Releasing incompatible pharmaceuticals from capsules - by including a second capsule inside the first

Abstract

Abstract The capsules have, inside the standard hard gelatin capsule, >=1 additional hard gelatin capsule with same or different dissolution characteristics. Inside the inner capsule is the same or different pharmaceutical carrier in same or different formulation, or a mixt. of various formulations. The hard gelatin may be replaced by other suitable capsule material, e.g., the inner capsule is of soft gelatin. Used for administration of medicines with physicochemical and/or pharmacokinetic incompatibilities such as vitamins and enzymes. The incompatible components can be kept apart during storage without need for special formulations and additional additives. By controlling capsule solubility, the time and position of release of ingredients can be regulated.

Inventors

• 👤 Rainer Dr Med Liedtke

Bibliographic Details