US4408053A
Expired / Lapsed
US
⏱️ 0.0 years remaining
(4-Piperidyl)-substituted phenyl ketones
Assignee: Aventis Pharmaceuticals Inc
•
Filing: 1982-08-06
•
Granted: 1983-10-04
•
Expires: 2002-08-06
Abstract
Abstract Novel 3-(4-piperidyl)-1,2-benzisoxazoles, intermediates and processes for the preparation thereof, and methods for alleviating pain utilizing compounds or compositions thereof are disclosed.
Inventors
- 👤 Joseph T. Strupczewski
- 👤 Beth A. Gardner
- 👤 Richard C. Allen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 16:26
CPC Classifications
C; C07; C07D; C07D413/00; C07D413/02; C07D413/04; C07D211/00; C07D211/04; C07D211/06; C07D211/08; C07D211/18; C07D211/26; C07D211/28; C07D211/30; C07D211/32; C07D211/36; C07D211/60; C07D211/62
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
70 words
A compound of the formula ##STR13## wherein R is hydrogen, loweralkyl, benzyl or a group of the formula ##STR14## wherein R 1 is hydrogen, loweralkyl or a group of the formula OR 2 wherein R 2 is benzyl; X is hydrogen, loweralkyl, loweralkoxy, halogen or hydroxy; Z is halogen or hydroxy; m is 1 or 2; the optical antipodes thereof; or salts thereof when R is hydrogen, loweralkyl or benzyl.
Claim 2
Dependent Claim
70 words
A compound of the formula ##STR13## wherein R is hydrogen, loweralkyl, benzyl or a group of the formula ##STR14## wherein R 1 is hydrogen, loweralkyl or a group of the formula OR 2 wherein R 2 is benzyl; X is hydrogen, loweralkyl, loweralkoxy, halogen or hydroxy; Z is halogen or hydroxy; m is 1 or 2; the optical antipodes thereof; or salts thereof when R is hydrogen, loweralkyl or benzyl.
Claim 3
Dependent Claim
8 words
The compound of claim 1 which is 1-methyl-4-(2-chloro-5-methylbenzoyl)piperidine.
Claim 4
Dependent Claim
8 words
The compound of claim 1 which is 4-(2,4-difluorobenzoyl)-N-formylpiperidine.
Claim 5
Dependent Claim
8 words
The compound of claim 1 which is 1-acetyl-4-(2-hydroxy-5-methoxybenzoyl)piperidine.
Claim 6
Dependent Claim
8 words
The compound of claim 1 which is 1-acetyl-4-(2,4-difluorobenzoyl)piperidine.
Claim 7
Dependent Claim
8 words
The compound of claim 1 which is 1-acetyl-4-(2-hydroxy-4,5-dimethoxybenzoyl)piperidine.
Claim 8
Dependent Claim
8 words
The compound of claim 1 which is 1-acetyl-4-(5-fluoro-2-hydroxybenzoyl)piperidine.
Claim 9
Dependent Claim
8 words
The compound of claim 1 which is 1-acetyl-4-(2,4-dichloro-benzoyl)piperidine.
Claim 10
Dependent Claim
8 words
The compound of claim 1 which is 4-(2,4-difluorobenzoyl)piperidine.
Claim 11
Dependent Claim
8 words
The compound of claim 1 which is 4-(2-hydroxy-4-methoxybenzoyl)piperidine.
Claim 12
Dependent Claim
8 words
The compound of claim 1 which is 4-(2-hydroxy-5-methoxoybenzoyl)piperidine.
Claim 13
Dependent Claim
8 words
The compound of claim 1 which is 4-(2,4-dichlorobenzoyl)piperidine.
Claim 14
Dependent Claim
12 words
The compound of claim 1 which is 4-(2-hydroxy-4-methoxybenzoyl)-1-piperidine carboxylic acid, phenylmethyl ester.
Claim 15
Dependent Claim
8 words
The compound of claim 1 which is 1-benzyl-4-(2-hydroxy-4-methoxybenzoyl)piperidine.
Claim 16
Dependent Claim
8 words
The compound of claim 1 which is 1-methyl-4-(2,6-difluorobenzoyl)piperidine.
Claim 17
Dependent Claim
8 words
The compound of claim 1 which is 4-(2-fluorobenzoyl)-1-methylpiperidine.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-10-03 | 1987-04-04 | 1987-10-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-10-03 | 1991-04-04 | 1991-10-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-10-03 | 1995-04-04 | 1995-10-04 | $7700.00 | Window Closed / Lapsed |