Patent US4946870A successfully refreshed from Google Patents.
US4946870A
Expired / Lapsed
US
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Delivery systems for pharmaceutical or therapeutic actives
Assignee: Union Carbide Chemicals and Plastics Technology LLC
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Filing: 1988-11-08
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Granted: 1990-08-07
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Expires: 2008-11-08
Abstract
Abstract Delivery systems containing at least one aminopolysaccharide derivative are provided for the delivery of pharmaceutical or therapeutic actives to a desired topical or mucous membrane site in a subject, and wherein upon delivery, the systems provides a biocompatible, substantive, gas permeable, film from which actives are available at the designated site.
Inventors
- 👤 Emmett M. Partain, III.
- 👤 II. George L. Brode
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 23:10
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K8/00; A61K8/18; A61K8/72; A61K8/73; A61K8/736; A61K47/00; A61K47/30; A61K47/36; A61K9/0012; A61K9/0014; A61K9/7015; A61L; A61L26/00; A61L26/0009; A61L26/0023; A61L26/0061; A61L26/0076; A61Q; A61Q17/00; A61Q17/04; A61Q19/00; B; B01; B01D; B01D71/00; B01D71/06; B01D71/08; C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0024; C08B37/0027; C08B37/003; C08L; C08L5/00; C08L5/08; A61K2800/00; A61K2800/40; A61K2800/54; A61K2800/542; A61K2800/5426; A61Q7/00; Y; Y10; Y10S; Y10S261/00; Y10S261/88; Y10S424/00; Y10S424/15
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
92 words
A biocompatible, substantive, film-forming delivery system for the delivery of pharmaceutical or therapeutic actives to a desired topical site of a subject, said system being comprised of pharmaceutical of therapeutic actives and from about 0.1 to about 99.99 weight percent of the system of at least one aminopolysaccharide selected from the group consisting of: (1) chitosonium polymers, and (2) covalent chitosan derivatives, and wherein said system after delivery to said site, provides a non-irritating, substantive, gas permeable, film from which the actives are available for treatment of said subject at said site.
Claim 2
Dependent Claim
92 words
A biocompatible, substantive, film-forming delivery system for the delivery of pharmaceutical or therapeutic actives to a desired topical site of a subject, said system being comprised of pharmaceutical of therapeutic actives and from about 0.1 to about 99.99 weight percent of the system of at least one aminopolysaccharide selected from the group consisting of: (1) chitosonium polymers, and (2) covalent chitosan derivatives, and wherein said system after delivery to said site, provides a non-irritating, substantive, gas permeable, film from which the actives are available for treatment of said subject at said site.
Claim 3
Dependent Claim
13 words
The delivery system of claim 1 wherein said aminopolysaccharide is a chitosonium polymer.
Claim 4
Dependent Claim
14 words
The delivery system of claim 1 wherein said aminopolysaccharide is a covalent chitosan derivative.
Claim 5
Dependent Claim
24 words
The delivery system of claim 1 wherein said aminopolysaccharide is chitosonium pyrrolidone carboxylate; chitosonium niacinate, chitosonium itaconate, chitosonium salicylate, chitosonium lactate or chitosonium glycolate.
Claim 6
Dependent Claim
14 words
The delivery system of claim 1 wherein said aminopolysaccharide is blended with hyaluronic acid.
Claim 7
Dependent Claim
12 words
The delivery system of claim 1 which contains a pharmaceutically acceptable diluent.
Claim 8
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of a film.
Claim 9
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of a gel.
Claim 10
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of a patch.
Claim 11
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of an aerosol.
Claim 12
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of a suppository.
Claim 13
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of a fibre.
Claim 14
Dependent Claim
14 words
The delivery system of claim 1 which is in the form of a rod.
Claim 15
Dependent Claim
13 words
The delivery system of claim 1 which is in the form of microspheres.
Claim 16
Dependent Claim
17 words
The delivery system of claim 1 which is in the form of a hemostatic device or solution.
Claim 17
Dependent Claim
21 words
The delivery system of claim 1 which is a device selected from the group consisting of a pad, sponge and suture.
Claim 18
Dependent Claim
14 words
The delivery system of claim 16 which is in the form of a suture.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-08-06 | 1994-02-05 | 1994-08-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-08-06 | 1998-02-05 | 1998-08-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-08-06 | 2002-02-05 | 2002-08-07 | $7700.00 | Window Closed / Lapsed |