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US4957686A Expired / Lapsed US ⏱️ 0.0 years remaining

Use of bacteriophages to inhibit dental caries

Assignee: Individual
•
Filing: 1990-02-06
•
Granted: 1990-09-18
•
Expires: 2010-02-06
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Abstract

Abstract Because S. Sanguis is the first colonizer of newly cleaned teeth and because other bacteria then attach to it, the formation of dental plaque is reduced on newly cleaned teeth by introducing into the mouth bacteriophages which are parasitic to S. Sanguis. Because S. Sanguis is the means of attachment of plaque forming bacterial colonies to tooth surfaces and forms 10-15% of the organisms in plaque, destruction of S. Sanguis by introduction of its parasitic bacteriophages will remove plaque from teeth surfaces. And removal of plaque containing acid forming bacteria and other harmful bacteria reduces the incidence of dental caries and other disease.

Inventors

  • 👤 Alan H. Norris

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 20:47
CPC Classifications
A; A61; A61K; A61K35/00; A61K35/66; A61K35/76; A61K8/00; A61K8/18; A61K8/96; A61K8/99; A61Q; A61Q11/00; C; C12; C12N; C12N2795/00; C12N2795/00011; C12N2795/00032

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 46 words
A method of improved dental hygiene comprising introducing into the mouth bacteriophages parasitic to bacteria which possess the property of readily adhering to the salivary pellicle, said bacteria so providing receptor sites for other bacteria and so allowing a build up of plaque on the teeth.
Claim 2
Independent Claim 46 words
A method of improved dental hygiene comprising introducing into the mouth bacteriophages parasitic to bacteria which possess the property of readily adhering to the salivary pellicle, said bacteria so providing receptor sites for other bacteria and so allowing a build up of plaque on the teeth.
Claim 3
Dependent Claim 10 words
Claim 1, in which the said bacteria are S. Sanguis.
Claim 4
Independent Claim 36 words
A method of improved dental hygiene comprising introducing into the mouth a mixture of bacteriophages parasitic to bacteria normally present in the mouth, said mixture of bacteriophages containing at least one bacteriophage parasitic to S. Sanguis.
Claim 5
Independent Claim 36 words
A method of improved dental hygiene comprising introducing into the mouth a mixture of bacteriophages parasitic to bacteria normally present in the mouth, said mixture of bacteriophages containing at least one bacteriophage parasitic to S. Sanguis.
Claim 6
Dependent Claim 9 words
Claim 1, wherein the bacteriophages are incorporated in toothpaste.
Claim 7
Dependent Claim 9 words
Claim 1, wherein the bacteriophages are incorporated in toothpowder.
Claim 8
Dependent Claim 10 words
Claim 1, wherein the bacteriophages are incorporated in dental floss.
Claim 9
Dependent Claim 10 words
Claim 1, wherein the bacteriophages are incorporated in chewing gum.
Claim 10
Dependent Claim 10 words
Claim 1, wherein the bacteriophages are incorporated in oral tablets.
Claim 11
Dependent Claim 10 words
Claim 1, wherein the bacteriophages are incorporated in mouthwash solutions.
Claim 12
Dependent Claim 11 words
Claim 1, wherein the bacteriophages are incorporated in sweets and candy.

References Cited (Backward Citations)

US2944941A Cited
SU727195A1 Cited
US4150116A Cited
US4337314A Cited
US4681762A Cited
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US4659561A Cited
US4631259A Cited
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US4891210A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-09-17 1994-03-19 1994-09-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1997-09-17 1998-03-19 1998-09-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2001-09-17 2002-03-19 2002-09-18 $7700.00 Window Closed / Lapsed

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