US4966767A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Ruminant dispensing device comprising agent displacement member
Assignee: Alza Corp
•
Filing: 1989-03-23
•
Granted: 1990-10-30
•
Expires: 2009-03-23
Abstract
Abstract A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) an expandable composition comprising a dense member in the space, (3) a composition comrising a beneficial agent and a non-toxic heat responsive carrier in the space, and (4) a passageway in the housing for delivering the beneficial agent from the dispensing device.
Inventors
- 👤 James B. Eckenhoff
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 11:00
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
177 words
A delivery system comprising: (a) a wall surrounding and defining an internal compartment, the wall comprising a composition permeable to the passage of fluid that enters the delivery system; (b) a beneficial agent in the compartment, said beneficial agent being a member selected from the group consisting of antibloat, anthelmintics, antibiotic, anti-infectious, antiparasitic, antimicrobial, and antiflea beneficial agents; (c) exit means in the wall for connecting the internal compartment with the exterior of the delivery system for delivering the beneficial agent from the delivery system; (d) means in the compartment for urging the beneficial agent through the exit means for delivering the beneficial agent over time; and, (e) a density member having a specific gravity of 2.2 to 7.6 and selected from the group consisting of iron, steel, iron-magnesium alloy, a mixture of cobalt and iron, copper oxide, iron oxide, and a mixture of copper oxide and iron comprising a specific gravity greater than the specific gravity of fluid that enters the delivery system blended in the means that urges the beneficial agent from the delivery system.
Claim 2
Dependent Claim
177 words
A delivery system comprising: (a) a wall surrounding and defining an internal compartment, the wall comprising a composition permeable to the passage of fluid that enters the delivery system; (b) a beneficial agent in the compartment, said beneficial agent being a member selected from the group consisting of antibloat, anthelmintics, antibiotic, anti-infectious, antiparasitic, antimicrobial, and antiflea beneficial agents; (c) exit means in the wall for connecting the internal compartment with the exterior of the delivery system for delivering the beneficial agent from the delivery system; (d) means in the compartment for urging the beneficial agent through the exit means for delivering the beneficial agent over time; and, (e) a density member having a specific gravity of 2.2 to 7.6 and selected from the group consisting of iron, steel, iron-magnesium alloy, a mixture of cobalt and iron, copper oxide, iron oxide, and a mixture of copper oxide and iron comprising a specific gravity greater than the specific gravity of fluid that enters the delivery system blended in the means that urges the beneficial agent from the delivery system.
Claim 3
Dependent Claim
43 words
A delivery system according to claim 1, wherein the beneficial agent is mixed with a member selected from the group consisting of a glyceride having a melting point of at least 31° C., and a block copolymer of 1,2-butylene oxide and ethylene oxide.
Claim 4
Dependent Claim
36 words
A delivery system according to claim 1, wherein the means for urging the beneficial agent from the delivery system is a member selected from the group consisting of poly(ethylene oxide), poly(acrylamide), poly(acrylic acid), and poly(hydroxyalkyl acrylate).
Claim 5
Dependent Claim
22 words
A delivery system according to claim 1, wherein the means for urging the beneficial agent from the delivery system is a hydrogel.
Claim 6
Dependent Claim
41 words
A delivery system according to claim 1, wherein the means for urging the beneficial agent through the exit in the wall is a composition comprising a hydrogel and an osmotically effective solute that exhibits an osmotic pressure gradient across the wall.
Claim 7
Dependent Claim
57 words
A delivery system according to claim 1, wherein the means for urging the beneficial agent through the exit means in the wall comprises a hydrogel and a member selected from the group consisting of iron, steel, iron magnesium alloy, a mixture of cobalt and iron, copper oxide, iron oxide, and a mixture of copper oxide and iron.
Claim 8
Dependent Claim
77 words
A delivery system for delivering a beneficial agent according to claim 1, wherein the means for urging the beneficial agent through the exit means in the wall comprises a hydrogel, an osmotically effective compound that exhibits an osmotic pressure gradient across the wall, and a density producing member selected from the group consisting of iron, steel, iron magnesium alloy, a mixture of cobalt and iron, copper oxide, iron oxide, and a mixture of copper oxide and iron.
Claim 9
Dependent Claim
29 words
A delivery system according to claim 1, wherein the beneficial agent is replaced by a member selected from the group consisting of a nutrient, feed additive, vitamin, and drug.
Claim 10
Dependent Claim
35 words
A delivery system according to claim 1, wherein the beneficial agent is a member selected from the group consisting of albendazole, avermectin, cambendazole, fenbendazole, ivermectin, levamisole, morantel, mebendazole, oxybendazole, oxfendazole, parbendazole, parziquantel, thiabendazole, and techloroform.
References Cited (Backward Citations)
US2340037A
Cited
FR1540258A
Cited
US3594469A
Cited
US3844285A
Cited
US3732865A
Cited
US3760804A
Cited
US3995631A
Cited
US4034756A
Cited
US3769805A
Cited
US3845770A
Cited
US3929132A
Cited
US3995632A
Cited
US4178361A
Cited
US4088864A
Cited
US4058122A
Cited
US4111202A
Cited
US4228149A
Cited
DE2729068A1
Cited
US4196187A
Cited
US4200098A
Cited
US4285987A
Cited
US4235236A
Cited
US4298003A
Cited
US4326522A
Cited
US4300558A
Cited
US4327725A
Cited
US4381780A
Cited
US4468220A
Cited
GB2122086A
Cited
US4595583A
Cited
US4612186A
Cited
US4692336A
Cited
US4627971A
Cited
US4717568A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-10-29 | 1994-04-30 | 1994-10-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-10-29 | 1998-04-30 | 1998-10-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-10-29 | 2002-04-30 | 2002-10-30 | $7700.00 | Window Closed / Lapsed |