US4627971A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Osmotic device with self-sealing passageway
Assignee: Alza Corp
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Filing: 1985-04-22
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Granted: 1986-12-09
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Expires: 2005-04-22
Abstract
Abstract An osmotic dispensing device is disclosed for delivering a medicine to a biological environment of use. The device comprises a semipermeable wall surrounding a compartment comprising a first layer comprising a beneficial agent formulation and a first passageway in the wall for delivering the beneficial agent formulation from the device, and a second layer of a composition comprising a hydrogel and a means for closing a second passageway formed during the manufacture of the device.
Inventors
- 👤 Atul D. Ayer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 23:48
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
142 words
An osmotic dispensing device for delivering a beneficial medicine formulation to an environment of use, comprising: (a) a wall comprising at least in part a semipermeable composition permeable to the passage of an exterior fluid present in the environment of use and substantially impermeable to the passage of the beneficial medicine formulation, which wall surrounds and forms: (b) a compartment; (c) a first passageway in the wall; (d) a second passageway in the wall; (e) a first layer comprising a beneficial medicine formulation in the compartment communicating with the first passageway; (f) a second layer comprising an expandable osmopolymer in the compartment, said second layer in communication with the second passageway; and (g) means possessing the ability to flow, form a film and seal the second passageway in the second layer for closing the second passageway during manufacture of the osmotic device.
Claim 2
Dependent Claim
142 words
An osmotic dispensing device for delivering a beneficial medicine formulation to an environment of use, comprising: (a) a wall comprising at least in part a semipermeable composition permeable to the passage of an exterior fluid present in the environment of use and substantially impermeable to the passage of the beneficial medicine formulation, which wall surrounds and forms: (b) a compartment; (c) a first passageway in the wall; (d) a second passageway in the wall; (e) a first layer comprising a beneficial medicine formulation in the compartment communicating with the first passageway; (f) a second layer comprising an expandable osmopolymer in the compartment, said second layer in communication with the second passageway; and (g) means possessing the ability to flow, form a film and seal the second passageway in the second layer for closing the second passageway during manufacture of the osmotic device.
Claim 3
Dependent Claim
158 words
A process for manufacturing an osmotic dispensing device for delivering a medicine to a fluid environment of use, the process comprising: (a) compressing a beneficial medicine formulation into a layer; (b) compressing a composition comprising a hydrogel and a means for closing a passageway formed during the manufacture of the osmotic device in a layer in contact with the layer comprising the beneficial medicine formulation; (c) surrounding the compressed contacting layer with a semipermeable wall; (d) laser drilling a passageway in the wall connecting the exterior of the device with the layer of beneficial medicine formulation for releasing the medicine formulation through the passageway from the device; (e) laser drilling a passageway in the wall distant from the passageway connected to the medicine formulation; and, (f) closing the passageway in the wall distant from the passageway connected to the medicine formulation by applying laser energy to the means for closing the passageway, whereby the means closes said passageway.
Claim 4
Dependent Claim
158 words
A process for manufacturing an osmotic dispensing device for delivering a medicine to a fluid environment of use, the process comprising: (a) compressing a beneficial medicine formulation into a layer; (b) compressing a composition comprising a hydrogel and a means for closing a passageway formed during the manufacture of the osmotic device in a layer in contact with the layer comprising the beneficial medicine formulation; (c) surrounding the compressed contacting layer with a semipermeable wall; (d) laser drilling a passageway in the wall connecting the exterior of the device with the layer of beneficial medicine formulation for releasing the medicine formulation through the passageway from the device; (e) laser drilling a passageway in the wall distant from the passageway connected to the medicine formulation; and, (f) closing the passageway in the wall distant from the passageway connected to the medicine formulation by applying laser energy to the means for closing the passageway, whereby the means closes said passageway.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-12-08 | 1990-06-09 | 1990-12-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-12-08 | 1994-06-09 | 1994-12-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-12-08 | 1998-06-09 | 1998-12-09 | $7700.00 | Window Closed / Lapsed |