Patent US4980150A successfully refreshed from Google Patents.
US4980150A
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US
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Chlorhexidine complex
Assignee: Zetachron Inc
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Filing: 1989-04-27
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Granted: 1990-12-25
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Expires: 2009-04-27
Abstract
Abstract A chlorhexidine complex is prepared by complexing chlorhexidine (a divalent, cationic antiseptic) with an anionic polymer such as algin or carboxymethylcellulose. The complex is insoluble but can be granulated or crushed to a fine powder. In powdered form the complex forms stable aqueous dispersions. The chlorhexidine complex is suitable for inclusion in oral hygiene compositions such as dentrifrices, and in other antibacterial compositions such as opthalmic under-eye-lid treatment capsules topical preparations and ocular solutions.
Inventors
- 👤 Alec D. Keith
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 13:55
CPC Classifications
C; C08; C08B; C08B37/00; C08B37/006; C08B37/0084; A; A01; A01N; A01N47/00; A01N47/40; A01N47/42; A01N47/44; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/43; A61K8/72; A61K8/73; A61K8/731; A61K8/733; A61Q; A61Q11/00; C08B11/00; C08B11/20; A61K2800/00; A61K2800/40; A61K2800/54; A61K2800/542; A61K2800/5424
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
61 words
An antibacterial composition, comprising: an amount of an ionic complex, of chlorhexidine and an anionic polymer, effective to inhibit microorganism viability upon application of said complex to human tissue selected from the group consisting of dermis and mucosa, a pharmaceutically acceptable excipient therefore, and the antibacterial composition being characterized by its ability to contact human oral mucosa without eventuating bitter taste.
Claim 2
Dependent Claim
61 words
An antibacterial composition, comprising: an amount of an ionic complex, of chlorhexidine and an anionic polymer, effective to inhibit microorganism viability upon application of said complex to human tissue selected from the group consisting of dermis and mucosa, a pharmaceutically acceptable excipient therefore, and the antibacterial composition being characterized by its ability to contact human oral mucosa without eventuating bitter taste.
Claim 3
Dependent Claim
29 words
The antibacterial composition according to claim 1 wherein said anionic polymer is selected from the group consisting of algin, anionic cellulose polymers, anionic acetate polymers and anionic acrylic polymers.
Claim 4
Dependent Claim
23 words
The antibacterial composition according to claim 1 wherein said anionic polymer is selected from the group consisting of algin, carboxymethylcellulose, hydroxypropylmethylcellulose and hydroxypropylcellulose.
Claim 5
Dependent Claim
18 words
The antibacterial composition according to claim 3 wherein said ionic complex is insoluble and is in powdered form.
Claim 6
Dependent Claim
39 words
The antibacterial composition according to claim 3 wherein said ionic complex is further characterized by its ability to contact human oral mucosa without staining human enamel at all or to a lesser degree than free chlorhexidine stains human enamel.
Claim 7
Dependent Claim
25 words
The antibacterial composition according to claim 5 wherein said pharmaceutically acceptable excipient further comprises a dentifrice composition, within which said ionic complex is stably dispersed.
Claim 8
Dependent Claim
27 words
The antibacterial composition according to claim 5 wherein said pharmaceutically acceptable excipient further comprises an aqueous mouth rinse composition, within which said ionic complex is stably dispersed.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-12-24 | 1994-06-25 | 1994-12-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-12-24 | 1998-06-25 | 1998-12-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-12-24 | 2002-06-25 | 2002-12-25 | $7700.00 | Window Closed / Lapsed |