US4503244A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Sebosuppressive topical cosmetic preparations containing alkoxybenzoic acid esters, process for inhibiting sebum production and alkoxybenzoic acid esters
Assignee: Henkel AG and Co KGaA
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Filing: 1983-12-12
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Granted: 1985-03-05
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Expires: 2003-12-12
Abstract
Abstract A topical cosmetic preparation for the treatment of seborrhea containing a sebosuppressively effective amount of at least one alkoxybenzoic acid ester having the formula <IMAGE> wherein R1 represents a C6-20-n-alkyl and R2 is a member selected from the group consisting of -CH2OR3, -C2H4OR3, -CH2OC2H4OR3, -CH2OH, -C2H4OH, -CH(CH3)OH, -CH2NR3R4, -C2H4NR3R4, -CO2R3 and -CH2CO2R3, wherein R3 and R4 are C1-4-alkyl, as an antiseborrheic, and further containing conventional vehicles and additives for topical application; as well as the process for reducing sebaceous cell sebum production in a mammal in need thereof using the above cosmetic preparation; and the alkoxybenzoic acid esters of the above formula.
Inventors
- 👤 Hinrich M/o/ ller
- 👤 Siegfried Wallat
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 13:19
CPC Classifications
A; A61; A61Q; A61Q19/00; A61Q19/008; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/33; A61K8/37; A61K8/375; A61Q5/00; A61Q5/008; A61Q5/02
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
128 words
A topical cosmetic preparation for the treatment of seborrhea containing a sebosuppressively effective amount of at least one alkoxybenzoic acid ester having the formula ##STR9## wherein R 1 represents a C 6-20 -n-alkyl and R 2 is a member selected from the group consisting of --CH 2 OR 3 , --C 2 H 4 OR 3 , --CH 2 OC 2 H 4 OR 3 , --CH 2 OH, --C 2 H 4 OH, --CH(CH 3 )OH, --CH 2 NR 3 R 4 , --C 2 H 4 NR 3 R 4 , --CO 2 R 3 and --CH 2 CO 2 R 3 , wherein R 3 and R 4 are C 1-4 -alkyl, as an antiseborrheic, and further containing conventional vehicles and additives for topical application.
Claim 2
Dependent Claim
128 words
A topical cosmetic preparation for the treatment of seborrhea containing a sebosuppressively effective amount of at least one alkoxybenzoic acid ester having the formula ##STR9## wherein R 1 represents a C 6-20 -n-alkyl and R 2 is a member selected from the group consisting of --CH 2 OR 3 , --C 2 H 4 OR 3 , --CH 2 OC 2 H 4 OR 3 , --CH 2 OH, --C 2 H 4 OH, --CH(CH 3 )OH, --CH 2 NR 3 R 4 , --C 2 H 4 NR 3 R 4 , --CO 2 R 3 and --CH 2 CO 2 R 3 , wherein R 3 and R 4 are C 1-4 -alkyl, as an antiseborrheic, and further containing conventional vehicles and additives for topical application.
Claim 3
Dependent Claim
27 words
The topical cosmetic preparation of claim 1 wherein said at least one alkoxybenzoic acid ester is present in an amount of from 0.01% to 10.0% by weight.
Claim 4
Dependent Claim
27 words
The topical cosmetic preparation of claim 1 wherein said at least one alkoxybenzoic acid ester is present in an amount of from 0.05% to 5.0% by weight.
Claim 5
Dependent Claim
135 words
A process for reducing sebaceous cell sebum production in a mammal in need thereof which comprises contacting said sebaceous cell in the skin of said mammal with an effective amount to reduce sebum production of at least one alkoxybenzoic acid ester having the formula ##STR10## wherein R 1 represents a C 6-20 -n-alkyl and R 2 is a member selected from the group consisting of --CH 2 OR 3 , --C 2 H 4 OR 3 , --CH 2 OC 2 H 4 OR 3 , --CH 2 OH, --C 2 H 4 OH, --CH(CH 3 )OH, --CH 2 NR 3 R 4 , --C 2 H 4 NR 3 R 4 , --CO 2 R 3 and --CH 2 CO 2 R 3 , wherein R 3 and R 4 are C 1-4 -alkyl.
Claim 6
Dependent Claim
135 words
A process for reducing sebaceous cell sebum production in a mammal in need thereof which comprises contacting said sebaceous cell in the skin of said mammal with an effective amount to reduce sebum production of at least one alkoxybenzoic acid ester having the formula ##STR10## wherein R 1 represents a C 6-20 -n-alkyl and R 2 is a member selected from the group consisting of --CH 2 OR 3 , --C 2 H 4 OR 3 , --CH 2 OC 2 H 4 OR 3 , --CH 2 OH, --C 2 H 4 OH, --CH(CH 3 )OH, --CH 2 NR 3 R 4 , --C 2 H 4 NR 3 R 4 , --CO 2 R 3 and --CH 2 CO 2 R 3 , wherein R 3 and R 4 are C 1-4 -alkyl.
Claim 7
Dependent Claim
98 words
An alkoxybenzoic acid ester having the formula ##STR11## wherein R 1 represents a C 6-20 -n-alkyl and R 2 is a member selected from the group consisting of --CH 2 OR 3 , --C 2 H 4 OR 3 , --CH 2 OC 2 H 4 OR 3 , --CH 2 OH, --C 2 H 4 OH, --CH(CH 3 )OH, --CH 2 NR 3 R 4 , --C 2 H 4 NR 3 R 4 , --CO 2 R 3 and --CH 2 CO 2 R 3 , wherein R 3 and R 4 are C 1-4 -alkyl.
Claim 8
Dependent Claim
98 words
An alkoxybenzoic acid ester having the formula ##STR11## wherein R 1 represents a C 6-20 -n-alkyl and R 2 is a member selected from the group consisting of --CH 2 OR 3 , --C 2 H 4 OR 3 , --CH 2 OC 2 H 4 OR 3 , --CH 2 OH, --C 2 H 4 OH, --CH(CH 3 )OH, --CH 2 NR 3 R 4 , --C 2 H 4 NR 3 R 4 , --CO 2 R 3 and --CH 2 CO 2 R 3 , wherein R 3 and R 4 are C 1-4 -alkyl.
Claim 9
Dependent Claim
21 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-decyl and R 2 is --CH 2 OCH 3 .
Claim 10
Dependent Claim
23 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-decyl and R 2 is --CH 2 OC 2 H 5 .
Claim 11
Dependent Claim
25 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-decyl and R 2 is --CH 2 OC 2 H 4 OCH 3 .
Claim 12
Dependent Claim
19 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-decyl and R 2 is --CH 2 OH.
Claim 13
Dependent Claim
25 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-decyl and R 2 is --CH 2 N(C 2 H 5 ) 2 .
Claim 14
Dependent Claim
21 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-dodecyl and R 2 is --CH 2 OCH 3 .
Claim 15
Dependent Claim
21 words
The alkoxybenzoic acid ester of claim 5 wherein R 1 is n-decyl and R 2 is --CO 2 CH 3 .
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1988-03-04 | 1988-09-03 | 1989-03-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1992-03-04 | 1992-09-03 | 1993-03-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1996-03-04 | 1996-09-03 | 1997-03-05 | $7700.00 | Window Closed / Lapsed |