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US4942241A
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1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
Assignee: Sanofi Aventis France
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Filing: 1989-08-21
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Granted: 1990-07-17
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Expires: 2009-08-21
Abstract
Abstract Compounds of the formulas <IMAGE> +TR <IMAGE> wherein: Y is an alkylene bridge of 1-9 carbon atoms; R' is lower-alkyl or hydroxy-lower-alkyl of 1-5 carbon atoms; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and R8 is hydrogen or lower-alkyl of 1-5 carbon atoms, are useful as antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
Inventors
- 👤 Guy D. Diana
- 👤 Thomas R. Bailey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 00:45
CPC Classifications
C; C07; C07D; C07D271/00; C07D271/02; C07D271/06; C07D413/00; C07D413/02; C07D413/12
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
41 words
A compound of the formula ##STR25## wherein: Y is an alkylene bridge of 3-9 carbon atoms; R 1 and R 2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and R 8 is hydrogen or lower-alkyl of 1-5 carbon atoms.
Claim 2
Dependent Claim
41 words
A compound of the formula ##STR25## wherein: Y is an alkylene bridge of 3-9 carbon atoms; R 1 and R 2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and R 8 is hydrogen or lower-alkyl of 1-5 carbon atoms.
Claim 3
Dependent Claim
5 words
5-[3,5-Dimethyl-4-(3-ethynylpropoxy)phenyl]-3-methyl-1,2,4-oxadiazole, according to claim 1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-07-16 | 1994-01-15 | 1994-07-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-07-16 | 1998-01-15 | 1998-07-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-07-16 | 2002-01-15 | 2002-07-17 | $7700.00 | Window Closed / Lapsed |