Imide derivatives and their pharmaceutical use

Claim 1

A compound of the formula: wherein A is a carbonyl group or a sulfonyl group; B is either one of the formulas: ##STR102## (in which R 1 and R 2 are each a hydrogen atom, or either one of them is a hydrogen atom and the other is a hydroxyl group, a C 1 -C 5 alkyl group or a C 2 -C 6 alkanoyloxy group, or R 1 and R 2 are combined together to represent an oxo group, E is a methylene group, an ethylene group or an oxygen atom and the full line accompanying a broken line ( ) indicates a single bond or a double bond), ##STR103## (in which F is a methylene group or an ethylene group and R 1 , R 2 and the full line accompanying a broken line ( ) are each as defined above), ##STR104## (in which R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are each a hydrogen atom or a C 1 -C 5 alkyl group and R 1 , R 2 and the full line accompanying a broken line ( ) are each as defined above), or ##STR105## (in which R 9 and R 10 are each a C 1 -C 5 alkyl group) when A represents a carbonyl group, or B is a 1,2-phenylene group when A represents a sulfonyl group; W is a C 1 -C 6 alkylene group, a C 2 -C 6 alkenylene group, a C 2 -C 6 alkynylene group or a C 2 -C 6 alkylene group substituted with hydroxyl; and G is a hydrogen atom, a C 1 -C 5 alkyl group, a C 1 -C 5 alkoxy group, a halogen atom or a hydroxyl group, or its pharmaceutically acceptable salt.