US4569837A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical preparation for remedy of periodontal disease and process for production thereof
Assignee: Teijin Ltd
•
Filing: 1984-06-01
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Granted: 1986-02-11
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Expires: 2004-06-01
Abstract
Abstract A pharmaceutical preparation for remedy of periodontal diseases, which is in the form of a film or sheet and is inserted in a periodontal pocket or gingiva, said pharmaceutical preparation comprising a water-soluble polymeric substance having a Young's modulus of 10 to 250 Kg/mm 2 as determined at a temperature of 25° C. and a relative humidity of 65%, and a viscosity of the 2% aqueous solution of 5 to 30,000 CP as determined at 20° C. and a medicinal agent for remedy of periodontal diseases. This pharmaceutical preparation can be prepared by dissolving the above-mentioned water-soluble polymeric substance and medicinal agent in an organic solvent, casting the resultant solution, and removing the organic solvent by drying to obtain a pharmaceutical preparation in the form of a film or sheet.
Inventors
- 👤 Yoshiki Suzuki
- 👤 Hiroshi Ikura
- 👤 Toshihide Noguchi
- 👤 Katsunori Izumizawa
- 👤 Shiro Kinoshita, deceased
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0063; A61P; A61P1/00; A61P1/02
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
86 words
A method of remedying periodontal diseases comprising inserting a pharmaceutical preparation in the form of a film or sheet into a periodontal pocket or gingival region, wherein said pharmaceutical preparation consists essentially of a water-soluble polymeric substance having a Young's modulus of 10 to 250 Kg/mm 2 as determined at a temperature of 25° C. and a relative humidity of 65%, and a viscosity of a 2% aqueous solution of 5 to 30,000 CP as determined at 20° C. and a medicinal agent for periodontal disease.
Claim 2
Independent Claim
86 words
A method of remedying periodontal diseases comprising inserting a pharmaceutical preparation in the form of a film or sheet into a periodontal pocket or gingival region, wherein said pharmaceutical preparation consists essentially of a water-soluble polymeric substance having a Young's modulus of 10 to 250 Kg/mm 2 as determined at a temperature of 25° C. and a relative humidity of 65%, and a viscosity of a 2% aqueous solution of 5 to 30,000 CP as determined at 20° C. and a medicinal agent for periodontal disease.
Claim 3
Dependent Claim
40 words
The method of remedying periodontal diseases as claimed in claim 1, wherein the Young's modulus of the water-soluble polymeric substance is 15 to 200 Kg/mm 2 as determined at a temperature of 25° C. and a relative humidity of 65%.
Claim 4
Dependent Claim
34 words
The method of remedying periodontal diseases as claimed in claim 1, wherein the viscosity of a 2% aqueous solution of the water-soluble polymeric substance is 10 to 27,000 CP as determined at 20° C.
Claim 5
Dependent Claim
30 words
The method of remedying periodontal diseases as claimed in claim 1, wherein the water-soluble polymeric substance is a polysaccharide, a derivative thereof, a water-soluble vinyl polymer or a mixture thereof.
Claim 6
Dependent Claim
24 words
The method of remedying periodontal diseases as claimed in claim 4, wherein the polysaccharide or derivative thereof is a lower alkyl ether of cellulose.
Claim 7
Dependent Claim
39 words
The method of remedying periodontal diseases as claimed in claim 5, wherein the lower alkyl ether of cellulose is methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, sodium carboxymethyl cellulose or a mixture of two or more of said cellulose derivatives.
Claim 8
Dependent Claim
22 words
The method of remedying periodontal diseases as claimed in claim 4, wherein the water-soluble vinyl polymer is polyvinyl alcohol or polyvinyl pyrrolidone.
Claim 9
Dependent Claim
34 words
The method of remedying periodontal diseases as claimed in claim 1, wherein the water-soluble polymeric substance is a mixute of methyl cellulose, hydroxypropyl cellulose or hydroxypropyl cellulose with polyacrylic acid or a salt thereof.
Claim 10
Dependent Claim
33 words
The method of remedying periodontal diseases as claimed in claim 1, wherein the medicinal agent for remedy of periodontal diseases has germicidal action, an antibacterial action, a plaque-dissolving action or an anti-inflammatory action.
References Cited (Backward Citations)
CA822075A
Cited
US3972995A
Cited
WO1980000916A1
Cited
US4292299A
Cited
JPS56100714A
Cited
WO1982001129A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-02-10 | 1989-08-12 | 1990-02-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-02-10 | 1993-08-12 | 1994-02-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-02-10 | 1997-08-12 | 1998-02-11 | $7700.00 | Window Closed / Lapsed |