCHE INFORMATIQUE ET PHARMACIE (SARL)
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Filing: 1988-04-04
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Granted: 1991-01-15
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Expires: 2008-04-04
Abstract
Abstract A powdered composition obtained by adsorption of active ingedients, previously dissolved in an organic solvent, on instant sugar, and a process for producing this composition. As a medication, it contains at least one medically active ingredient adsorbed on the external and/or internal surface of particles of an instant sugar very rapidly soluble in water.
Inventors
- 👤 Christophe Jung
- 👤 Jean Jung
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 00:53
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1617; A61K9/1623; A61K9/141; A61K9/145
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
68 words
A powdered composition, characterized in that it consists essentially of at least one medically active ingredient adsorbed on the external and/or internal surface of particles of instant sugar selected from the group consisting of sucrose, glucose and lactose, produced by evaporating an organic solvent solution of said active ingredient containing said instant sugar dispersed therein, said organic solvent solution comprising an organic solvent not dissolving said instant sugar.
Claim 2
Dependent Claim
68 words
A powdered composition, characterized in that it consists essentially of at least one medically active ingredient adsorbed on the external and/or internal surface of particles of instant sugar selected from the group consisting of sucrose, glucose and lactose, produced by evaporating an organic solvent solution of said active ingredient containing said instant sugar dispersed therein, said organic solvent solution comprising an organic solvent not dissolving said instant sugar.
Claim 3
Dependent Claim
24 words
Composition according to claim 1, wherein said at least one medically active ingredient is a compound insoluble in water, but soluble in organic solvents.
Claim 4
Dependent Claim
29 words
Composition according to claim 1, which contains at least one active ingredient free from an amino group, said at least one compound being insoluble in saliva or acid medium.
Claim 5
Dependent Claim
39 words
Composition according to claim 1 in which said at least one active ingredient is in amorphous or microcrystalline form or in the form of liquid globules, uniformly distributed at the surface and/or the interior of particles of instant sugar.
Claim 6
Dependent Claim
13 words
Composition according to claim 1 in the form of a dry solid galenic.
Claim 7
Dependent Claim
54 words
Process for the production of a powdered composition consisting essentially of dissolving at least one medically active ingredient in an organic solvent, mixing the organic solvent solution obtained with instant sugar selected from the group consisting of sucrose, glucose and lactose, said organic solvent not dissolving said instant sugar, then evaporating the organic solvent.
Claim 8
Dependent Claim
54 words
Process for the production of a powdered composition consisting essentially of dissolving at least one medically active ingredient in an organic solvent, mixing the organic solvent solution obtained with instant sugar selected from the group consisting of sucrose, glucose and lactose, said organic solvent not dissolving said instant sugar, then evaporating the organic solvent.
Claim 9
Dependent Claim
35 words
Process according to claim 6, which comprises reacting an ether solution of vitamin E, as liquid active ingredient, with instant sugar, then evaporating the solvent until it is completely eliminated and obtaining a pulverulent mass.
Claim 10
Dependent Claim
22 words
Process according to claim 6, in which at least one essential oil used in aroma therapy are admixed with the instant sugar.
Claim 11
Dependent Claim
24 words
Process according to claim 6, in which a methylene chloride solution of indomethacin is admixed with the instant sugar, and evaporating the organic solvent.
Claim 12
Dependent Claim
38 words
Process according to claim 6, in which as organic solvent there is used a member selected from the group consisting of an ether, and ester, a ketone, an acid, an alcohol, a halogenated solvent, and a hydrocarbon solvent.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-01-14 | 1994-07-16 | 1995-01-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-01-14 | 1998-07-16 | 1999-01-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-01-14 | 2002-07-16 | 2003-01-15 | $7700.00 | Window Closed / Lapsed |