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US4939171A Expired / Lapsed US ⏱️ 0.0 years remaining

Sebosuppressive topical preparations

Assignee: Henkel AG and Co KGaA
•
Filing: 1988-11-10
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Granted: 1990-07-03
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Expires: 2008-11-10
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Abstract

Abstract Alkyl and alkenyl aryl ether derivatives corresponding to the formula: ##STR1## in which R 1 is a saturated cycloaliphatic C 6 -C 20 alkyl group or a mono- or polyunsaturated, linear, branched or cycloaliphatic C 6 -C 20 alkyl group and R 2 is a C 1 -C 4 hydroxyalkyl group, a C 3 or C 4 hydroxyalkenyl group, a group --COOR 3 , --CH 2 --COOR 3 , --CH 2 --CH 2 --COOR 3 or --CH═CH--COOR 3 , are suitable as sebosuppressive agents in cosmetic or pharmaceutical preparations for topical application to the hair and to the skin.

Inventors

  • 👤 Hinrich Moeller
  • 👤 Norbert Banduhn

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-06 14:58
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/21; A61K31/215; A61K31/235; A61K31/075; A61K31/085; A61K31/185; A61K31/19; A61K31/22; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/34; A61K8/36; A61K8/368; A61K8/37; A61P; A61P3/00; A61P3/06; A61Q; A61Q19/00; A61Q19/008; A61Q5/00; A61Q5/008; A61Q5/02

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 163 words
A preparation suitable for topical application to human skin, comprising a sebosuppressive effective amount of a compound corresponding to the formula: ##STR3## in which (a) R 1 is a monovalent saturated hydrocarbon group containing at least one cyclopentane, cyclohexane, or cycloheptane ring nucleus and a total of about 6-20 carbon atoms; or a mono- or polyunsaturated, linear, branched, or cycloaliphatic group having about 6-20 carbon atoms; (b) R 2 is selected from the group consisting of about C 1 -C 4 hydroxy-alkyl, about C 3 or C 4 hydroxyalkenyl, --COOR 3 , --CH 2 --COOR 3 , --CH 2 --CH 2 --COOR 3 , and --CH═CH--COOR 3 , wherein R 3 is an about C 1 -C 4 alkyl group, an about C 2 -C 4 hydroxyalkyl group, an alkoxyalkyl group with about 1 to 4 carbon atoms in the alkoxy group and about 2 to 4 carbon atoms in the alkyl group, hydrogen, or a salt-forming cation and a topical vehicle therefore.
Claim 2
Dependent Claim 163 words
A preparation suitable for topical application to human skin, comprising a sebosuppressive effective amount of a compound corresponding to the formula: ##STR3## in which (a) R 1 is a monovalent saturated hydrocarbon group containing at least one cyclopentane, cyclohexane, or cycloheptane ring nucleus and a total of about 6-20 carbon atoms; or a mono- or polyunsaturated, linear, branched, or cycloaliphatic group having about 6-20 carbon atoms; (b) R 2 is selected from the group consisting of about C 1 -C 4 hydroxy-alkyl, about C 3 or C 4 hydroxyalkenyl, --COOR 3 , --CH 2 --COOR 3 , --CH 2 --CH 2 --COOR 3 , and --CH═CH--COOR 3 , wherein R 3 is an about C 1 -C 4 alkyl group, an about C 2 -C 4 hydroxyalkyl group, an alkoxyalkyl group with about 1 to 4 carbon atoms in the alkoxy group and about 2 to 4 carbon atoms in the alkyl group, hydrogen, or a salt-forming cation and a topical vehicle therefore.
Claim 3
Dependent Claim 55 words
A preparation according to claim 1, wherein R 1 contains a cyclohexyl nucleus, and R 2 is a group, --CH 2 OH, --CH═CH--CH 2 OH, --COOR 3 , --CH 2 --CH 2 --COOR 3 or --CH═CH--COOR 3 , where R 3 is hydrogen, a salt-forming cation, or an about C 1 -C 4 alkyl group.
Claim 4
Dependent Claim 24 words
A preparation according to claim 1, wherein R 1 is a group derived from unsaturated terpene alcohols by removal of one hydroxyl group therefrom.
Claim 5
Dependent Claim 21 words
A preparation according to claim 3, wherein R 1 is a geranyl, neryl, nerolidyl, farnesyl, 6,10-dimethyl-5,9-undecadienyl, β-citronellyl, phytyl or isophytyl group.
Claim 6
Dependent Claim 26 words
A preparation according to claim 4, wherein the amount of sebosuppressive compound is about 0.0005 to about 0.5 weight percent of the preparation as a whole.
Claim 7
Dependent Claim 26 words
A preparation according to claim 3, wherein the amount of sebosuppressive compound is about 0.0005 to about 0.5 weight percent of the preparation as a whole.
Claim 8
Dependent Claim 26 words
A preparation according to claim 2, wherein the amount of sebosuppressive compound is about 0.0005 to about 0.5 weight percent of the preparation as a whole.
Claim 9
Dependent Claim 26 words
A preparation according to claim 1, wherein the amount of sebosuppressive compound is about 0.0005 to about 0.5 weight percent of the preparation as a whole.
Claim 10
Dependent Claim 21 words
A method for treating human skin or hair, comprising applying thereto a subsuppressive amount of a preparation according to claim 8.
Claim 11
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 7.
Claim 12
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 6.
Claim 13
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 5.
Claim 14
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 4.
Claim 15
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 3.
Claim 16
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 2.
Claim 17
Dependent Claim 17 words
A method for treating human skin or hair, comprising applying thereto a preparation according to claim 1.

References Cited (Backward Citations)

US4503244A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1993-07-02 1994-01-01 1994-07-03 $2000.00 Window Closed / Lapsed
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