US4340583A
Expired / Lapsed
US
⏱️ 0.0 years remaining
High fluoride compatibility dentifrice abrasives and compositions
Assignee: JM Huber Corp
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Filing: 1980-09-23
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Granted: 1982-07-20
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Expires: 2000-09-23
Abstract
Abstract Novel precipitated silicon dioxide abrasive compositions which can be incorporated into therapeutic toothpaste compositions containing both soluble fluoride salts and soluble phosphate salts are disclosed. The abrasive comprise low structure precipitated silicon dioxides which have been reacted with about 10 to 300 parts per million alkaline earth metal ion, particularly calcium. Reaction with the alkaline earth metal ion minimizes abrasive interaction with the fluoride ion source in therapeutic toothpaste. Also provided are methods for preparation of the novel silicon dioxide abrasives and resulting toothpaste formulations containing such abrasives.
Inventors
- 👤 Satish K. Wason
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 06:20
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/25; A61Q; A61Q11/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
210 words
A toothpaste composition, comprising: A. from about 6% to 35% by weight of a precipitated silica abrasive material which is a precipitated amorphous silicon dioxide prepared from fresh water alkali silicate by acidulation, which has been intimately reacted with a solution of a salt of an alkaline earth metal so as to have present about 10-300 parts per million of alkaline earth metal ions in said amorphous silicon dioxide, said amorphous silicon dioxide exhibiting a Radio-active Dentin Abrasion value of at least 40, an average particle size of from about 5 to 15 microns in diameter, a pack density of about 0.24 to 0.55 grams per milliliter, an oil absorption of about 70-95 ccs/100 grams, a BET surface area of about 100-250 m 2 /g, and a percent loss on ignition of about 4-6%; B. from about 0.01% to 3.0% by weight of a water-soluble, fluorine containing material which yields fluoride ions in aqueous solution; C. from about 3% to 55% by weight of a humectant; D. from about 0.2% to 2.0% by weight of a binding agent; and E. from about 15% to 80% by weight of water; said composition providing a pH of from about 4 to 8 when slurried with water in a 3:1 water/composition weight ratio.
Claim 2
Dependent Claim
210 words
A toothpaste composition, comprising: A. from about 6% to 35% by weight of a precipitated silica abrasive material which is a precipitated amorphous silicon dioxide prepared from fresh water alkali silicate by acidulation, which has been intimately reacted with a solution of a salt of an alkaline earth metal so as to have present about 10-300 parts per million of alkaline earth metal ions in said amorphous silicon dioxide, said amorphous silicon dioxide exhibiting a Radio-active Dentin Abrasion value of at least 40, an average particle size of from about 5 to 15 microns in diameter, a pack density of about 0.24 to 0.55 grams per milliliter, an oil absorption of about 70-95 ccs/100 grams, a BET surface area of about 100-250 m 2 /g, and a percent loss on ignition of about 4-6%; B. from about 0.01% to 3.0% by weight of a water-soluble, fluorine containing material which yields fluoride ions in aqueous solution; C. from about 3% to 55% by weight of a humectant; D. from about 0.2% to 2.0% by weight of a binding agent; and E. from about 15% to 80% by weight of water; said composition providing a pH of from about 4 to 8 when slurried with water in a 3:1 water/composition weight ratio.
Claim 3
Dependent Claim
42 words
A toothpaste composition in accordance with claim 1, which composition additionally contains from about 5% to 12% by weight of a water-soluble phosphate pellicle film penetration agent selected from the group consisting of orthophosphate salts, pyrophosphate salts, tripolyphosphate salts and metaphosphate salts.
Claim 4
Dependent Claim
80 words
A toothpaste composition in accordance with claim 2 wherein: A. the precipitated silica abrasive comprises from about 10% to 20% by weight of the composition; B. the fluorine-containing material comprises from about 0.1% to 1.0% by weight of the composition; C. the humectant comprises from about 20% to 35% by weight of the composition; D. the water component comprises from about 15% to 40%; and E. the pH provided by a 3:1 water/composition slurry ranges from about 6.5 to 7.5.
Claim 5
Dependent Claim
71 words
A composition in accordance with claim 3 which composition additionally contains from about 0.1% to 6% by weight of the composition of a sudsing agent; and wherein A. the fluorine-containing material is selected from the group consisting of sodium fluoride and stannous fluoride; B. the phosphate pellicle film penetration agent is an orthophosphate salt; and C. the humectant is selected from the group consisting of glycerine, sorbitol, xylitol and mixtures thereof.
Claim 6
Dependent Claim
73 words
A composition in accordance with claim 4 wherein A. the fluorine-containing material is sodium fluoride; and B. the sudsing agent is selected from the grop consisting of: 1. the water-soluble salts of alkyl sulfates having from about 8 to 18 carbon atoms in the alkyl radical, 2. the water-soluble salts of sulfonated monoglycerides of fatty acids having from about 8 to 18 carbon atoms in the fatty acid moiety; and 3. mixtures thereof.
Claim 7
Dependent Claim
13 words
A composition in accordance with claim 3 wherein the binding agent is carrageenan.
Claim 8
Dependent Claim
85 words
A composition in accordance with claim 4 which composition additionally contains from about 0.2% to 5% by weight of the toothpaste composition of a second pellicle film penetration agent selected from the group consisting of citric acid, trisodium citrate, malic acid and tartaric acid; and wherein A. the fluorine-containing material is sodium fluoride; and B. the phosphate pellicle film penetration agent is a mixture of sodium dihydrogen phosphate monohydrate and disodium hydrogen phosphate dihydrate in monosodium to disodium weight ratio of about 1:3 to 1:5.
Claim 9
Dependent Claim
82 words
A toothpaste composition in accordance with claim 3 which contains an additional component selected from the group consisting of A. from about 0.01% to 2% by weight of a flavoring agent; B. from about 0.05% to 3% by weight of a sweetening agent; C. from about 0.01% to 2.5% by weight of an anticalculus agent which is disodium ethane-1 hydroxy-1,10diphosphonate; D. from about 0.01% to 2.5% by weight of a bisbiguanide antiplaque agent; and E. mixtures of these additional toothpaste composition components.
References Cited (Backward Citations)
DE547129C
Cited
US2399237A
Cited
US2649388A
Cited
US2744001A
Cited
US2820000A
Cited
DE1054434B
Cited
US3122483A
Cited
NO116438B
Cited
US3227618A
Cited
AU405934B2
Cited
NO124095B
Cited
US3864471A
Cited
US3624199A
Cited
NO131018C
Cited
US3911104A
Cited
AT320158B
Cited
AT327391B
Cited
AT327392B
Cited
US3864470A
Cited
US3928541A
Cited
US3893840A
Cited
US3988162A
Cited
AU7257874A
Cited
US3977893A
Cited
US3991177A
Cited
FR2258168A1
Cited
US4067746A
Cited
US4144321A
Cited
US4015996A
Cited
US4024239A
Cited
US4062658A
Cited
US4159280A
Cited
US4244707A
Cited
US4280822A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1985-07-19 | 1986-01-18 | 1986-07-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1989-07-19 | 1990-01-18 | 1990-07-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1993-07-19 | 1994-01-18 | 1994-07-20 | $7700.00 | Window Closed / Lapsed |