US4920098A
Expired / Lapsed
US
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Nutritional support or therapy for individuals at risk or under treatment for atherosclerotic vascular, cardiovascular, and/or thrombotic diseases
Assignee: Baxter International Inc
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Filing: 1989-08-28
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Granted: 1990-04-24
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Expires: 2009-08-28
Abstract
Abstract A method is provided for individuals under treatment for or at risk of atherosclerotic, vascular, cardiovascular, and/or thrombotic disease by administering a composition which comprises a protein source; a carbohydrate source; and at least one lipid selected from the group consisting of: gamma-linolenic acid; eicosapentaenoic acid; docosahexaenoic acid; sterodonic acid; and linolenic acid. Both an enteral and parenteral composition are provided.
Inventors
- 👤 Richard Cotter
- 👤 Robert C. Johnson
- 👤 Michael Ward
- 👤 David C. Madsen
- 👤 Anthony J. Valicenti
- 👤 Michael P. Menard
- 👤 Hugh N. Tucker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:19
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0029; A23; A23L; A23L33/00; A23L33/10; A23L33/115; A23L33/12; A23L33/17; A23L33/18
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
86 words
A method for providing cardiac therapy to an individual in need of same through a parenteral regimen comprising: a. a therapeutically effective amount of a protein source which includes a high biological value protein, amino acids including branched-chain amino acids and L-carnitine; b. a therapeutically effective amount of a polysaccharide source supplemented with ribose and/or xylitol; and c. a therapeutically effective amount of a lipid emulsion consistently essentially of a natural oil containing unsaturated fatty acids of 11 to 26 carbons in length, and an emulsifier.
Claim 2
Independent Claim
86 words
A method for providing cardiac therapy to an individual in need of same through a parenteral regimen comprising: a. a therapeutically effective amount of a protein source which includes a high biological value protein, amino acids including branched-chain amino acids and L-carnitine; b. a therapeutically effective amount of a polysaccharide source supplemented with ribose and/or xylitol; and c. a therapeutically effective amount of a lipid emulsion consistently essentially of a natural oil containing unsaturated fatty acids of 11 to 26 carbons in length, and an emulsifier.
Claim 3
Dependent Claim
17 words
The method of claim 1, wherein said natural oil comprises 5 to 20% of the lipid emulsion.
Claim 4
Dependent Claim
31 words
The method of claim 1, wherein the amino acids include: L-Arginine; L-Leucine; L-Isoleucine; L-Lysine; L-Valine; L-Phenylalanine; L-Histidine; L-Threonine; L-methionine; L-Tryptophan; L-Alanine; L-Proline; L-Serine; L-Tyrosine; amino acetic acid; isoleucine; leucine; and valine.
Claim 5
Dependent Claim
21 words
The method of claim 1, wherein said medium chain fatty acids comprise 50 to about 75% of the total lipid content.
Claim 6
Independent Claim
86 words
A method of providing cardiac therapy to an individual in need of same utilizing an enteral regimen comprising: a. a therapeutically effective amount of a protein source which includes a high biological value protein, amino acids including branched-chain amino acids and L-carnitine; b. a therapeutically effective amount of a polysaccharide source supplemented with ribose and/or xylitol; and c. a therapeutically effective amount of a lipid emulsion consistently essentially of a natural oil containing unsaturated fatty acids of 11 to 26 carbons in length, and an emulsifier.
Claim 7
Independent Claim
86 words
A method of providing cardiac therapy to an individual in need of same utilizing an enteral regimen comprising: a. a therapeutically effective amount of a protein source which includes a high biological value protein, amino acids including branched-chain amino acids and L-carnitine; b. a therapeutically effective amount of a polysaccharide source supplemented with ribose and/or xylitol; and c. a therapeutically effective amount of a lipid emulsion consistently essentially of a natural oil containing unsaturated fatty acids of 11 to 26 carbons in length, and an emulsifier.
Claim 8
Dependent Claim
17 words
The method of claim 5, wherein said natural oil comprises 5 to 20% of the lipid emulsion.
Claim 9
Dependent Claim
31 words
The method of claim 5 wherein the amino acids include: L-arginine; L-leucine; L-isoleucine; L-lysine; valine; L-phenylalanine; L-histidine; L-threonine; L-methionine; L-tryptophan; L-alanine; L-proline; L-serine; L-tyrosine; amino acetic acid; isoleucine; leucine; and valine.
Claim 10
Dependent Claim
21 words
The method of claim 5, wherein said medium chain fatty acids comprise 50 to about 75% of the total lipid content.
Claim 11
Independent Claim
94 words
A method for providing therapy to an individual at risk or under treatment for vascular, cardiovascular, or thrombotic diseases comprising the steps of: a. administering a therapeutically effective amount of a protein source which includes a high biological value protein, amino acids including branched-chain amino acids and L-carnitine; b. administering a therapeutically effective amount of a polysaccharide source supplemented with ribose and/or xylitol; and c. administering a therapeutically effective amount of a lipid emulsion consistently essentially of a natural oil containing unsaturated fatty acids of 11 to 26 carbons in length, and an emulsifier.
Claim 12
Independent Claim
94 words
A method for providing therapy to an individual at risk or under treatment for vascular, cardiovascular, or thrombotic diseases comprising the steps of: a. administering a therapeutically effective amount of a protein source which includes a high biological value protein, amino acids including branched-chain amino acids and L-carnitine; b. administering a therapeutically effective amount of a polysaccharide source supplemented with ribose and/or xylitol; and c. administering a therapeutically effective amount of a lipid emulsion consistently essentially of a natural oil containing unsaturated fatty acids of 11 to 26 carbons in length, and an emulsifier.
Claim 13
Dependent Claim
17 words
The method of claim 9, wherein said natural oil comprises 5 to 20% of the lipid emulsion.
Claim 14
Dependent Claim
31 words
The method of claim 9, wherein the amino acids include: L-arginine; L-leucine; L-isoleucine; L-lysine; L-valine; L-phenylalanine; L-histidine; L-theronine; L-methionine; L-tryptophan; L-alanine; L-proline; L-serine; L-tyrosine; amino acetic acid; isoleucine; leucine; and valine.
Claim 15
Dependent Claim
21 words
The method of claim 5, wherein said medium chain fatty acids comprise 50 to about 75% of the total lipid content.
Claim 16
Dependent Claim
19 words
The method of claim 9 including the step of administering the protein source, polysaccharide source, and lipid emulsion parenterally.
Claim 17
Dependent Claim
19 words
The method of claim 9 including the step of administering the protein source, polysaccharide source, and lipid emulsion enterally.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1993-04-23 | 1993-10-23 | 1994-04-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1997-04-23 | 1997-10-23 | 1998-04-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2001-04-23 | 2001-10-23 | 2002-04-24 | $7700.00 | Window Closed / Lapsed |