US4985236A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tripolyphosphate-containing anti-calculus toothpaste
Assignee: GlaxoSmithKline LLC
•
Filing: 1989-09-14
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Granted: 1991-01-15
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Expires: 2009-09-14
Abstract
Abstract A storage stable anticalculus toothpaste comprising at least about 4%, by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, a silica or plastics dental abrasive and an orally acceptable vehicle, the toothpaste having a pH of from about 8 to about 10.
Inventors
- 👤 Nader Ibrahim
- 👤 Jeanette L. Sodano
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 09:25
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/24; A61K2800/00; A61K2800/74; A61K2800/78; A61K2800/782
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
74 words
A toothpaste, which comprises at least about 4% by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, a silica or plastics dental abrasive and an orally acceptable vehicle, the toothpaste having a pH of from about 8 to about 10.
Claim 2
Dependent Claim
74 words
A toothpaste, which comprises at least about 4% by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, a silica or plastics dental abrasive and an orally acceptable vehicle, the toothpaste having a pH of from about 8 to about 10.
Claim 3
Dependent Claim
15 words
The toothpaste according to claim 1, wherein said water-soluble alkali metal tripolyphosphate is sodium tripolyphosphate.
Claim 4
Dependent Claim
33 words
The toothpaste according to claim 1, wherein said water-soluble alkali metal tripolyphosphate is present in an amount of from about 4 to 6%, by weight, based on the total weight of the toothpaste.
Claim 5
Dependent Claim
16 words
The toothpaste according to claim 1, wherein said pH is from about 8 to about 9.
Claim 6
Dependent Claim
16 words
The toothpaste according to claim 1, wherein said fluoride ion source is an alkali metal fluoride.
Claim 7
Dependent Claim
14 words
The toothpaste according to claim 5, wherein said alkali metal fluoride is sodium fluoride.
Claim 8
Dependent Claim
17 words
The toothpaste according to claim 1, wherein said orally acceptable vehicle is an aqueous orally acceptable vehicle.
Claim 9
Dependent Claim
15 words
The toothpaste according to claim 7, wherein said aqueous orally acceptable vehicle comprises a humectant.
Claim 10
Dependent Claim
94 words
A toothpaste, which comprises at least about 4%, by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, from about 5 to about 30% by weight, based on the total weight of the toothpaste, of a silica dental abrasive and an orally acceptable vehicle comprising a binder or thickener, the toothpaste having a pH of from about 8 to about 10.
Claim 11
Dependent Claim
94 words
A toothpaste, which comprises at least about 4%, by weight, based on the total weight of the toothpaste, of a water-soluble alkali metal tripolyphosphate, a phosphatase enzyme inhibitor consisting of a fluoride ion source in an amount sufficient to supply from about 25 ppm to about 3500 ppm of fluoride ion, from about 5 to about 30% by weight, based on the total weight of the toothpaste, of a silica dental abrasive and an orally acceptable vehicle comprising a binder or thickener, the toothpaste having a pH of from about 8 to about 10.
Claim 12
Dependent Claim
15 words
The toothpaste according to claim 9, wherein said water-soluble alkali metal tripolyphosphate is sodium tripolyphosphate.
Claim 13
Dependent Claim
34 words
The toothpaste according to claim 9, wherein said water-soluble alkali metal tripolyphosphate is present in an amount of from about 4 to about 6%, by weight, based on the total weight of the toothpaste.
Claim 14
Dependent Claim
16 words
The toothpaste according to claim 9, wherein said pH is from about 8 to about 9.
Claim 15
Dependent Claim
16 words
The toothpaste according to claim 9, wherein said fluoride ion source is an alkali metal fluoride.
Claim 16
Dependent Claim
14 words
The toothpaste according to claim 13, wherein said alkali metal fluoride is sodium fluoride.
Claim 17
Dependent Claim
17 words
The toothpaste according to claim 9, wherein said orally acceptable vehicle is an aqueous orally acceptable vehicle.
Claim 18
Dependent Claim
15 words
The toothpaste according to claim 15, wherein said aqueous orally acceptable vehicle comprises a humectant.
Claim 19
Dependent Claim
37 words
A method of treating humans who are susceptible to the formation of dental calculus, which comprises applying to the teeth of such calculus formers a toothpaste according to claim 1, thereby to inhibit formation of dental calculus.
Claim 20
Dependent Claim
37 words
A method of treating humans who are susceptible to the formation of dental calculus, which comprises applying to the teeth of such calculus formers a toothpaste according to claim 9, thereby to inhibit formation of dental calculus.
Claim 21
Dependent Claim
59 words
A method of preparing the toothpaste according to claim 1, which comprises admixing said water-soluble tripolyphosphate in the form of a powder with said phosphatase inhibitor, said dental abrasive and said orally acceptable vehicle, and adding an amount of a base suitable for use in the oral cavity to provide a pH of from about 8 to about 10.
Claim 22
Dependent Claim
60 words
A method of preparing the toothpaste according to claim 9, which comprises admixing said water-soluble tripolyphosphate in the form of a powder with said phosphatase inhibitor, said silica dental abrasive and said orally acceptable vehicle, and adding an amount of a base suitable for use in the oral cavity to provide a pH of from about 8 to about 10.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1994-01-14 | 1994-07-16 | 1995-01-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1998-01-14 | 1998-07-16 | 1999-01-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2002-01-14 | 2002-07-16 | 2003-01-15 | $7700.00 | Window Closed / Lapsed |